Herbert Hultgren Papers, 1940-1998 (MSS 0628)

Extent: 4 Linear feet (11 archives boxes)

Papers of Herbert Hultgren, cardiologist, mountain climber, researcher in high altitude medicine, and specialist in the study of high altitude pulmonary edema (HAPE). Hultgren and his colleague, Dr. Warren Spickard, were the first to publish a full account of high-altitude pulmonary edema in an English language publication. The papers contain materials related to Hultgren's work in Peru in the early 1960s on HAPE; drafts and production materials for his self-published textbook entitled HIGH ALTITUDE MEDICINE; a complete collection of his reprints; and files related to his important journal articles. The bulk of the collection is concerned with Hultgren's research on high altitude pulmonary edema (HAPE) and preparation of the book HIGH ALTITUDE MEDICINE and contains notebooks, drafts, notes, correspondence, data from experiments and patient observations, and reference articles. Also included are files documenting Hultgren's work on cardiac catheterization and establishment of first catheterization laboratory in Stanford, as well as his observation of cases of severe starvation in concentration camp survivors conducted while he served in Europe with U.S. Medical Corps in the end of the World War II. The papers are arranged in six series: 1) NOTEBOOKS, 2) SUBJECT FILES, 3) JOURNAL ARTICLES, 4) HIGH ALTITUDE MEDICINE - BOOK MATERIALS, 5) MISCELLANEOUS MATERIALS, and 6) REPRINTS.

Herbert Nils Hultgren was born on August 29, 1917, in Santa Rosa, California. He attended Santa Rosa Junior College and then Stanford University where he graduated in 1939. Hultgren attended the Stanford School of Medicine and graduated in 1943. He served in the U.S. Army in Europe between 1944 and 1945 where he observed starved prisoners from German concentration camps. Before joining the Stanford faculty in 1948, he completed residencies in internal medicine and pathology at Stanford. He attained the rank of professor at Stanford School of Medicine and served as chief of the Cardiology Division at Stanford Medical School and later at the Veterans Administration Hospital, Palo Alto, California. Hultgren designed and established the first cardiac catheterization laboratory in Northern California.

In 1959, Hultgren and his colleague, Dr, Warren Spickard, traveled to Peru and visited the Chulec General Hospital where they encountered high altitude pulmonary edema, known locally as edema of the lungs in newcomers. They reviewed the reports on 41 cases and presented the data in the Stanford Medical Bulletin.

In 1990, Hultgren received the prestigious Albion W. Hewlett Award for excellence in patient care, teaching, and research by his fellow Stanford University faculty members. He served as chairman of the Sub-specialty Board on Cardiovascular Disease of the American Board of Internal Medicine, President of the Association of University Cardiologists, President of the Western Association of Physicians, and was a member of the American Society of Clinical Investigation.

After his retirement, he continued part-time teaching and lecturing until his death in October 1997.

The papers of Herbert Nils Hultgren (1917-1997), a prominient cardiologist and pioneering researcher in high altitude medicine, document his research in high altitude medicine and cardiac catheterization. The bulk of the collection is related to Hultgren's research on high altitude pulmonary edema (HAPE) and preparation of his book entitled HIGH ALTITUDE MEDICINE. These materials comprise notebooks, subject files, and drafts of chapters. Materials related to his trip to Peru in 1960-1961 include a notebook and transcriptions of two tapes dictated by Hultgren while he was there. Also represented in the collection are materials documenting Hultgren's observations of severe cases of starvation in Nazi concentration camp survivors.

The papers are arranged in six series: 1) NOTEBOOKS, 2) SUBJECT FILES, 3) JOURNAL ARTICLES, 4) HIGH ALTITUDE MEDICINE - BOOK MATERIALS, 5) MISCELLANEOUS MATERIALS, and 6) REPRINTS.

SERIES 1: NOTEBOOKS

The NOTEBOOKS series contains manuscript notes on military medicine and experiments done at the 131st Evacuation and 59th Field Hospitals with the U.S. Army Medical Corps, observations of cases of severe starvation in Nazi concentration camp survivors, laboratory notes on cardiac catheterization and congenital heart disease, and observations of HAPE from a 1961 trip to Peru. The notebooks are organized chronologically.

SERIES 2: SUBJECT FILES

The SUBJECT FILES series, arranged alphabetically, contains research materials related to the study of coronary artery perfusion, high altitude pulmonary edema, hypercholesterolemia, and malnutrition. Included are data sheets, charts, X-rays, correspondence, and figures.

SERIES 3: JOURNAL ARTICLES

The JOURNAL ARTICLES series contains manuscript drafts, correspondence and research materials for selected journal articles.

SERIES 4: HIGH ALTITUDE MEDICINE - BOOK MATERIALS

The HIGH ALTITUDE MEDICINE series contains files that were generated during Hultgren's work on his HIGH ALTITUDE MEDICINE book. The files include correspondence, notes, reference materials, figures, and drafts. The series is arranged in three subseries: A) Research Materials, B) Drafts, and C) Editorial Materials.

A) The Research Materials subseries is arranged by chapter and contains notes, correspondence, and reference articles.

B) The Drafts subseries is also arranged by chapter and contains typescripts for each chapter of the book. Also included are figures, correspondence and reference articles.

C) The Editorial Materials subseries contains correspondence regarding monograph indexing and editorial notes.

SERIES 5: MISCELLANEOUS MATERIALS

The MISCELLANEOUS MATERIALS series contains Hultgren's curriculum vitae and a list of his publications. Also included are files related to a discussion of Hultgren's contribution to the study of HAPE syndrome, and transcriptions of tapes dictated by Hultgren in Peru in 1960 with his commentary on HAPE.

SERIES 6: REPRINTS

The REPRINTS series contains a complete collection of Hultgren's reprints arranged in numerical order.

Container List

NOTEBOOKS

Box: 1 Folder: 1
Physical Diagnosis, 1940
Box: 1 Folder: 2
Military Medicine, 1945 - 1946
Box: 1 Folder: 3
Notes on Experiments in the 131st Evacuation and 59th Field Hospitals, 1945 - 1946

Contains notebook, Hultgren's identification card, newspaper clipping, and typescript confession of Franz Ziereis, a concentration camp official.

Box: 1 Folder: 4
Laboratory notes, 1952

Contains notes on cardiac catheterization, congenital heart disease, plans for the opening of cardiac catheterization laboratory, and meeting notes.

Box: 1 Folder: 5
Peru Data Book, 1961

Contains observations of patients and catheter study notes.

SUBJECT FILES

Box: 1 Folder: 6
Charts

Undated.

Box: 1 Folder: 7
Coronary Artery Perfusion, 1969

Contains data sheets.

Box: 1 Folder: 8
Coronary Perfusion (Dog), 1970

Contains notes and X-rays of heart.

Box: 1 Folder: 9
Data sheets and charts

Undated. Contains tables numbered 1 through 54.

Box: 1 Folder: 10
Dugong Heart

Contains correspondence, notes, reference articles, and black-and-white photographs of heart.

Box: 1 Folder: 11
High Altitude Pulmonary Edema - Autopsy Studies and Data

Contains correspondence, notes, and reference materials.

Box: 1 Folder: 12
High Altitude Pulmonary Edema - Fatal cases

Contains letters, data sheets, and Rodman Wilson's report on Problems of Sickness and Rescue at High Altitude.

Box: 2 Folder: 1
High Altitude Pulmonary Edema - Pathology

Contains reprints of articles.

Box: 2 Folder: 2
Hypercholesterolemia - Kahn

Contains correspondence, data sheets, and medical records.

Box: 2 Folder: 3
Malnutrition, 1945

Contains correspondence, notes, and X-rays.

Box: 2 Folder: 4
Photographs

Charts, X-rays, and tables.

Box: 2 Folder: 5
X-rays of injected coronary arteries, 1969

Contains X-rays numbered 1 through 45 and two negatives with notes.

JOURNAL ARTICLES

Box: 2 Folder: 6
Cardiac Function Following Prosthetic Aortic Valve Replacement, 1969

With H. Hubis and N. Shumway. Contains draft, notes, correspondence, and figures.

Box: 2 Folder: 7
Cardiac Function Following Prosthetic Aortic Valve Replacement, 1969

With H. Hubis and N. Shumway. Contains reference materials.

Box: 2 Folder: 8
Cardiac Function Following Prosthetic Mitral Valve Replacement, 1968

With H. Hubis and N. Shumway. Contains correspondence and drafts.

Box: 3 Folder: 1
Cardiac Function Following Prosthetic Mitral Valve Replacement, 1968

With H. Hubis and N. Shumway. Contains manuscripts, charts, notes, and figures.

Box: 3 Folder: 2
Clinical and Laboratory Observations In Severe Starvation, 1951

Contains manuscripts, typescripts, galley proof, two letters, black-and-white photographs, and a reference article.

Box: 3 Folder: 3
History Of Cardiac Catheterization

Contains typescript, manuscript, and notes.

Box: 3 Folder: 4
History Of Cardiac Catheterization

Contains correspondence and black-and-white photographs. Correspondence dating back to 1958-1959.

Box: 3 Folder: 5
History Of Cardiac Catheterization

Contains reference materials.

Box: 4 Folder: 1
Syndrome Of Patent Ductus Arteriosus With Pulmonary Hypertension, 1953

With A. Selzer, A. Purdy, E. Holman, and F. Gerbode. Contains typescripts.

Box: 4 Folder: 2
Syndrome Of Patent Ductus Arteriosus With Pulmonary Hypertension, 1953

With A. Sezer, A. Purdy, E. Holman, and F. Gerbode. Contains notes, correspondence, and black-and-white photographs.

Box: 4 Folder: 3
Venous Pistol Shot Sounds, 1962

Contains typescripts, manuscripts, notes, and correspondence.

Box: 4 Folder: 4
Venous Pistol Shot Sounds, 1962

Contains charts, reference articles, and negatives.

HIGH ALTITUDE MEDICINE -- BOOK MATERIALS

Research Materials

Box: 4 Folder: 5
1. Physiologic Effects of High Altitude

Contains correspondence and reference materials.

Box: 4 Folder: 6
2. Respiration and Pulmonary Function

Contains correspondence and reference materials.

Box: 4 Folder: 7
3. Systematic Circulation

Contains a letter, notes, and reference articles.

Box: 4 Folder: 8
4. Pulmonary Circulation

Contains a letter, notes, and reference articles.

Box: 4 Folder: 9
5. Blood and Plasma Volume

Contains correspondence and reference articles.

Box: 5 Folder: 1
6. Central Nervous System

Contains letters, notes, and reference articles.

Box: 5 Folder: 2
7. Endocrine System

Contains notes and reference materials.

Box: 5 Folder: 3
8. Nutrition and Metabolism

Contains reference materials.

Box: 5 Folder: 4
9. Water, Electrolytes and Acid-Base Balance

Contains notes and reference articles.

Box: 5 Folder: 5
10. Acclimatization

Contains notes and reference articles.

Box: 5 Folder: 6
11. Exercise

Contains a letter and reference articles.

Box: 5 Folder: 7
12. Acute and Subacute Mountain Sickness

Contains notes, letters, and reference articles.

Box: 5 Folder: 8
13. High Altitude Pulmonary Edema

Contains correspondence, notes, and reference articles.

Box: 5 Folder: 9
14. High Altitude Cerebral Edema

Contains correspondence, notes, and reference articles.

Box: 6 Folder: 1
15. Chronic Mountain Sickness

Contains a letter, notes, tables, and reference articles.

Box: 6 Folder: 2
16. Sleep
Box: 6 Folder: 3
17. Systemic Edema

Contains letters and reference articles.

Box: 6 Folder: 4
19. Headache

Contains letter, notes, and articles.

Box: 6 Folder: 5
20. High Altitude Pulmonary Hypertension

Contains letters and reference materials.

Box: 6 Folder: 6
21. Retinal Hemorrhages

Contains letters, notes, and reference materials.

Box: 6 Folder: 7
22. Syncope

Contains letters, notes, typescripts, and reference materials.

Box: 6 Folder: 8
23. Coronary Artery Disease

Contains letters, notes, and reference articles.

Box: 6 Folder: 9
24. Congenital and Valvular Heart Disease

Contains a letter, notes, and reference materials.

Box: 6 Folder: 10
25. Systemic Hypertension

Contains correspondence, notes, and reference materials.

Box: 6 Folder: 11
26. Sickle Cell Disease

Contains a letter, notes, and reference materials.

Box: 6 Folder: 12
27. Pulmonary Disease

Contains notes and reference materials.

Box: 7 Folder: 1
28. Migraine

Contains a letter, reference materials, and notes.

Box: 7 Folder: 2
29. Sea Level Conditions

Contains letters, notes, and reference materials.

Box: 7 Folder: 3
30. Women and Altitude

Contains a letter, notes, and reference materials.

Box: 7 Folder: 4
High Altitude Man - Notes

Contains letters, notes, and reference materials.

Box: 7 Folder: 5
Appendix 1. Medicolegal Aspects

Contains correspondence, notes, and reference materials.

Box: 7 Folder: 6
Medico-Legal Problems (Clients not Passengers)

Contains notes and reference materials.

Box: 7 Folder: 7
Appendix 2. Selected High Altitude Monographs and Proceedings

Drafts

Box: 7 Folder: 8
Table of Contents

Contains drafts, notes, and correspondence.

Box: 7 Folder: 9
Introduction
Box: 7 Folder: 10
1. Physiologic Effects of High Altitude
Box: 7 Folder: 11
2. Respiration and Pulmonary Function
Box: 7 Folder: 12
3. Systemic Circulation
Box: 7 Folder: 13
4. Pulmonary Circulation
Box: 8 Folder: 1
5. Blood and Plasma Volume
Box: 8 Folder: 2
6. Central Nervous System
Box: 8 Folder: 3
7. Endocrine System
Box: 8 Folder: 4
8. Nutrition and Metabolism
Box: 8 Folder: 5
9. Water, Electrolytes and Acid-Base Balance
Box: 8 Folder: 6
10. Acclimatization
Box: 8 Folder: 7
11. Exercise
Box: 8 Folder: 8
12. High Altitude Man
Box: 8 Folder: 9
12. Acute and Subacute Mountain Sickness
Box: 8 Folder: 10
12. Acute and Subacute Mountain Sickness
Box: 8 Folder: 11
12. Acute and Subacute Mountain Sickness
Box: 9 Folder: 1
13. High Altitude Pulmonary Edema
Box: 9 Folder: 2
13. High Altitude Pulmonary Edema
Box: 9 Folder: 3
13. High Altitude Pulmonary Edema

Tables.

Box: 9 Folder: 4
14. High Altitude Celebral Edema
Box: 9 Folder: 5
15. Chronic Mountain Sickness
Box: 9 Folder: 6
16. Sleep
Box: 9 Folder: 7
17. Systemic Edema
Box: 9 Folder: 8
18. Thromboembolism
Box: 9 Folder: 9
19. Headache
Box: 9 Folder: 10
20. High Altitude Pulmonary Hypertension
Box: 9 Folder: 11
21. Retinal Hemorrhages
Box: 9 Folder: 12
22. Syncope
Box: 9 Folder: 13
23. Coronary Artery Disease and Altitude
Box: 9 Folder: 14
24. Congenital and Valvular Heart Disease
Box: 9 Folder: 15
25. Systemic Hypertension
Box: 9 Folder: 16
26. Sickle Cell Disease
Box: 9 Folder: 17
27. Pulmonary Disease
Box: 9 Folder: 18
28. Migraine
Box: 10 Folder: 1
29. Sea Level Conditions
Box: 10 Folder: 2
30. Women and Altitude
Box: 10 Folder: 3
Appendix 1. Medicolegal Aspects
Box: 10 Folder: 4
Appendix 2. Selected High Altitude Monographs and Proceedings
Box: 10 Folder: 5
Appendix 2. Medications Used For High Altitude Medical Problems

Contains correspondence, notes, drafts, and reference materials.

Editorial Materials

Box: 10 Folder: 6
Monograph Indexing

Contains correspondence and notes.

Box: 10 Folder: 7
Shirley Taylor Editorial Notes

MISCELLANEOUS MATERIALS

Box: 10 Folder: 8
Curriculum Vitae, 2004
Box: 10 Folder: 9
Hultgren's contributions to and work on high altitude pulmonary edema - discussion, 1960 - 1998

Contains Robert F. Grover, reprint of Hultgren's article "Lung Pathology In High Altitude Pulmonary Edema," transcriptions of tapes dictated by him in Peru in 1960, June 18 and July 23, a letter from Hultgren dated 1962, and a letter from Charles Houston to Hultgren from 1966.

Box: 10 Folder: 10
West, John, 1995 - 1998

Contains correspondence and enclosures. Correspondence concerned with early history of HAPE and Hultgren's contributions to the discussion of HAPE.

Box: 10 Folder: 11
Scientific American Medicine, 1993

Contains correspondence and tables.

REPRINTS

Box: 10 Folder: 12
Numbered Reprints 1-35
Box: 10 Folder: 13
Numbered Reprints 36-66
Box: 11 Folder: 1
Numbered Reprints 67-113
Box: 11 Folder: 2
Numbered Reprints 114-158
Box: 11 Folder: 3
Numbered Reprints 159-197