Leslie Orgel Papers, 1949-2007 (MSS 176)

Restrictions: Original media formats are restricted; researchers may request listening or viewing copies.

Extent: 32.8 Linear feet (79 archives boxes, 9 oversize folders, and 1 art bin item)

Papers of Leslie Eleazer Orgel (1927-2007), chemist and molecular biologist. Orgel was a senior fellow and research professor at the Salk Institute for Biological Studies, where he directed the Chemical Evolution Laboratory. The collection includes correspondence, writings, talks and lectures, research files, patents, administrative files, photographs, and audiovisual materials.

Leslie Eleazer Orgel was born in London, England, on January 12, 1927. He received his B.A. in chemistry with first class honors from the University of Oxford in 1949. In 1950 he was elected a fellow of Magdalen College and in 1951 was awarded his Ph.D. in chemistry at the University of Oxford.

Orgel started his career as a theoretical inorganic chemist and continued his studies in this field at Oxford, the California Institute of Technology and the University of Chicago. In 1955 he joined the chemistry department at the University of Cambridge, where he did work in transition metal chemistry, published articles and wrote a textbook, Transition Metal Chemistry: Ligand Field Theory (1960).

In 1964 Orgel was appointed senior fellow and research professor at the Salk Institute for Biological Studies, where he directed the Chemical Evolution Laboratory. He was also an adjunct professor in the Department of Chemistry and Biochemistry at the University of California, San Diego, and was one of five principal investigators in the NASA-sponsored NSCORT program in exobiology. Orgel also participated in NASA's Viking Mars Lander Program as a member of the Molecular Analysis Team that designed the gas chromatography mass spectrometer instrument.

Orgel wrote The Origins of Life: Molecules and Natural Selection (1970) and co-authored with Stanley Miller The Origins of Life on the Earth (1974). He published over three hundred articles in his research areas. In Britain he was awarded the Harrison Prize in 1956 for his work in inorganic chemistry and elected a fellow of the Royal Society in 1962. In the United States he received a Guggenheim Fellowship in 1971, the Evans Award from Ohio State University in 1975, and the H.C. Urey Medal from the International Society for the Study of the Origin of Life in 1993. He was an elected member of both the American Academy of Arts and Sciences and the National Academy of Sciences. Leslie Orgel died on October 27, 2007 in San Diego, California.

Papers of chemist and molecular biologist Leslie Eleazer Orgel (1927-2007). Orgel was a senior fellow and research professor at the Salk Institute for Biological Studies, where he directed the Chemical Evolution Laboratory. Orgel's research interests included nucleic acid chemistry, molecular evolution, prebiotic chemistry, and problems related to the origin of life. The collection includes correspondence, writings, talks and lectures, research files, patents, administrative files, photographs, and audiovisual materials.

Accession Processed in 2006

Arranged in seven series: 1) BIOGRAPHICAL MATERIAL, 2) CORRESPONDENCE, 3) WRITINGS, 4) CONTRACTS, GRANTS AND PROPOSALS, 5) CONFERENCES AND MEETINGS, 6) SUBJECT FILES, and 7) SALK INSTITUTE.

Accession Processed in 2018

Arranged in eight series: 8) BIOGRAPHICAL 9) CORRESPONDENCE, 10) TALKS AND LECTURES, 11) WRITINGS, 12) PROJECTS AND RESEARCH, 13) ORGANIZATIONS AND COMMITTEES, 14) PHOTOGRAPHS, and 15) SOUND AND VIDEO RECORDINGS.

Container List

Accession Processed in 2006

BIOGRAPHICAL MATERIAL

Scope and Content of Series

Series 1) BIOGRAPHICAL MATERIAL: Orgel's annotated wall calendars, newspaper clippings, and his application for naturalization as a U.S. citizen. Arranged alphabetically.

Oversize FB-208 Folder 2-3
Calendars, 1982 - 1996
Box 1 Folder 1
Newspaper clippings, 1967 - 1973
Box 1 Folder 2
United States Department of Justice. Immigration and Naturalization Service. Application for naturalization, 1989

CORRESPONDENCE

Scope and Content of Series

Series 2) CORRESPONDENCE: Orgel's incoming and outgoing professional and personal correspondence. Arranged in four subseries: A) Outgoing Chronological Files, B) General, C) Scientific, and D) Personal.

A) Outgoing Chronological Files: Copies of outgoing letters from 1964 to 1991.

B) General: Correspondence associated with routine laboratory business: letters of inquiry regarding possible employment, correspondence with suppliers, requests for visits, and cordial correspondence. In most cases, the incoming letters are accompanied by outgoing replies. Arranged chronologically.

C) Scientific: Correspondence with colleagues and other scientists regarding scientific and technical issues, arranged alphabetically by author. Prominent correspondents include Francis Crick, Robin Holliday, Jean-Michel Labouygues, Stanley Miller, Carl Sagan, S.A. Seleznev, and Eugene Wigner. Arranged alphabetically by surname or corporate name.

D) Personal: Letters to and from friends and correspondence related to personal interests, travel plans and projects. Arranged chronologically.

Outgoing Chronological Files

Box 1 Folder 3-6
Correspondence, 1964 - 1965
Box 2 Folder 1-12
Correspondence, 1966 - 1976
Box 3 Folder 1-11
Correspondence, 1977 - 1983
Box 4 Folder 1-10
Correspondence, 1983 - 1987
Box 5 Folder 1-8
Correspondence, 1987 - 1991
Box 6 Folder 1
Correspondence, 1991

General

Box 6 Folder 2-7
Correspondence, 1964 - 1989

Scientific

Box 7 Folder 1
A - Miscellaneous
Box 7 Folder 2
Altman, Sidney, 1984
Box 7 Folder 3
American Institute of Biological Sciences, 1973 - 1979
Box 7 Folder 4
American Journal of Human Genetics , 1978 - 1980

David E. Comings, editor.

Box 7 Folder 5
American Scientist , 1973 - 1979
Box 7 Folder 6
Arrhenius, Gustaf, 1974 - 1984
Box 7 Folder 7
Associated Scientific Publishers, 1973

F. Suater, Dept. managing director.

Box 7 Folder 8
Avracmides, George, 1982
Box 7 Folder 9-10
B - Miscellaneous
Box 7 Folder 11
Balasubramanian, R., 1983
Box 7 Folder 12
Baltscheffsky, Herrick, 1977 - 1978
Box 7 Folder 13
Ben-Nun, Akiva, 1971 - 1976
Box 7 Folder 14
Botkin, Daniel B., 1982 - 1983
Box 7 Folder 15
Brack, Andre, 1977 - 1982
Box 7 Folder 16
British Broadcasting Corporation, 1976 - 1980
Box 7 Folder 17
C - Miscellaneous
Box 7 Folder 18
Carmell, L., 1974
Box 7 Folder 19
Comfort, Alex, 1973 - 1978
Box 7 Folder 20
Crick, Francis H.C., 1965 - 1974
Box 7 Folder 21
D - Miscellaneous
Box 7 Folder 22
Danielli, James F., 1974 - 1980
Box 7 Folder 23
Dickerson, Richard E., 1979 - 1981
Box 7 Folder 24
Dyson, Freeman, 1981
Box 8 Folder 1
E - Miscellaneous
Box 8 Folder 2
Eirich, F.R., 1984
Box 8 Folder 3
Encyclopedia of Ignorance (Miranda Weston-Smith), 1974 - 1979
Box 8 Folder 4
Eschenmoser, A., 1966
Box 8 Folder 5
F - Miscellaneous
Box 8 Folder 6
Ferris, James P., 1969 - 1983
Box 8 Folder 7
G - Miscellaneous
Box 8 Folder 8
Galas, David J., 1973 - 1980
Box 8 Folder 9
Gallant, Jonathan A., 1977
Box 8 Folder 10
Gould, Stephen Jay, 1981
Box 8 Folder 11
Granada Television Limited (Jack Smith, executive producer), 1979 - 1980
Box 8 Folder 12
H - Miscellaneous
Box 8 Folder 13
Hendry, Lawrence B., 1981 - 1983
Box 8 Folder 14
Holliday, Robin, 1964 - 1978

See also Series 6: Aging.

Box 8 Folder 15
Horowitz, N.H., 1970 - 1984
Box 8 Folder 16
I - Miscellaneous
Box 8 Folder 17
Idiot papers and comments, 1964 - 1979
Box 8 Folder 18
International Society for the Study of the Origin of Life (ISSOL), 1989
Box 8 Folder 19
J - Miscellaneous
Box 8 Folder 20
K - Miscellaneous
Box 8 Folder 21
Kendrew, John C., 1967 - 1975
Box 8 Folder 22
Khorana, Gobind H., 1969 - 1978
Box 9 Folder 1
Kornberg, Arthur, 1968 - 1981
Box 9 Folder 2
L - Miscellaneous
Box 9 Folder 3
Labouygues, Jean-Michel, 1974 - 1982
Box 9 Folder 4
Lagerkvist, Ulf, 1977 - 1979
Box 9 Folder 5
Lasser, David, 1981 - 1982

Includes interview with Orgel.

Box 9 Folder 6
Leonard, Nelson, 1988 - 1989
Box 9 Folder 7
M - Miscellaneous
Box 9 Folder 8
Mandell, Arnold J., 1981 - 1982
Box 9 Folder 9
Michelson, A.M., 1967 - 1968
Box 9 Folder 10
Miles, Todd, 1971 - 1983
Box 9 Folder 11
Miller, Stanley L., 1975 - 1983
Box 9 Folder 12
Monod, Jacques, 1963 - 1973
Box 9 Folder 13
N - Miscellaneous
Box 9 Folder 14
National Academy of Sciences, 1990
Box 9 Folder 15
Nature (Elizabeth Hughes, publisher), 1981
Box 9 Folder 16
Neurologische Klinik der Universität, 1974 - 1975
Box 9 Folder 17
Ninio, Jacques, 1974 - 1981
Box 9 Folder 18
O - Miscellaneous
Box 9 Folder 19
Oro, John, 1965 - 1983
Box 9 Folder 20
P - Miscellaneous
Box 9 Folder 21
Paecht-Horowitz, Mella, 1972
Box 9 Folder 22
Peters, David, 1981
Box 9 Folder 23
Phillips, William, 1965 - 1966
Box 9 Folder 24
Pitha, Josef, 1969 - 1974
Box 9 Folder 25
Ponnamperuma, Cyril, 1965 - 1970
Box 9 Folder 26
R - Miscellaneous
Box 9 Folder 27
Rabinowitz, Joseph M., 1969 - 1970
Box 9 Folder 28
Reese, Colin B., 1981 - 1984
Box 10 Folder 1
Robins, Roland K., 1968 - 1969
Box 10 Folder 2
The Royal Society, 1970 - 1985
Box 10 Folder 3-4
S - Miscellaneous
Box 10 Folder 5
Sagan, Carl, 1973 - 1982
Box 10 Folder 6
Schwartz, Alan W., 1972 - 1981
Box 10 Folder 7
Seleznev, S.A., 1974 - 1975
Box 10 Folder 8
Sobell, Henry M., 1965 - 1982
Box 10 Folder 9
Stein, Gabriel, 1965 - 1968
Box 10 Folder 10
Strehler, Bernard L., 1974 - 1981
Box 10 Folder 11
T - Miscellaneous
Box 10 Folder 12
Thaxton, Charles B., 1981 - 1983
Box 10 Folder 13
Todd, John H., 1969
Box 10 Folder 14
Townes, Charles, 1970 - 1972
Box 10 Folder 15
Trends in Biochemical Sciences , 1975 - 1980

Joan Morgan, staff editor.

Box 10 Folder 16
Ts'o, Paul O.P., 1968 - 1976
Box 10 Folder 17
U - Miscellaneous
Box 10 Folder 18
Usher, David A., 1975 - 1983
Box 10 Folder 19
V - Miscellaneous
Box 10 Folder 20
Verheyden, Julien P.H., 1983
Box 10 Folder 21
W - Miscellaneous
Box 10 Folder 22
Watson, J.D., 1980
Box 10 Folder 23
Wells, Robert D., 1982 - 1984
Box 10 Folder 24
Westheimer, Frank H., 1970 - 1984
Box 11 Folder 1
Wigner, Eugene P., 1963 - 1970
Box 11 Folder 2
Worth Publishers, Inc., 1973
Box 11 Folder 3
Y - Miscellaneous
Box 11 Folder 4
Yates, F. Eugene, 1980
Box 11 Folder 4
Z - Miscellaneous
Box 11 Folder 6
Zubay, Geoffrey, 1979 - 1981
Box 11 Folder 7
Unidentified correspondents

Personal

Box 11 Folder 8-12
Correspondence, 1971 - 1992

WRITINGS

Scope and Content of Series

SERIES 3) WRITINGS. Organized in two subseries: A) Published, and B) Unpublished.

A) Published: Drafts, manuscripts, correspondence, redacted referee reports, reprints, and figures of Orgel's published research articles, beginning with his numbered chronological list of publications. The subseries contains 259 of the 302 listed titles, including the draft and correspondence for his textbook An Introduction to Transition Metal Chemistry: Ligand Field Theory (1960), the only representative from his work while in England. Also included are materials for his other two books, The Origins of Life: Molecules and Natural Selection (1973) and The Origins of Life on the Earth (1974), with Stanley L. Miller. Of particular interest are Orgel's files for two collaborative articles with Francis Crick, "Directed Panspermia" (#137) and "Selfish DNA: The Ultimate Parasite" (#186), which contain abundant correspondence. Arranged numerically by article number.

B) Unpublished: Drafts and correspondence for titles that do not appear on Orgel's publications list, arranged alphabetically by title.

Published

Box 11 Folder 13
List of publications, 1951 - 1997
Box 11 Folder 14
61 - An Introduction to Transition Metal Chemistry: Ligand Field Theory (1960), 1960
Box 11 Folder 15
87 - Induction of Mutations in Bacteriophage T4 with Divalent Manganese. With A. Orgel, 1965
Box 11 Folder 16
89 - Reactions of Bromomalononitrile with Bases. With James P. Ferris, 1965
Box 11 Folder 17
90 - Formation of Condensed Phosphate in Aqueous Solution. With A. Beck, 1965
Box 12 Folder 1
91 - Aminomalononitrile and 4-Amino-5- Cyanomidazole in Hydrogen Cyanide Polymerization and Adenine Synthesis. With James P. Ferris, 1965
Box 12 Folder 2
93 - Photochemical Synthesis of Condensed Phosphates. With A. Beck, 1965
Box 12 Folder 3
94 - An Unusual Photochemical Rearrangement in the Synthesis of Adenine from Hydrogen Cyanide. With James P. Ferris, 1966
Box 12 Folder 4
95 - Conditions for Purine Synthesis: Did Prebiotic Synthesis Occur at Low Temperatures? With R. Sanchez and J. Ferris, 1966

Includes photographs.

Box 12 Folder 5
96 - Studies in Prebiotic Synthesis. I. Aminomalononitrile and 4-Amino-5-Cyanomiclazole. With James P. Ferris, 1966
Box 12 Folder 6
97 - Cyanoacetylene in Prebiotic Synthesis. With R.A. Sanchez and J. Ferris, 1966
Box 12 Folder 7
101 - Nucleoside Synthesis Under Potentially Prebiotic Conditions. With C. Reid, 1967
Box 12 Folder 8
103 - Studies in Prebiotic Synthesis. II. Synthesis of Purine Precursors and Amino Acids from Aqueous Hydrogen Cyanide. With Robert A. Sanchez and James P. Ferris, 1967
Box 12 Folder 9
104 - The Non-Enzymatic Synthesis of Deoxyadenylate Oligonucleotides on a Polyuridylate Template. With H. Schneider-Bernloehr, et al, 1968
Box 12 Folder 10
105 - Studies in Prebiotic Synthesis. III. Synthesis of Pyrimidines from Cyanoacetylene and Cyanate. With James P. Ferris and Robert A. Sanchez, 1968
Box 12 Folder 11
106 - Specificity of Oligonucleotide Synthesis Directed by Polyuridylic Acid. With J. Sulston and R. Lohrmann, 1968
Box 12 Folder 12
107 - Prebiotic Synthesis: Phosphorylation in Aqueous Solution. With R. Lohrmann, 1968
Box 12 Folder 13
108 - Template-Directed Synthesis with Adenosine-5'-Phosphorimidazolide. With B.J. Weimann, et al, 1968
Box 12 Folder 14
109 - Non-Enzymic Synthesis of Deoxyadenulate Oligonucleotides on a Polyuridylate Template. With H. Schnieder-Bernloehr, et al, 1968
Box 12 Folder 15
110 - Studies in Prebiotic Synthesis. IV. The Conversion of 4-Aminoinidazole-5-Carbonitrile Derivatives to Purines. With Robert A. Sanchez and James P. Ferris, 1968
Box 12 Folder 16
111 - Partial Resolution of DL-Adenosine by Template Synthesis. With Schneider-Bernloehr, et al, 1968
Box 12 Folder 17
112 - Evolution of the Genetic Apparatus, 1968
Box 12 Folder 18
114 - Non-Enzymic Oligonucleotide Synthesis on a Polytidylate Template. With J. Sulston, et al, 1969
Box 12 Folder 19
115 - Phosphorylation of D-Ribose in Aqueous Solution. With M. Halmann and R.A. Sanchez, 1969
Box 12 Folder 20
116 - Specificity of Template-Directed Synthesis with Adenosine Nucleosides. With H. Schneider-Bernloehr, et al, 1970
Box 12 Folder 21
117 - Studies in Prebiotic Synthesis. V. Synthesis and Photoanomerization of Pyrimidine Nucleosides. With Robert A. Sanchez, 1970
Box 12 Folder 22
119 - In Vitro Selection of Qß Ribonucleic Acid Variants Resistant to Ethidium Bromide. With R. Saffhill, et al, 1970
Box 12 Folder 23
120 - Studies in Prebiotic Synthesis. VI. Synthesis of Propiolaldehyde and Nicotinamide. With Michael J. Dowler, et al, 1970
Box 12 Folder 24
121 - The Maintenance of the Accuracy of Protein Synthesis and Its Relevance to Ageing: A Correction, 1970
Box 12 Folder 25
122 - Template Catalysis of Acetyl Transfer Reactions. With Nancy M. Chung and R. Lohrmann, 1971
Box 12 Folder 26
123 - Urea-Inorganic Phosphate Mixtures as Prebiotic Phosphorylating Agents. With R. Lohrmann, 1971
Box 12 Folder 27
124 - The Mechanism of the Trimetaphosphate-Induced Peptide Synthesis. With Nancy M. Chung, et al, 1971
Box 13 Folder 1
125 - Catalysts for the Polymerization of Adenosine Cyclic 2',3'-Phosphate on a Poly(U) Template. With M. Renz and R. Lohrmann, 1971
Box 13 Folder 2
128 - Prebiotic Phosphorylation of Thymidine at 65° C in Simulated Desert Conditions. With M.J. Bishop and R. Lohrmann, 1972
Box 13 Folder 3
129 - Studies in Prebiotic Synthesis. VI. Synthesis of Purine Nucleosides. With William D. Fuller and Robert A. Sanchez, 1972
Box 13 Folder 4
130 - Polyphosphate and Trimetaphosphate Formation Under Potentially Prebiotic Conditions. With Ragnar Osterberg, 1972
Box 13 Folder 5
131 - Studies in Prebiotic Synthesis. VII. Solid-State Synthesis of Purine Nucleosides. With William D. Fuller and Robert A. Sanchez, 1972
Box 13 Folder 6
132 - A Possible Step in the Origin of the Genetic Code, 1972
Box 13 Folder 7-9
133 - The Origins of Life: Molecules and Natural Selection (1973)

Includes figures and photographs.

Box 13 Folder 10
134 - Struvite and Prebiotic Phosphorylation. With G.J. Handschuh, 1973
Box 13 Folder 11
135 - An RNA that Multiplies Indefinitely with DNA-Dependent RNA Polymerase: I. Selection from a Random Copolymer. With Christof K. Biebricher, 1973
Box 13 Folder 12
136 - Further Studies of Urea-Catalyzed Phosphorylation Reactions. With R. Osterberg and R. Lohrmann, 1973
Box 13 Folder 13-14
137 - Directed Panspermia. With F.H.C. Crick, 1973
Box 13 Folder 15
139 - Ageing of Clones of Mammalian Cells, 1973
Box 14 Folder 1
140 - Prebiotic Activation Processes. With R. Lohrmann, 1973
Box 14 Folder 2
141 - The Effect of Mg2+ and Ca2+ on Urea-Catalyzed Phosphorylation Reactions. With G.J. Handschuh and R. Lohrmann, 1973
Box 14 Folder 3
142 - Catalysts for the Self-Polymerization of Adenosine Cyclic 2',3'-Phosphate. With M.S. Verlander and R. Lohrmann, 1973
Box 14 Folder 4
143 - Analysis of High Molecular Weight Material from the Polymerization of Adenosine Cyclic 2',3'-Phosphate. With M.S. Verlander, 1974
Box 14 Folder 5
144 - The Origins of Life on the Earth (with Stanley L. Miller, 1974)
Box 14 Folder 6
145 - On the Possible Role of Crystals in the Origins of Life. VII. The Adsorption and Polymerization of Phosphoramidates by Montmorillonite Clay. With F.G. Burton and R. Lohrmann, 1974
Box 14 Folder 7
146 - Sedimentary Minerals Under Reducing Conditions, 1974
Box 14 Folder 8
147 - Prebiotic Chemistry and Nucleic Acid Replication. With R. Lohrmann, 1974
Box 14 Folder 9
149 - Poly(U)-Directed Transamidation Between Adenosine 5'-Phophorimidazolide and 5'-Phosphoadenosine 2'(3')-Glycine Ester. With Jaewon L. Shim and Rolf Lohrmann, 1974
Box 14 Folder 10
150 - Oligonucleotide Synthesis Catalyzed by the Zn2+ Ion. With Hiroaki Sawai, 1975
Box 14 Folder 11
151 - Prebiotic Peptide-Formation in the Solid State. I. Reactions of Benzoate Ion and Glycine with Adenosine 5'-Phosphorimidazolide. With R. Lohrmann, et al, 1975
Box 14 Folder 12
152 - Triple Helices Formed by Polyuridylic Acid With Some Adenosine Derivatives. With J.L. Shim and R. Lohrmann, 1975
Box 14 Folder 13
153 - Prebiotic Peptide-Formation in the Solid State. II. Reaction of Glycine with Adenosine 5'-Triphosphate and P1,P2-Diadenosine-Pyrophosphate. With H. Sawai and R. Lohrmann, 1975
Box 14 Folder 14
154 - Prebiotic Peptide-Formation in the Solid State. III. Condensation Reactions of Glycine in Solid State Mixtures Containing Inorganic Polyphosphates. With H. Sawai, 1975
Box 14 Folder 15
155 - ß-Structure of Alternating Polypeptides and Their Possible Prebiotic Significance. With André Brack, 1975
Box 14 Folder 16
156 - Prebiotic Polynucleotides and Polypeptides, 1975
Box 14 Folder 17
158 - N,N-Carbonyldiimidazole-Induced Peptide Formation in Aqueous Solution. With K.W. Ehler, 1976
Box 14 Folder 18
159 - Polymerization of Nucleotide Analogues. I. Reaction of Nucleoside 5'-Phosphorimidazolides with 2'-Amino-2'-Dexoyuridine. With R. Lohrmann, 1976
Box 14 Folder 19
160 - Template-Directed Synthesis of High Molecular-Weight Polynucleotide Analogues. With R. Lohrmann, 1976
Box 14 Folder 20
161 - Triple Helices Formed by Polyuridylic Acid with Some Amino Deoxyadenosine Derivatives. With Don E. Gibbs, 1976
Box 14 Folder 21
162 - Search for Organic and Volatile Inorganic Compounds in Two Surface Samples from the Chryse Planitia of Mars, 1976
Box 14 Folder 22
163 - N,N-Carbonyldiimidazole-Induced Deketopiperazine Formation in Aqueous Solution in the Presence of Adenosine-5'-Monophosphate. With A. Brack and K.W. Ehler, 1976
Box 14 Folder 23
164 - Some 5'-Azido and 5'-Amino-2'-Deoxyribonucleosides, Their 3'-Phosphates, and Their 3"-Phosphoimidazolides. With Don E. Gibbs, 1976
Box 14 Folder 24
165 - Reactions of Polyfunctional Amino Acids with N',N'-Carbonyldiimidazole in Aqueous Solution - Oligopeptide Formation. With K.W. Ehler and E. Girard, 1977
Box 15 Folder 1
166 - ß-Turns and the Evolution of Protein Synthesis, 1977
Box 15 Folder 2
167 - Reactions of Adenosine 5'-Phosphorimidazolide with Adenosine Analogues on a Polyuridylic Acid Template: The Uniqueness of the ß-Riboside. With R. Lohrmann, 1977
Box 15 Folder 3
168 - Template-Directed Reactions of Aminonucleosides. With R. Lohrmann, 1977
Box 15 Folder 4
169 - Gene-Duplication and the Origin of Proteins with Novel Functions, 1977
Box 15 Folder 5
170 - The Search for Organic Substances and Inorganic Volatile Compounds in the Surface of Mars. With K. Biemann, et al, 1977
Box 15 Folder 6
171 - Template-Directed Polynucleotide Condensation as a Model for RNA Replication. With R. Lohrmann, 1978
Box 15 Folder 7
172 - Preferential Formation of (2'-5')-Linked Internucleotide Bonds in Non-Enzymatic Reactions. With R. Lohrmann, 1978
Box 15 Folder 8
173 - Formation of P1,P2-Dinucleoside 5'-Pyrophosphates Under Potentially Prebiological Conditions. With R. Lohrmann, 1978
Box 15 Folder 9
174 - Amino Acid Activation with Adenosine 5'-Phosphorimidazole. With A.L. Weber, 1978
Box 15 Folder 10
175 - Phosphorylation of Nucleosides in Aqueous Solution Using Trimetaphosphate: Formation of Nucleoside Triphosphate. With Elisabeth Etaix, 1978
Box 15 Folder 11
176 - Formation of the Imidazolides of Dinucleotides Under Potentially Prebiotic Conditions. With H.L. Sleeper and R. Lohrmann, 1978
Box 15 Folder 12
177 - The Formation of Peptides from the 2'(3')-Glycyl Ester of a Nucleotide. With Arthur L. Weber, 1978
Box 15 Folder 13
178 - Heteropolynucleotides as Templates for Non-Enzymatic Polymerizations. With J. Ninio, 1978

A prior version titled "Template-Directed Condensation in Oligoadenylic Acids" is located in Series 3B.

Box 15 Folder 14
179 - Studies of Oligoadenylate Formation on a Poly(U) Template. With R. Lohrmann, 1979
Box 15 Folder 15
180 - The Catalysis of Nucleotide Polymerization by Compounds of Divalent Lead. With H.L. Sleeper, 1979
Box 15 Folder 16
181 - Selection in vitro , 1979
Box 15 Folder 17
182 - The Formation of Dipeptides from Amino Acids and the 2'(3')-Glycyl Ester of an Adenylate. With Arthur L. Weber, 1979
Box 15 Folder 18
183 - The Formation of Peptides from Glycine Thioesters. With Arthur L. Weber, 1979
Box 15 Folder 19
184 - Template-Directed Synthesis of Oligoadenylates Catalyzed by Pb2+ Ions. With H.L. Sleeper and R. Lohrmann, 1979
Box 15 Folder 20
185 - Self-Condensation of Activated Dinucleotides on Polynucleotide Templates with Alternating Sequences. With R. Lohrmann, 1979
Box 16 Folder 1-3
186 - Selfish DNA: The Ultimate Parasite. With F.H.C. Crick, 1980
Box 16 Folder 4
188 - Efficient Metal-Ion Catalyzed Template-Directed Oligonucleotide Synthesis. With R. Lohrmann, 1980
Box 16 Folder 5
189 - Template-Directed Synthesis and Selective Adsorption of Oligoadenylates on Hydroxyapatite. With D. Gibbs and R. Lohrmann, 1980
Box 16 Folder 6
190 - Poly(U)-Directed Peptide-Bond Formation from the 2'(3')-Glycyl Ester of Adenosine Derivatives. With Arthur L. Weber, 1980
Box 16 Folder 7
191 - Efficient Catalysis of Poly(C)-Directed Oligoguanylate Formation by Pb2+. With R. Lohrmann, 1980
Box 16 Folder 8
192 - Catalysis of Accurate Poly(C)-Directed Synthesis of 3'-5'-Linked Oligoguanylates by Zn2+. With P.K. Bridson, 1980
Box 16 Folder 9
193 - Template-Directed Synthesis of Oligoguanylic Acids - Metal Ion Catalysis. With P.K. Bridson, et al, 1981
Box 16 Folder 10
194 - Template-Directed Synthesis of Oligoguanylates in the Presence of Metal Ions. With J.H.G. van Roode, 1980
Box 16 Folder 11
196 - The Effect of Poly(C) on the Formation of Peptide Bonds from the 2'(3')-Gycyl Ester of a Guanosine Nucleotide. With Arthur L. Weber, 1981
Box 16 Folder 12
197 - The Synthesis of Oligoguanylates on Oligocytidylate Templates. With H. Fakhrai and J.H.G. van Roode, 1981
Box 16 Folder 13
198 - Condensation of Activated Diguanylates on a Poly(C) Template. With R. Lohrmann and P.K. Bridson, 1981
Box 16 Folder 14
199 - Substituent Control of the Poly(C)-Directed Oligomerization of Guanosine 5'-Phosphoroimidazolide. With Tan Inoue, 1981
Box 16 Folder 15
200 - Template Directed Reactions of 2-Aminoadenylic Acid Derivatives. With Thomas R. Webb, 1982
Box 16 Folder 16
201 - Oligomerization of (Guanosine 5'-Phosphor)-2-Methylimidazolide on Poly(C): An RNA Polymerase Model. With T. Inoue, 1982
Box 16 Folder 17
202 - Darwinism At the Very Beginning of Life, 1982
Box 16 Folder 18
203 - A Non-Enzymatic RNA Polymerase Model, 1983
Box 16 Folder 19
204 - The Origin of Life and the Evolution of Macromolecules, 1983
Box 17 Folder 1
205 - Derivation of Unprotected Polynucleotides. With Barbara C.F. Chu and Geoffrey M. Wahl, 1983
Box 17 Folder 2
206 - Temperature-Dependence of the Template-Directed Synthesis of Oligoguanylates. With Habib Fakhrai and Tan Inoue, 1984
Box 17 Folder 3
207 - Preparation of Ligation Intermediates and Related Polynucleotide Pyrophosphates. With Barbara C.F. Chu, 1984
Box 17 Folder 4
208 - Non-Enzymatic Template-Directed Synthesis on RNA Random Copolymers. I. Poly(CU) Templates. With G.F. Joyce and T. Inoue, 1984
Box 17 Folder 5
209 - Chiral Selection in Poly(C)-Directed Synthesis of Oligo(G). With G.F. Joyce, et al, 1984
Box 17 Folder 6
210 - Template-Directed Synthesis on the Pentanucleotide CpCpGpCpC. With T. Inoue, et al, 1984
Box 17 Folder 7
211 - Template-Directed Synthesis with 2-Aminoadenosine. With Kazimierz Grzeskowiak and Thomas R. Webb, 1984
Box 17 Folder 8
212 - Non-Enzymatic Sequence-Specific Cleavage of Single-Stranded DNA (Ethylenediaminetetraacetic Acid Adduct/Oligodeoxynucleotide/Hybridization). With Barbara C.F. Chu, 1985
Box 17 Folder 9
213 - Oligomerization of Activated Derivatives of 3'-Amino-3'-Deoxyguanosine on Poly(C) and Poly(dC) Templates. With Wojciech S. Zielinski, 1985
Box 17 Folder 10
214 - Template-Directed Synthesis of Oligodeoxycytidylate and Polydeoxycytidylate Templates. With C.B. Chen and T. Inoue, 1980
Box 17 Folder 11
215 - Template-Directed Synthesis of Novel, Nucleic Acid-Like Structures. With Alan W. Schwartz, 1985
Box 17 Folder 12
217 - Template-Directed Polynucleotide Synthesis on Mineral Surfaces. With Alan W. Schwartz, 1985

Letter to the editor.

Box 17 Folder 13
218 - Detection of Specific DNA Sequences with Short Biotin-Labeled Probes. With Barbara C.F. Chu, 1985
Box 18 Folder 1
220 - Template-Directed Synthesis on the Oligonucleotide d(C7-G-C7). With Tomasz Haertle, 1986
Box 18 Folder 2
221 - Non-Enzymatic Template-Directed Synthesis on RNA Random Copolymers: Poly(C,G) Templates. With G.F. Joyce, 1986
Box 18 Folder 3
222 - The Template Properties of Some Oligodeoxynucleotides Containing Cytidine and Guanosine. With Tomasz Haertle, 1986
Box 18 Folder 4
223 - Template-Directed Oligonucleotide Ligation on Hydroxylapatite: An Analogue of Solid Phase Synthesis. with Oscar L. Acevedo, 1986
Box 18 Folder 5
224 - Synthesis of an Amplifiable Reporter RNA for Bioassays. With Barbara C.F. Chu and Fred Russell Kramer, 1986
Box 18 Folder 6
225 - Molecular Replication and the Origins of Life, 1986
Box 18 Folder 7
226 - Template-Directed Synthesis on Short Oligoribocytidylates. With Kazimierz Grzeskowiak, 1986
Box 18 Folder 8
227 - How Mistakes Are Made. Review of Accuracy in Molecular Processes: Its Control and Relevance in Living Systems (T.B.L. Kirkwood, R.F. Rosenberger and D.J. Galas, editors, 1986), 1986
Box 18 Folder 9
228 - Did Template-Directed Nucleation Precede Molecular Replication?, 1986
Box 18 Folder 10-11
229 - RNA Catalysis and the Origins of Life, 1986
Box 18 Folder 12
230 - Oligoaminonucleoside Phosphoramidates. Oligomerization of Dimers of 3'-Amino-3'-Deoxynucleotides (GC and CG) in Aqueous Solution. With Wojciech S. Zielinski, 1987
Box 18 Folder 13
231 - The Action of a Water-Soluble Carbodiimide on Adenosine-5'--Polyphosphates. With Kam-mui Eva Ng, 1987
Box 19 Folder 1
232 - Autocatalytic Synthesis of a Tetranucleotide Analogue. With Wojciech S. Zielinski, 1987
Box 19 Folder 2
233 - Oligomerization of 3'-Amino-3'-Deoxyguanosine-5'-Phosphorimidazolidate on a d(CpCpCpCpC) Template. With Mary Tohidi, et al
Box 19 Folder 3
234 - The Case for an Ancestral Genetic System Involving Simple Analogues of the Nucleotides. With Gerald F. Joyce, et al, 1987
Box 19 Folder 4
235 - Impressions of the LII Cold Spring Harbor Symposium on Quantitative Biology, "The Evolution of Catalytic Function", 1987
Box 19 Folder 5
236 - Non-Enzymatic Transcription of an Oligodeoxynucleotide 14 Residues Long. With Oscar L. Acevedo, 1987
Box 19 Folder 6
237 - Evolution of the Genetic Apparatus: A Review, 1987
Box 19 Folder 7
238 - The Origin of Self-Replicating Molecules, 1987
Box 19 Folder 8
239 - Template-Directed Oligomerization of 3-Isoadenosine 5'-Phosphate. With Aubrey R. Hill, et al, 1988
Box 19 Folder 9
240 - Ligation of Oligonucleotides to Nucleic Acids or Proteins via Disulfide Bonds. With Barbara C.F. Chu, 1988
Box 19 Folder 10
241 - Non-Enzymatic Template-Directed Synthesis on RNA Random Copolymers: Poly(C,A) Templates. With G.F. Joyce, 1988
Box 19 Folder 11
242 - Cyclization of Nucleotide Analogues as an Obstacle to Polymerization. With Aubrey R. Hill, Jr., et al, 1989

Letter to the editor.

Box 19 Folder 12
243 - Some Acyclic Analogues of Nucleotides and Their Template-Directed Reactions. With Mahrokh Tohidi, 1989
Box 19 Folder 13
245 - Reaction on Alternating GC Oligonucleotide Templates. With K-m. E. Ng, 1989
Box 19 Folder 14
246 - Replacement of the 3'-CH Group by Nitrogen in the Carbocylic Analogue of Thymidine. With Kam-mui Eva Ng, 1989
Box 19 Folder 15
247 - Was RNA the First Genetic Polymer?, 1989
Box 20 Folder 1
248 - Template Properties of Tetranucleoside Triphosphoramidates Having Cytosine-Guanosine Residues. With Wojciech S. Zielinski, 1989
Box 20 Folder 2
249 - Polymerization of a Monomeric Guanosine Derivative in a Hydrogen-Bonded Aggregate, 1989
Box 20 Folder 3
250 - The Origin of Polynucleotide-Directed Protein Synthesis, 1989
Box 20 Folder 4
251 - Polymerization of the Cyclic Pyrophosphates on Nucleosides and Their Analogues. With Mahrokh Tohidi, 1990
Box 20 Folder 5
251A - Nucleic Acids: Adding to the Genetic Alphabet, 1990
Box 20 Folder 6
252 - A Simple Procedure for Cross-Linking Complementary Oligonucleotides. With B.C.F. Chu, 1990
Box 20 Folder 7
253 - Polymerization of Amino Acids Containing Nucleotide Bases. With Azzouz Ben Cheikh, 1990
Box 20 Folder 8
255 - Blunt-End and Single-Strand Ligation by Escherichia coli Ligase: Influence on an In Vitro Amplification Scheme. With Kevin J. Barringer, et al, 1990
Box 20 Folder 9
257 - Synthesis of 5'-Deoxy-5'-Nucleosideacetic Acid Derivatives. With Kazuo Harada, 1990
Box 20 Folder 10
258 - Pyrophosphate-Formation As the Most Efficient Condensation Reaction of Activated Nucleotides. With Libaniel Rodriguez, 1991
Box 20 Folder 11
259 - Disulfide-Linked Oligonucleotide Phosphorothioates: Novel Analogues of Nucleic Acids. With Taifeng Wu, 1991
Box 20 Folder 12
260 - Acceleration of the Template-Directed Reactions of Nucleoside 5'-Phosphorimidazolides by Acylation. With Libaniel Rodriguez, 1991
Box 20 Folder 13
261 - The Cyclization of Arabinosyladenine-5'-Phosphorimidazolide. With Kazuo Harada, 1991
Box 20 Folder 14
262 - Which 3-Ribofuranosyl-Substituted Purine 5'-Phosphates Undergo Template-Directed Oligomerization? With Aubrey R. Hill, Jr., et al, 1991
Box 20 Folder 15
263 - Template-Directed Extension of a Guanosine 5'-Phosphate Covalently Attached to an Oligodeoxycytidylate Template. With Libaniel Rodriguez, 1991
Box 20 Folder 16
264 - Photooxidation of Oligodeoxynucleotides by UO2 2+. With Aubrey R. Hill, Jr., 1991
Box 21 Folder 1
265 - An Efficient Sequence-Specific Method for Crosslinking Complementary Oligonucleotides Using Binuclear Platinum Complexes. With Eric S. Gruff, 1991

Unpublished

Box 21 Folder 2
Existence of Self-Reproducing Units, 1964 - 1965
Box 21 Folder 3
Oligomerization of Dimers of 3'-Amino-3'-Deoxynucleotides Having Complementary AC and GU Sequences. With Wojciech S. Zielinski, 1988
Box 21 Folder 4
Poly(dC) as a Template for Non-Enzymatic Oligo(G) Synthesis. With Tan Inoue
Box 21 Folder 5
Polymerization of a Monomeric Guanosine Derivative in a Hydrogen Bonded Aggregate. With Wojciech S. Zielinski, 1988
Box 21 Folder 6-7
Template-Directed Condensation of Oligoadenylic Acids. With Jacques Ninio, 1976 - 1977

The published version of this paper is located in Series 3A: 178 - Heteropolynucleotides as Templates for Non-Enzymatic Polymerizations.

Box 21 Folder 8
Thermal Synthesis of Oligourdylates at Moderate Temperatures. With Ragnar Osterberg and Rolf Lohrmann

CONTRACTS, GRANTS AND PROPOSALS

Scope and Content of Series

SERIES 4) CONTRACTS, GRANTS AND PROPOSALS: Correspondence, proposals, contracts, figures, and budget information for Orgel's research projects. Arranged by sponsoring agency in four subseries: A) National Aeronautics and Space Administration (NASA), B) National Institutes of Health (NIH), C) National Science Foundation (NSF), and D) U.S. Army.

A) National Aeronautics and Space Administration (NASA): Includes materials on the photochemical generation of prebiotic condensing agents, molecular analysis for the 1975 Viking Mars Lander missions, and RNA polymerase models.

B) National Institutes of Health (NIH): Includes Orgel's research projects on the evolution of genetic specificity and nucleic acid analogs.

C) National Science Foundation (NSF): Research projects in prebiotic chemistry, biochemical evolution, and template-directed synthesis.

D) U.S. Army: A research proposal for sequence-specific inactivation of m-RNA.

National Aeronautics and Space Administration

Box 21 Folder 9-10
Photochemical Generation of Prebiotic Condensing Agents, 1965 - 1969
Box 21 Folder 11-12
Models for the Generation of Prebiotic Condensing Agents, 1970 - 1971
Box 21 Folder 13
Participation in the Science Planning for the Viking 1975 Missions in the Area of Molecular Analysis, 1970
Box 22 Folder 1-2
Participation in the Science Planning for the Viking 1975 Missions in the Area of Molecular Analysis, 1971 - 1980
Box 22 Folder 3-12
Models for the Generation of Prebiotic Condensing Agents, 1972 - 1984
Box 22 Folder 13
RNA Polymerase Models, 1982
Box 23 Folder 1-4
Models for the Generation of Prebiotic Condensing Agents, 1985 - 1988
Box 23 Folder 5
Prebiotic Template-Directed Synthesis, 1985

National Institutes of Health

Box 23 Folder 6-7
Evolution of Genetic Specificity, 1965 - 1968
Box 23 Folder 8
Nucleic Acid Analogs - Synthesis and Chemotherapy, 1971 - 1974
Box 24 Folder 1-4
Evolution of Genetic Specificity, 1975 - 1987

National Science Foundation

Box 24 Folder 5-6
Study of Biochemical Evolution, 1964 - 1969
Box 24 Folder 7
Prebiotic Activation of Amino Acids and Nucleotide Bases, 1973 - 1978
Box 25 Folder 1
Prebiotic Formation of Peptide Bonds, 1978 - 1979
Box 25 Folder 2
A Non-Classical System of Template-Directed Synthesis, 1981 - 1983
Box 25 Folder 3-5
Template-Directed Synthesis with 3'-Amino 3'-Deoxynucleotides, 1982 - 1989

United States Army

Box 25 Folder 6
Sequence-Specific Inactivation of m-RNA, 1985 - 1986

CONFERENCES AND MEETINGS

Scope and Content of Series

Series 5) CONFERENCES AND MEETINGS: Correspondence, programs, speaker lists, notes, and drafts of talks given by Orgel at scientific conferences, symposia, and seminars. Includes lists of meetings that Orgel attended. Arranged chronologically.

Box 25 Folder 7
Lists of meetings attended: 1975-1977, 1981-1985
Box 25 Folder 8
First Soviet American Conference on Communication with Extraterrestrial Intelligence (CETI). Armenian Academy of Sciences, 1971 September 5-11

1967 October 20: A series of "Telesnaps" photographs from a British Broadcasting Corporation program, numbered.

Box 25 Folder 9
Quatrième Conférence Internationale de la Physique Théorique à la Biologie. Paris, 1973 May 28

Includes correspondence in French.

Box 25 Folder 10
Some Aspects of Pre-Biotic Chemistry - Some Theories of Ageing (and the Evidence). Cornell University Special Lectures, 1975 February 27-28
Box 25 Folder 11
Symposium on Nucleic Acid Replication. Montebello, Québec, 1975 March 2-7
Box 25 Folder 12
Fourth Annual Workshop on the Biology of Aging - Perspectives in Theories of Biological. Scripps Institution of Oceanography, 1975 March 23-25
Box 25 Folder 13
Polymerization and Polycondensation on Clays - Their Role in Abiotic Synthesis and the Origin of Life. Polytechnic Institute of New York, 1975 May 23
Box 26 Folder 1-2
European Molecular Biology Organization workshop, Barcelona, 1975 May 26-28

Contains letters by Carl Sagan (1/17/75) and Severo Ochoa (11/21/74).

Box 26 Folder 3
Viking Science Symposium on Earth and Mars - The Role of Life, Kennedy Space Center, 1975 August 7-11
Box 26 Folder 4
Prebiotic Synthesis of Nucleotides and Polynucleotides, Ames Research Center, 1975 August 13
Box 26 Folder 5
Chemistry Colloquium, Department of Chemistry, Purdue University, 1975 October 22
Box 26 Folder 6
Evans Lecture, Ohio State University Chemistry Department, 1975 October 24
Box 26 Folder 7
Towards Self-Replicating Molecules. Texas A and M University, College of Agriculture, 1975 October 28
Box 26 Folder 8
Robert A. Welch Foundation Conferences on Chemical Research. XIX: Photon Chemistry, Houston, 1975 October 29-31
Box 26 Folder 9
Bio-Cultural Concepts of Man, Fullerton College, 1975 November 19
Box 26 Folder 10
Discussion Colloquium on the Biology of Religion. Institute for Higher Studies, Santa Barbara, 1975 December 3-4
Box 26 Folder 11
Gordon Research Conference on the Biology of Aging, Santa Barbara, 1976 January 25-30
Box 26 Folder 12
Lectures on Chemical Evolution. Stanford University Medical Center, 1976 February 6
Box 26 Folder 13
Science and Our Expectations - Bicentennial and Beyond. American Association for the Advancement of Science, Boston, 1976 February 18-24

Contains letter by Carl Sagan (10/17/75).

Box 26 Folder 14
Viking Molecular Analysis Team. Jet Propulsion Laboratory, Pasadena, 1976 March 18-19
Box 26 Folder 15
Genetics Seminar, Salk Institute - Origin of Self-Replicating Material, 1976 April 6
Box 26 Folder 16
Viking Project. Jet Propulsion Laboratory - Viking Flight Team Memorandum, 1976 April 9-10
Box 26 Folder 17
Renaud Lectures. Michigan State University, Department of Biochemistry, 1976 April 19-20
Box 26 Folder 18
Organization and Expression of the Eukaryotic Genome, Portsmouth, U.K., 1976 May 3-6
Box 26 Folder 19
Langley Colloquium Series, Hampton, Virginia, 1976 June 28
Box 26 Folder 20
Present State of Viking Data. MIT Department of Chemistry, 1977 January 10-12
Box 26 Folder 21
Institute for Higher Studies seminar - A Fifty Year View, Santa Barbara, 1977 January 20-22
Box 26 Folder 22
United States Information Agency. Viking Science Tour, Paris, 1977 March 3-4:
Box 26 Folder 23
New Trends in Geriatric Care. UC San Diego School of Medicine, 1977 March 14
Box 26 Folder 24
Molecules and Evolution. International Lectures on Human, Global and Universal Problems. University of Stockholm, 1977 April 19-20
Box 26 Folder 25
Origin of Self-Replicating Molecules. California State University, Los Angeles, 1977 March 29
Box 26 Folder 26
Origins of Life Festival. University of Oregon, Institute of Molecular Biology, 1977 May 16
Box 26 Folder 27
Viking Science Steering Group meeting, Jet Propulsion Laboratory, 1977 June 28-29
Box 26 Folder 28
Current Biological Problems - A School for Physical Scientists, Seattle, 1977 July 15-16
Box 26 Folder 29
International Summer School on Genome Organization and Function, Spetsai, Greece, 1977 August 21 - September 3
Box 26 Folder 30
Seminar - California Institute of Technology, Division of Biology, 1977 October 17
Box 26 Folder 31
A Conversation About the Origins of Life. Friends of the International Center, UC San Diego, 1977 November 8
Box 27 Folder 1
Seminar series, California State University, Long Beach, Department of Chemistry, 1977 November 16
Box 27 Folder 2
Science seminar, San Diego City College, Department of Chemistry, 1977 December 1
Box 27 Folder 3
Meeting of the Royal Society, London, 1978 December 6-7
Box 27 Folder 4
Conference on Selforganization in Living Systems, Drubrovnik, Yugoslavia, 1979 August 26-31
Box 27 Folder 5
The Evolution of Life - A Public Symposium, Toronto, 1979 October 25-26
Box 27 Folder 6
Fifth Science Workshop on the Origins of Life, Los Angeles, 1980 January 17-18
Box 27 Folder 7
American Institute of Biological Sciences. Planetary Biology Advisory Panel, Arlington, Virginia, 1980 February 4-5
Box 27 Folder 8
Prebiotic Chemistry - Nucleic Acids and the Origin of Self-Replication, UC Los Angeles, 1980 April 18
Box 27 Folder 9
Science Workshops on the Origins of Life, Rockefeller University, New York, 1980 April 24-25
Box 27 Folder 10
Monsanto Company Technical Management Conference - New Technology Horizons, St. Louis, 1980 May 20-21
Box 27 Folder 11
Workshop on Molecular Evolution and Function of Three Dimensional Structure in Nucleic Acids and Proteins, University of Stockholm, 1980 June 16-17
Box 27 Folder 12
International Society for the Study of the Origins of Life Conference, Jerusalem, 1980 June 23-27
Box 27 Folder 13
Pomona College Dreyfus Seminar Series, Claremont, 1980 September 25
Box 27 Folder 14
Seminar, Massachusetts Institute of Technology, 1980 September 30
Box 27 Folder 15
Caltech Centennial Symposium - The Chemical Bond Structure and Dynamics, Pasadena, 1981 February 28
Box 27 Folder 16
Towards an RNA Polymerase Model, UC Los Angeles School of Medicine, 1981 March 4
Box 27 Folder 17
Contemporary Issues Undergraduate Seminar. Origins of Life in the Ocean? UC San Diego, 1981 March 31
Box 27 Folder 18
Genome Evolution and Phenotype Variation. University of Cambridge Genome Meeting, 1981 June 22-24
Box 27 Folder 19
Dalhousie Symposium on the Evolution of the Eukaryotic Genome and Its Components, Halifax, 1981 July 12-15
Box 27 Folder 20
Organizing and planning meeting for Workshops on Exobiology in the Exploration of the Solar System, Ames Research Center, 1981 August 3-4
Box 27 Folder 21
European Molecular Biology Organization Workshop on Accuracy, Grignon, France, 1981 September 1-6
Box 27 Folder 22
Max Planck Institute, Göttingen, 1981 September 6-9
Box 27 Folder 23
California Catalysis Society fall meeting, La Jolla, 1981 October 24-25
Box 27 Folder 24
Committee on Planetary Biology and Chemical Evolution - Space Science Board, Washington, D.C., 1981 December 7-8
Box 27 Folder 25
Workshop on Exobiology in Solar System Exploration, Ames Research Center, 1981 December 9-11
Box 27 Folder 26
City of Hope Research Institute seminar, Duarte, California, 1982 February 2
Box 27 Folder 27
Gordon Conference on Metals in Biology, Ventura, 1982 February 8-12
Box 27 Folder 28
Biophysical/Physical Chemistry seminar. UC Berkeley Chemistry Department, 1982 March 16
Box 27 Folder 29
Life Sciences Advisory Committee meeting. Exobiology Program review, Ames Research Center, 1982 March 20
Box 27 Folder 30
Space Science Board. Committee on Planetary Biology and Chemical Evolution, Santa Barbara, 1982 March 25-28
Box 27 Folder 31
Exobiology Program review, NASA Life Sciences Advisory Committee, Ames Research Center, 1982 April 12
Box 27 Folder 32
Origin and Evolution of Life. Tufts University, Sackler School of Graduate Biomedical Sciences, Boston, 1982 April 28
Box 27 Folder 33
Committee on Space Science Research, 24th plenary meeting - Chemical Evolution and the Origins of Life, Ottawa, 1982 May 17-June 3
Box 28 Folder 1
Darwin Centenary Conference. Cambridge, UK, 1982 June 27-July 2
Box 28 Folder 2
Gordon Conference on the Origin of Life, New London, NH, 1982 July 19-23
Box 28 Folder 3
First Symposium on Chemical Evolution and the Origin and Evolution of Life, Ames Research Center, 1982 August 2-4
Box 28 Folder 4
The Past, Present and Future of Genetics. Brno, Czechoslovakia, 1982 August 26-September 1
Box 28 Folder 5
Nobel Symposium on Inorganic Biochemistry, Sweden, 1982 September 5-10
Box 28 Folder 6
U.S.-Japan Cooperative Seminar on Pathogenic Mechanisms in Werner's Syndrome and Their Role in Human Aging, Kobe, 1982 December 10-12
Box 28 Folder 7
Gerontology Research Center Seminar. A Non-Enzymatic RNA Polymerase Model, Baltimore, 1983 February 22
Box 28 Folder 8
Space Science Board, Committee on Planetary Biology, Washington, D.C., 1983 February 23-25
Box 28 Folder 9
American Association for the Advancement of Science. Science and Engineering - Toward a National Renaissance, Detroit, 1983 May 26-31
Box 28 Folder 10
7th International Conference on the Origins of Life and 4th Meeting of the International Society for the Study of the Origin of Life, Mainz, Germany, 1983 July 10-15
Box 28 Folder 11
Third Workshop on Exobiology in Solar System Exploration, Ames Research Center, 1983 August 25-26
Box 28 Folder 12
Conference on Biomaterials, American Academy of Arts and Sciences, Cambridge, MA, 1983 September 19-20
Box 28 Folder 13
Attempts to Imitate RNA Polymerase, University of Southern California, Los Angeles, 1983 October 14
Box 28 Folder 14
Attempts to Develop a Nonenzymatic RNA Polymerase. California State University, Los Angeles, 1983 October 18
Box 28 Folder 15
Pacific Conference on Chemistry and Spectroscopy. Origin of Life Symposium, Pasadena, 1983 October 26-28
Box 28 Folder 16
Organization, Replication and Evolution of Early Macromolecules, Orléans, France, 1985 February 7
Box 28 Folder 17
Chemische Gesellschaft Zürich, 1985 February 13
Box 28 Folder 18
City of Hope, Duarte, CA, 1985 April 12
Box 28 Folder 19
Primary Structure Conformation and Evolution of Nucleic Acids and Proteins. Accademia Nazionale dei Lincei, Rome, 1985 May 2-4

Includes photograph of Giorgio Bernardi.

Box 28 Folder 20
Fourth Conversation in the Discipline - Biomolecular Stereodynamics. State University of New York at Albany, 1985 June 4-8
Box 28 Folder 21
2nd Symposium on Chemical Evolution and the Origin and Evolution of Life, Ames Research Center, 1985 July 23-26
Box 28 Folder 22
Niels Bohr Centenary Symposium, Copenhagen, 1985 October 4-7
Box 28 Folder 23
Symposium on the Origin of Life, Caltech, Pasadena, 1985 October 14-15

Contains photograph of birthday cake, "70 Happy Birthday Norm 70."

Box 28 Folder 24
Seminar program. University of California, Davis, Department of Zoology, 1985 November 12
Box 28 Folder 25
Annual meeting of the Gerontology Society of America, New Orleans, 1985 November 22-26
Box 28 Folder 26
Bureau of Biological Research 50th Anniversary Symposium - A Molecular View of Evolution. Rutgers University, Piscataway, NJ, 1986 May 15
Box 28 Folder 27
22nd Winter Seminar on Molecules, Information and Memory, Klosters, Switzerland, 1987 January 18-30
Box 28 Folder 28
Biochemistry Department lecture series. University of California, Berkeley, 1987 February 17
Box 28 Folder 29
Western Winter Workshop on the Evolution of Genes and Genomes, Lake Tahoe, 1987 March 4-7
Box 28 Folder 30
General Biology Seminar. California Institute of Technology, Division of Biology, 1987 April 28
Box 28 Folder 31
Significance of Chemical Templates in Studies on the Origin of Life. University of Toledo, 1987 May 4
Box 28 Folder 32
Evolution of Catalytic Function, Cold Spring Harbor Laboratory, 1987 May 27-June 3

Includes correspondence from James Watson.

Box 29 Folder 1
Symposium on the Bioorganic Chemistry of Enzymes and Nucleic Acids, Bellingham, WA, 1987 June 18-19
Box 29 Folder 2
Space Life Sciences Symposium. Three Decades of Life Science Research in Space, Washington, D.C., 1987 June 21-26
Box 29 Folder 3
Gordon Conference on the Origins of Life, Concord, NH, 1987 August 17-21
Box 29 Folder 4
Artificial Life - an Interdisciplinary Workshop on the Synthesis and Simulation of Living Systems, Los Alamos, 1987 September 21-25
Box 29 Folder 5
The Frontiers of Tomorrow in Biology, Hyderabad, 1987 November 19-26
Box 29 Folder 6
Gunter Sachs postdoctoral winter symposium. Genes and Development, La Jolla, 1988 January 14-15
Box 29 Folder 7
American Academy of Sciences annual meeting, Boston, 1988 February 12-14
Box 29 Folder 8
Royal Netherlands Chemical Society. Biennial symposium of the Organic Division, Wageningen, 1988 April 14-15
Box 29 Folder 9
9th Annual D.G. Davis Memorial Lecture. Molecular Replication and the Origin of Life, University of New Orleans, 1988 April 22
Box 29 Folder 10
Gordon Conference on Enzymes, Coenzymes and Metabolic Pathways, Meriden, NH, 1988 July 4-8
Box 29 Folder 11
International Summer School on Organization and Function of the Eukaryotic Genome, Spetsai, Greece, 1988 September 1-10
Box 29 Folder 12
196th American Chemical Society Meeting and Exposition, Los Angeles, 1988 September 25-30
Box 29 Folder 13
Template-Directed Synthesis of Oligonucleotides. UC Santa Cruz, 1988 October 24
Box 29 Folder 14
Applied Molecular Evolution and the Maturation of the Immune Response, Santa Fe, 1989 March 27-31
Box 29 Folder 15
Ida Bean Visiting Professor Lecture Series. University of Iowa, 1989 April 16-19
Box 29 Folder 16
Storer Life Sciences Symposium - Evolution of the Biosphere, UC Davis, 1989 May 8-11
Box 29 Folder 17
Cold Spring Harbor RNA Processing meeting, 1989 May 17-21
Box 29 Folder 18
6th International Society for the Study of the Origin of Life meeting and 9th International Conference on the Ninth International Conference on the Origin of Life, Prague, 1989 July 3-8
Box 29 Folder 19
25th Winter Seminar on Molecules, Information and Memory, Klosters, Switzerland, 1990 January 21-26
Box 29 Folder 20
Frontiers in Biomedical Research, Rancho Mirage, CA, 1990 February 4-8
Box 29 Folder 21
Lecture Series on Frontiers in Chemistry. Research Institute of Scripps Clinic, La Jolla, 1990 February 9
Box 29 Folder 22
Juan March Foundation Lectures on Molecular Biology, Madrid, 1990 March 5
Box 29 Folder 23
Biology Department seminar, Yale University, 1990 March 28
Box 29 Folder 24
Molecular Biology and the Origin of Life Symposium, Institute for Advanced Studies in Biology, Berkeley, 1990 July 15-18
Box 29 Folder 25
4th Symposium on Chemical Evolution and the Origin and Evolution of Life, Ames Research Center, 1990 July 24-27
Box 30 Folder 1
Catalytic RNA as an Anti-HIV Agent. Design and Delivery to Cells, San Diego, 1990 October 21-24
Box 30 Folder 2
Structural Biology seminar. UC Berkeley Chemistry Department, 1990 November 19
Box 30 Folder 3
Keystone Symposia on Molecular and Cellular Biology, Taos, 1991 February 2-8
Box 30 Folder 4
Tribute to Linus Pauling on his 90th Birthday, Caltech, 1991 February 28
Box 30 Folder 5
Evolution, Göttingen, 1991 April 22
Box 30 Folder 6
Bruno Zimm Symposium. UC San Diego, 1991 May 18
Box 30 Folder 7
American Chemical Society, San Diego Section, 1991 May 29

SUBJECT FILES

Scope and Content of Series

Series 6) SUBJECT FILES: Correspondence, grants, and proposals related to Orgel's and the Salk Institute's research on aging, including a proposed book on aging by Orgel and Robin Holliday; biographical information on Leslie Orgel, Carl Sagan, and John Griffith Stanley; photographs of Mars taken by the Viking Landers; and a sound recording on RNA sequencing. The series also includes correspondence and a table of contents for a proposed book about the RNA Tie Club, a 1950s society of researchers dedicated to understanding the genetic code. Original media is restricted; researchers may request listening copies in advance of their visit.

Box 30 Folder 8-9
Aging - Book on aging

Includes chapter on clonal aging.

Box 30 Folder 10-14
Aging - Correspondence, 1970 - 1981
Box 31 Folder 1-2
Aging - Correspondence , 1973 - 1984

Includes correspondence with publishers.

Box 31 Folder 3-5
Aging - Grants, 1972 - 1983

Includes grants applications to Fritz B. Burns Foundations, McConnell Clark Foundation, and the National Institute of Health.

Box 31 Folder 6-7
Aging - Salk Institute research programs, symposia and workshops, 1973 - 1974
Box 31 Folder 8
Biebricher, Christof, 1972 - 1976
Box 31 Folder 9
Griffith, John Stanley - Correspondence regarding his candidacy for the Royal Society, 1969
Box 31 Folder 10
Mars - Photographs from Viking 1 and 2 Landers, 1976
Box 31 Folder 11
Mulliken, Robert S., 1978 - 1985
Box 31 Folder 12
RNA sequencing - Reel-to-reel audio recording

Restrictions Apply

Box 31 Folder 13
RNA Tie Club - Book materials, 1953 - 1981

Includes correspondence (1953-1962) from George Gamow to James Watson and Alexander Rich. Also includes a detailed table of contents for proposed book.

Box 31 Folder 14
Sagan, Carl, 1991

Correspondence regarding Sagan's nomination to the National Academy of Sciences.

Box 32 Folder 1
University of California, San Diego - Chemistry Department, 1964 - 1980

Correspondence and biographical materials regarding Orgel's academic appointment at UC San Diego.

SALK INSTITUTE

Scope and Content of Series

Series 7) SALK INSTITUTE. Files documenting Orgel's association and interaction with the Salk Institute, arranged in six subseries: A) Chemical Evolution Laboratory, B) Faculty, C) Fellows, D) General, E) Salk Memoranda, and F) Salk Institute Biotechnology/Industrial Associates.

A) Chemical Evolution Laboratory: Annual scientific reports of the Chemical Evolution Laboratory, 1975-1980.

B) Faculty: Minutes of faculty meetings and senior resident faculty meetings, 1976– 1986.

C) Fellows: Annual reports, correspondence, and meeting minutes of the Fellows Committee, Operating Committee, and Space Committee, 1965–1977

D) General: Reports regarding laboratory and research activities, and staffing and publications, and information on the Sloan grant, 1970-1977.

E) Salk Memoranda: Memoranda from Jacob Bronowski, Frederic De Hoffmann and Edwin Lennox, 1965–1982.

F) Salk Institute Biotechnology/Industrial Associates: Files related to the commercial development of biotechnology research by Orgel and his associates, 1981-1988.

Chemical Evolution Laboratory

Box 32 Folder 2-4
Annual reports, 1975 - 1980

Faculty

Box 32 Folder 5
Faculty meetings, 1984 - 1986
Box 32 Folder 6
Senior resident faculty meetings, 1976 - 1982

Fellows

Box 32 Folder 7-8
Annual Report of the Director to the Fellows of the Salk Institute, 1971 - 1975
Box 32 Folder 9
Fellows Committee, 1970
Box 32 Folder 10
Operating Committee - Meeting minutes, 1970
Box 33 Folder 1
Resident Members of the Committee of Fellows - Meeting minutes, 1965
Box 33 Folder 2
Space Committee, 1977

General

Box 33 Folder 3
Sloan Grant, 1970
Box 33 Folder 4-5
Report of Laboratory and Research Activities, 1975 - 1977
Box 33 Folder 6
Report on Laboratory Staffing and Publications, 1976

Salk Memoranda

Box 33 Folder 7
Bronowski, Jacob, 1967 - 1974
Box 34 Folder 1-6
De Hoffmann, Frederic, 1970 - 1982
Box 34 Folder 7
Lennox, Edwin L., 1965 - 1974
Box 34 Folder 8
Salk business, 1965 - 1971
Box 35 Folder 1
Salk business, 1972 - 1975

Salk Institute Biotechnology/Industrial Associates

Box 35 Folder 2
Consultant nonstatutory stock option agreement, 1982
Box 35 Folder 3-8
Salk Institute Biotechnology/Industrial Associates, Inc. (SIBIA), 1981 - 1986
Box 36 Folder 1-2
Salk Institute Biotechnology/Industrial Associates, Inc. (SIBIA), 1987 - 1988
Box 36 Folder 3
Board of Trustees - Meeting minutes and by-laws, 1964

Accession Processed in 2018

BIOGRAPHICAL

Scope and Content of Series

Series 8) BIOGRAPHICAL: Biographical information for Leslie Orgel, including his appointment calendars, awards, interview transcripts and employment information for UC San Diego and the Salk Institute.

Box 37 Folder 1-5
Appointment calendars, 1997-2007
Box 37 Folder 6-7
Bibliographies, 1953-2006

Includes NASA, NIH, and NSF publications.

Box 37 Folder 8
Biographical information, 1974-2006
Box 37 Folder 9
Curricula vitae, 1985-2006
Oversize FB-208 Folder 1
Harrison Memorial Prize medal, 1956
Oversize AB-11-B07
Harold C. Urey medal and plaque, International Society for the Study of the Origin of Life (ISSOL), 1993
Box 37 Folder 10
Leslie Orgel and the Origin of Life. Orgel interviewed by Istvan Hargittai for The Chemical Intelligencer - Transcript and correspondence, 1997-1999
Box 37 Folder 11
Leslie Orgel interviewed by Brent Johnson and Robert Bradford for CSU Fullerton Center for Oral History - Transcript, 2004 May 18
Oversize FB-208 Folder 1
Mount Sinai School of Medicine medal
Box 37 Folder 12
Orgel, Hassia Alice - Curricula vitae, 1966
Oversize FB-208 Folder 1
Roussel Uclaf Tables Rondes medal. Comités scientifiques, dixième anniversaire, 1979
Box 38 Folder 1-3
Salk Institute - Employment and retirement, 1964-1983
Box 38 Folder 4
UC San Diego - Adjunct professor, 1985-2006
Box 38 Folder 5
UC San Diego - Leslie E. Orgel Distinguished Professorship in Inorganic Chemistry announcement, 2006

CORRESPONDENCE

Scope and Content of Series

Series 9) CORRESPONDENCE: Incoming and outgoing correspondence, particularly with chemists and molecular biologists, and with publishers and editors of scientific journals. Correspondents include Gustaf Arrhenius, Francis Crick, Gerald F. Joyce, Anastassia Kanavarioti, Stanley L. Miller, Peter E. Nielsen, Alan W. Schwartz, and James D. Watson. Arranged alphabetically by surname or corporate name.

Box 38 Folder 6
A - Miscellaneous
Box 38 Folder 7
Academic Press, Inc., 1964-1999
Box 38 Folder 8
Acevedo, Oscar L., 1984-1989
Box 38 Folder 9
Altman, Sidney, 1985-2006
Box 38 Folder 10
Altstein, Anatoly D., 1989-1995
Box 38 Folder 11
American Chemical Society, 1999-2005
Box 38 Folder 12
Anne, Agnès, 1998
Box 38 Folder 13-15
Arrhenius, Gustaf, 1987-2002
Box 39 Folder 1
Ashkenasy, Gonen, 2004-2005
Box 39 Folder 2
Assa-Munt, Nuria, 1982-1993
Box 39 Folder 3
Astrobiology , 2002-2006
Box 39 Folder 4-5
B - Miscellaneous
Box 39 Folder 6
Baasov, Timor, 1999
Box 39 Folder 7
Bar-Nun, Akiva, 1994-1995
Box 39 Folder 8
Bartel, David P., 1997-2001
Box 39 Folder 9
Beichman, Charles A., 2000-2001
Box 39 Folder 10
Benirschke, Kurt, 1990-2000
Box 39 Folder 11
Benner, Steven A., 1990-1999
Box 39 Folder 12
Benzer, Seymour, 1991-1998
Box 39 Folder 13
Bhargava, Pushpa Mittra, 1987-1991
Box 39 Folder 14
Biebricher, Christof, 1986-2000
Box 39 Folder 15
Biemann, Klaus, 1999-2007
Box 39 Folder 16
Bioconjugate Chemistry , 1994-2003
Box 39 Folder 17
Bioinorganic Chemistry , 1969-1978
Box 39 Folder 18
BioScience Reports , 1988-1989
Box 39 Folder 19
Blocher, Markus, 1997
Box 39 Folder 20
Bor, Yeou-cherng, 1995-2002
Box 39 Folder 21
Bowers, Norman, 1996-1997
Box 39 Folder 22
Brack, André, 1990-2001
Box 39 Folder 23
Bräse, Stefan, 1994-1995
Box 39 Folder 24
Braterman, Paul S., 1993-1994
Box 39 Folder 25
Breaker, Ronald, 1996-2001
Box 39 Folder 26
Bretscher, Mark S., 2004
Box 39 Folder 27
Bullard, Edward (Teddy), 1975
Box 39 Folder 28
Burckhalter, Joseph H., 1997
Box 39 Folder 29
Bushman, Frederic (Rick), 1992-2007
Box 39 Folder 30
C - Miscellaneous
Box 39 Folder 31
Cambridge Philosophical Society, 1996-2006
Box 39 Folder 32
Cambridge University Press, 1993-2003
Box 39 Folder 33
Carney, Diane, 1997-1998
Box 39 Folder 34
Cavalier-Smith, Thomas, 1988
Box 39 Folder 35
Cech, Thomas R., 1982-1996
Box 40 Folder 1
Chalmers, John H., 2003
Box 40 Folder 2
Cheikh, Azzouz Ben, 1987-1989
Box 40 Folder 3
Chemical and Engineering News , 1999-2003
Box 40 Folder 4
Chemical Physics Letters , 1971
Box 40 Folder 5
Chemical Weapons Convention, 1996
Box 40 Folder 6
Chemistry and Biology , 1993-2000
Box 40 Folder 7
Chen, Chi-Hong Betty, 1982
Box 40 Folder 8
Chetverin, Alexander, 1998
Box 40 Folder 9
Christian, Andreas, 1989
Box 40 Folder 10
Claude, Hélène, 1992
Box 40 Folder 11
Cleaves, Jim, 2001
Box 40 Folder 12
Cold Spring Harbor Laboratory, 1994-2007
Box 40 Folder 13
Cook, Mariana, 2003-2005
Box 40 Folder 14
Cornell Evolution Project, 2003
Box 40 Folder 15
Cotton, F. Albert, 2002

Includes photograph.

Box 40 Folder 16-17
Crick, Francis H.C., 1967-2004
Box 40 Folder 18
Current Biology , 1994-2004
Box 40 Folder 19
D - Miscellaneous
Box 40 Folder 20
Darwin Molecular Corporation, 1993-1994
Box 40 Folder 21
Davies, Julian E., 1990-1996
Box 40 Folder 22
Deamer, David W., 1988-2002
Box 40 Folder 23
de Duve, Christian, 1989-2003
Box 40 Folder 24
De Jonghe, Steven, 1999-2000
Box 40 Folder 25
Demetrius, Lloyd, 1987-1988
Box 40 Folder 26
Dickerson, Richard E., 1987-2004
Box 40 Folder 27
Diederichsen, Ulf, 2003
Box 40 Folder 28
Doolittle, Russell F., 1987-1996
Box 41 Folder 1
Dunitz, Jack D., 1995-2003
Box 41 Folder 2
Duvernoy, Henri and Roger Guillemin, 1967-2001
Box 41 Folder 3
Dyson, Freeman J., 1965-1999
Box 41 Folder 4
E - Miscellaneous
Box 41 Folder 5
Eaton, William A., 1996

Includes group photograph.

Box 41 Folder 6
Eckstein, Fritz, 1990-1993
Box 41 Folder 7
Eigen, Manfred and Ruthild Winkler-Oswatitsch, 1985-1999
Box 41 Folder 8
Encyclopedia of Evolution , 2000
Box 41 Folder 9
Encyclopedia of Life Sciences , 1999
Box 41 Folder 10
Engeln, Henning, 1995
Box 41 Folder 11
Ertem, Gözen, 1990-2000
Box 41 Folder 12
Eschenmoser, Albert, 1987-2007
Box 41 Folder 13
Etaix, Elizabeth, 1993-1998
Box 41 Folder 14
F - Miscellaneous
Box 41 Folder 15
Fakhari, Habib and Farideh Hooshmand, 1977-1980
Box 41 Folder 16
Farrell, Nick, 1992-1993
Box 41 Folder 17
Feigin, Alexander M., 1989
Box 41 Folder 18
Felsenfeld, Gary, 1991-1993
Box 41 Folder 19
Ferreira, Ricardo, 1991-2004
Box 41 Folder 20
Ferris, James P., 1990-2003
Box 41 Folder 21
Flitterman, Yafa, 1996

Includes photograph of Francis Crick.

Box 41 Folder 22
Foster, Ted F., 1990-1991
Box 41 Folder 23
Fox, Sidney W., 1997-1998
Box 41 Folder 24
Fresco, Jacques R., 1988-1998
Box 42 Folder 1
G - Miscellaneous, 1996
Box 42 Folder 2
Gajdusek, D. Carleton, 1989
Box 42 Folder 3
Gailimov, Erik M., 2002-2005
Box 42 Folder 4
Gallant, John, 1993
Box 42 Folder 5
Gao, Kui, 1997-2003
Box 42 Folder 6
Gene Emergence Project, 1998-1999
Box 42 Folder 7
Ghadiri, M. Reza, 1990-2005
Box 42 Folder 8
Gillon, Jim, 2001
Box 42 Folder 9
Gingeras, Thomas, 1989
Box 42 Folder 10
Glanz, Delbert E., 1990-1999
Box 42 Folder 11
Gong, Jeh-Tween, 1996
Box 42 Folder 12
Green, Mark, 1999-2004
Box 42 Folder 13
Grzeskowiak, Kazimierz, 1981-2001
Box 42 Folder 14
Guillemin, Roger, 1970-1977
Box 42 Folder 15
Gut, Ivo, 1997
Box 42 Folder 16
H - Miscellaneous
Box 42 Folder 17
Haertlé, Tomasz, 1981-1998
Box 42 Folder 18
Hamilton, W.D. (Bill), 1995
Box 42 Folder 19
Hammond, Jim, 2006
Box 42 Folder 20
Hampton, Tyler, 2005
Box 42 Folder 21
Harada, Kaoru, 1995-2003
Box 42 Folder 22
Harada, Kazuo, 2000 -2004
Box 42 Folder 23
Harrison, Kervin, 1995
Box 42 Folder 24
Hartman, Hyman, 1992-2005
Box 42 Folder 25
Hazen, Robert, 1999-2007
Box 42 Folder 26
Helmer, Magdalena, 2003-2004
Box 42 Folder 27
Herdewijn, Piet, 1998-2006
Box 42 Folder 28
Holland, John H., 1992
Box 42 Folder 29
Holley, Robert, 1970-1974
Box 42 Folder 30
Holliday, Robin, 1984-2003
Box 42 Folder 31
Horeis, Heinz, 1998
Box 42 Folder 32
Hornblower, Simon, 1995
Box 43 Folder 1
Horowitz, Norman H., 1998-2001
Box 43 Folder 2
Hud, Nicholas V., 1999-2007
Box 43 Folder 3
I - Miscellaneous
Box 43 Folder 4
Inoue, Tan, 1988
Box 43 Folder 5
International Society for Nucleosides, Nucleotides, and Nucleic Acids, 2001
Box 43 Folder 6
Isis Pharmaceuticals, 1989-1994
Box 43 Folder 7
J - Miscellaneous
Box 43 Folder 8
James, Brennig, 1997
Box 43 Folder 9
James, William, 1999
Box 43 Folder 10
Jencks, William P., 1989-1990
Box 43 Folder 11
John Wiley & Sons, Inc., 2006
Box 43 Folder 12
Jordan, Stephan, 1993
Box 43 Folder 13
Journal of Molecular Evolution , 1969-2006
Box 43 Folder 14
Journal of the American Chemical Society , 1995-2006
Box 43 Folder 15
Journal of Theoretical Biology , 1990-2006
Box 43 Folder 16
Joyce, Gerald F. (Jerry), 1982-2005
Box 43 Folder 17
Jukes, Thomas H., 1990-1997
Box 43 Folder 18
Jungck, John R., 1990
Box 43 Folder 19
Jurgenson, Tom, 1999
Box 43 Folder 20
K - Miscellaneous
Box 43 Folder 21-22
Kanavarioti, Anastassia (Tessi), 1985-2005
Box 43 Folder 23
Kasting, Jim, 2000-2002
Box 43 Folder 24
Kaufmann, Stuart A., 1990-1994
Box 43 Folder 25
Kay, Lily E., 1993
Box 43 Folder 26
Ke, Wen, 1998
Box 43 Folder 27
Kent, Stephen B.H., 1996-1999
Box 43 Folder 28
Keynes, Richard D., 1994-1999
Box 43 Folder 29
Khorana, H. Gobind, 1994-2000
Box 43 Folder 30
Kilmartin, Paul, 1997-2002
Box 43 Folder 31
Kirchweger, Gina, 2006
Box 43 Folder 32
Kishore, Uday, 1995
Box 44 Folder 1
Kluwer Academic Publishers, 1996-1998
Box 44 Folder 2
Knowles, Jeremy R., 1988-1992
Box 44 Folder 3
Kolb, Vera, 1994-1997
Box 44 Folder 4
Kolman, Barry, 1999
Box 44 Folder 5
Koppitz, Marcus, 1995-1999
Box 44 Folder 6
Kornberg, Arthur, 1990-1998
Box 44 Folder 7
Kozlov, Igor A., 1996-2006
Box 44 Folder 8
Kramer, Fred Russell, 1985-2001
Box 44 Folder 9
Kushnirov, Vitaly, 1998
Box 44 Folder 10
L - Miscellaneous
Box 44 Folder 11
Lacey, James C., Jr., 1990-1993
Box 44 Folder 12
Lahav, Noam, 1985-1998
Box 44 Folder 13
Lancet, Doron, 1996-2006
Box 44 Folder 14
Lanouette, William, 1993-1998
Box 44 Folder 15
Lawless, James, 1994
Box 44 Folder 16
Lazcano-Araujo Reyes, Antonio, 1996-2007
Box 44 Folder 17
Le Doan, Trung, 1986-2004
Box 44 Folder 18
Leffert, Hyam L., 1995-1998
Box 44 Folder 19
Leonard, Nelson J., 1987-1997

Includes group photograph.

Box 44 Folder 20
Li, Xiao-Ru, 1992
Box 44 Folder 21
Lippard, Stephen J., 1990-1992
Box 44 Folder 22
Litvin, Arkadi, 1996-1997
Box 44 Folder 23
Liu, Rihe, 1993-2007
Box 44 Folder 24
Luisi, Pier Luigi, 1994-1997
Box 44 Folder 25
Lyons, James R., 1998
Box 44 Folder 26
M - Miscellaneous
Box 44 Folder 27
Magni, Guilio, 1995
Box 44 Folder 28
Martin-Polo, Jesus, 1988-1992
Box 44 Folder 29
Maurel, Marie-Christine, 1996-2004
Box 44 Folder 30
Menninger, John, 1999
Box 44 Folder 31
Meselson, Matthew S., 2000
Box 44 Folder 32
Meyer, Michael A., 1998-2001
Box 44 Folder 33
Michalski, Jan Tomasz, 1985-1994
Box 44 Folder 34
Miller, Stanley L., 1990-2007
Box 44 Folder 35
Misra, K.K., 1992-1993
Box 45 Folder 1
Mojzsis, Stephen J., 1996-2001
Box 45 Folder 2
Moonay, David J., 2003
Box 45 Folder 3
Morrison, David, 2001
Box 45 Folder 4
Moses, Vivian, 1994-1995
Box 45 Folder 5
Müller, Ulrich, 2000
Box 45 Folder 6
N - Miscellaneous, 1995
Box 45 Folder 7
Nagyvary, Joseph, 1982-1996
Box 45 Folder 8
Nassal, Michael, 1992
Box 45 Folder 9
National Aeronautics and Space Administration (NASA), 1990
Box 45 Folder 10
National Center for Science Education, 2002
Box 45 Folder 11
National Film Board of Canada, 1998-2001
Box 45 Folder 12
National Institutes of Health, 1988-1989
Box 45 Folder 13
National Research Council, 1999
Box 45 Folder 14
National Science Foundation, 1990-2004
Box 45 Folder 15
Nature , 1990-2003
Box 45 Folder 16
Näveke, Arne, 1995
Box 45 Folder 17
Neves, Frederico, 2006
Box 45 Folder 18
Ng, Kam-Mui Eva, 1984-1990
Box 45 Folder 19
Nicolaou, K.C., 1991-1994
Box 45 Folder 20-21
Nielsen, Peter Eigil, 1994-2000
Box 45 Folder 22
Ninio, Jacques, 1986-1989
Box 45 Folder 23
Noller, Harry F., 1992-1996
Box 45 Folder 24
Nucleic Acids Research , 1990-2006
Box 45 Folder 25
O - Miscellaneous
Box 45 Folder 26
Ohnsorge, Richard, 1994
Box 45 Folder 27
Olson, Clay, 1999-2003
Box 45 Folder 28
Organic Letters , 2001-2003
Box 45 Folder 29
Orgel, Henry, 1993
Box 45 Folder 30
Origins of Life and Evolution of the Biosphere , 1984-2002
Box 45 Folder 31
Oró, Juan, 1989-1996
Box 45 Folder 32
Otroshchenko, Vladimir A., 1985-1989
Box 45 Folder 33
Oxford University Press, 1990-2002
Box 46 Folder 1
P - Miscellaneous
Box 46 Folder 2
Pace, Norman R., 1991
Box 46 Folder 3
Palomino-Angeles, Miguel, 1999
Box 46 Folder 4
Palyi, Gyula, 1999-2000
Box 46 Folder 5
Pascal, Robert, 2005
Box 46 Folder 6
Paul, Dieter, 2004
Box 46 Folder 7
Peck, Joel, 1997
Box 46 Folder 8
Pitsch, Stefan, 1998
Box 46 Folder 9
Platt, John, 1989
Box 46 Folder 10
Pollard, Thomas Dean, 1997-2004
Box 46 Folder 11
Pouyani, Tara, 1992-1993
Box 46 Folder 12
Powell, Paul D., 2001
Box 46 Folder 13
Price, Buford, 2006
Box 46 Folder 14
Proceedings of the National Academy of Sciences , 1990-2007
Box 46 Folder 15
Profiles in Science , 2004-2007
Box 46 Folder 16
Project Dragonfly, 1994-1996
Box 46 Folder 17
Pross, Addy, 2002
Box 46 Folder 18
Prusiner, Stanley B., 1992
Box 46 Folder 19
Pyne, Solana, 2003
Box 46 Folder 20
Q - Miscellaneous
Box 46 Folder 21
The Quarterly Review of Biology , 1999-2003
Box 46 Folder 22
R - Miscellaneous
Box 46 Folder 23
Race, Margaret, 1997-1998
Box 46 Folder 24
Rauchfuss, Horst, 2003
Box 46 Folder 25
Rebek, Julius, Jr. and Mitra Tayadoni-Rebek, 1990-2002
Box 46 Folder 26-29
Reprint requests, 2004-2006
Box 46 Folder 30
Rich, Alexander, 1992-2006
Box 46 Folder 31
Rivier, Jean, 1998
Box 46 Folder 32
Robins, Roland K., 1988
Box 46 Folder 33
Rodriquez, Libaniel, 1989
Box 47 Folder 1
Rosemeyer, Helmut, 1993
Box 47 Folder 2
Ross, David, 2005
Box 47 Folder 3-4
S - Miscellaneous
Box 47 Folder 5
Sacks, Oliver, 2005
Box 47 Folder 6
Sagan, Carl, 1990-1994
Box 47 Folder 7
Salk family, 1999-2000
Box 47 Folder 8
Sanchez, Robert A., 1998-1999
Box 47 Folder 9
Sawai, Hiroaki, 1992-1998
Box 47 Folder 10
Schmidt, Jürgen, 1995-1999
Box 47 Folder 11
Schopf, J. William (Bill), 1993-2001
Box 47 Folder 12
Schroeder, Julian, 2001
Box 47 Folder 13
Schubert, David, 1998
Box 47 Folder 14-15
Schwartz, Alan W., 1983-2005

Includes group photograph with Orgel.

Box 47 Folder 16
Schwienhorst, Andreas, 1988
Box 47 Folder 17
Science , 1997-2001
Box 47 Folder 18
The Sciences , 1990-1995
Box 47 Folder 19
Seckbach, Joseph, 2002-2003
Box 47 Folder 20
Seebach, Dieter, 1997-2002
Box 47 Folder 21
Seela, Frank, 1991-1996
Box 47 Folder 22
Seidman, Michael, 2002-2003
Box 47 Folder 23
Senter, Peter, 1995
Box 47 Folder 24
Shabarova, Zoe Alekseevna, 1987-1997
Box 48 Folder 1
Shapiro, Robert, 1997-2001
Box 48 Folder 2
Shepard, Mike, 1999-2000
Box 48 Folder 3
Shimizu, Mikio, 1995-2004
Box 48 Folder 4
Shinozaki, Tetsuya, 1990
Box 48 Folder 5
Shulman, Robert G., 1994
Box 48 Folder 6
Sobell, Henry Martinique (Hank), 2003
Box 48 Folder 7
Sommers, Fred, 1996-2002
Box 48 Folder 8
Springsteen, Greg, 2005
Box 48 Folder 9
Stackhouse, Joseph, 1996-1998
Box 48 Folder 10
Staves, Mark, 1990
Box 48 Folder 11
Steitz, Thomas A., 1987-1998
Box 48 Folder 12
Stribling, Roscoe, 1986-1991
Box 48 Folder 13
Strick, James, 2001-2003
Box 48 Folder 14
Sulston, John, 1986-2002
Box 48 Folder 15
Sutherland, John D., 2002
Box 48 Folder 16
Sutherland, Stuart, 1990-1995
Box 48 Folder 17
Syntex Corporation, 1986
Box 48 Folder 18
Szostak, Jack W., 1989-2006
Box 48 Folder 19
T - Miscellaneous
Box 48 Folder 20
The Teaching Company, 2004-2005
Box 48 Folder 21
Tessis, Ana Claudia, 1991-1992
Box 48 Folder 22
Thomas, John Meurig, 1995-2002
Box 48 Folder 23
Tohidi, Mary, 1985-1991
Box 48 Folder 24
Trends in Biotechnology , 1989-2001
Box 48 Folder 25
Trent, Jonathan, 1993-2000
Box 48 Folder 26
Trowbridge, Ian, 1995
Box 48 Folder 27
Tschirgi, Robert, 1996-1999
Box 48 Folder 28
Turnbull, Ken, 1998
Box 48 Folder 29
Turner, B.M., 1993-1994
Box 48 Folder 30
U - Miscellaneous
Box 48 Folder 31
Uhlenbeck, Olke, 1990-1991
Box 48 Folder 32
University of Cambridge, 1990-2006
Box 48 Folder 33
University of Iowa, 2002
Box 48 Folder 34
Usher, David A., 1977-1994
Box 48 Folder 35
U.S. Senate and House of Representatives, 1991-1993

Correspondence to and from U.S. Congress members regarding NASA and NIH funding.

Box 48 Folder 36
V - Miscellaneous
Box 48 Folder 37
Verma, Inder, 1997-2000
Box 48 Folder 38
Visser, Geb M., 1983-1993
Box 48 Folder 39
Von Hoff, Daniel D., 1988-1989
Box 48 Folder 40
von Kiedrowski, Gunter, 1983-1999
Box 48 Folder 41
Vorbruggen, Helmut, 1990-2002
Box 49 Folder 1
W - Miscellaneous
Box 49 Folder 2
Wächtershäuser, Günter, 2000
Box 49 Folder 3
Wahl, Geoffrey M., 1993-1998
Box 49 Folder 4
Watson, James D., 1990-2007
Box 49 Folder 5
Webb, Thomas R., 1980-1992
Box 49 Folder 6
Weber, Arthur L., 1990-1998
Box 49 Folder 7
Weber, Jeff, 2003-2005
Box 49 Folder 8
Weiner, Alan M., 1987-1990
Box 49 Folder 9
The Welch Foundation, 1997-2005
Box 49 Folder 10
Wengel, Jesper T., 1999
Box 49 Folder 11
Westheimer, Frank H., 1988-1992
Box 49 Folder 12
Whidden, Ivan, 2000
Box 49 Folder 13
Whiffen, David H., 1993

Includes biographical information about chemist Leslie Sutton.

Box 49 Folder 14
Winter, Holger, 1994
Box 49 Folder 15
Witowski, Jan, 1995-2003
Box 49 Folder 16
Wu, Taifeng, 1989-2002
Box 49 Folder 17
X - Miscellaneous
Box 49 Folder 18
Y - Miscellaneous
Box 49 Folder 19
Yanagawa, Hiroshi, 1993-1998
Box 49 Folder 20
Yockey, Hubert, 2000-2005
Box 49 Folder 21
Z - Miscellaneous
Box 49 Folder 22
Zelibor, Joe, 1998
Box 49 Folder 23
Zhang, Shuguang, 2001-2003
Box 49 Folder 24
Zhao, Yu-Fen, 1996-2006
Box 49 Folder 25
Zhou, Mu-Ying, 1998-1999
Box 49 Folder 26
Zhu, Zhengrong, 1995
Box 49 Folder 27
Zhu, Zhongyu, 1999-2000
Box 49 Folder 28
Zieboll, Gerhard, 1990-1997
Box 49 Folder 29
Zielinski, Wojciech S., 1982-1988
Box 49 Folder 30
Zubay, Geoffrey, 1996-2002
Box 49 Folder 31
Zuckerkandl, Emile, 1990
Box 49 Folder 32
Zydowsky, Tom, 1999

TALKS AND LECTURES

Scope and Content of Series

Series 10) TALKS AND LECTURES: Invitations, correspondence, abstracts, figures, drafts, and ephemera for Orgel's talks on molecular biology and the origins of life (most of the folders do not contain full drafts of Orgel's prepared comments). The first items in the series are transcripts of biochemistry lectures broadcast on European radio in the 1950s. Arranged chronologically.

Box 49 Folder 33
Frontiers of Knowledge: "Biological Catalysts" and "Principles of Catalysis", 1959 March 24-31

Radio broadcast transcripts for the European English Service.

Box 49 Folder 34
Molecular Replication. International Astronomical Union (IAU) Symposium 112: The Search for Extraterrestrial Life - Recent Developments, Boston, 1984 June 19
Box 49 Folder 35
Chemical Models for Replication. Gordon Research Conference on the Origin of Life, Colby-Sawyer College, New London, NH, 1984 August 23
Box 49 Folder 36
Non-Enzymatic Template-Directed Synthesis. Fourth Conversation in Biomolecular Stereodynamics, Albany, New York, 1985 June 4-8
Box 49 Folder 37
Replication Assisted Assay. Army Research Office Fourth Biodetection workshop, Cashiers, NC, 1986 April 16
Box 49 Folder 38
Origin of Life. India, 1988 December 14
Box 49 Folder 39
Signs of Life. To Boldly Go: America's Next Era in Space. NASA, 1995 January 23
Box 50 Folder 1
Template Catalysis and the Origins of Life. The Year of Louis Pasteur international symposium, Rio de Janeiro, 1995 February 20
Box 50 Folder 2
The RNA World. American Chemical Society Pauling Award symposium, Eugene, OR, 1995 October 28
Box 50 Folder 3
Formation of Polyamides on RNA Templates, Minerals, and Micelles. Gordon Research Conference: Origin of Life, Ventura, 1996 January 7-12
Box 50 Folder 4
The RNA World and the Origins of Life. William C. Ferguson memorial lecture, Washington University, St. Louis, 1996 March 13
Box 50 Folder 5
Overview on RNA and RNA Analogue Replication. International Society for the Study of the Origin of Life (ISSOL) '96, Orléans, France, 1996 July 7-12
Box 50 Folder 6
Molecular Replication. Forum on the Origins of Life, Gothenburg, Sweden. Template-Directed Synthesis and the Origins of Life. Danish Biological Society, Copenhagen, 1997 April 7-11
Box 50 Folder 7
Information Transfer Between Nucleic Acids and Peptide Nucleic Acids (PNA). With Jürgen G. Schmidt, et al. American Chemical Society 33rd western regional meeting, Irvine, CA, 1997 October 23
Box 50 Folder 8
The NASA Specialized Center of Research and Training (NSCORT) in Exobiology. With Jeffrey L. Bada, et al. NASA Ames Research Center, 1997 November 18
Box 50 Folder 9
Template-Directed Synthesis of DNA-PNA Chimeras. With Marcus Koppitz. NASA Ames Research Center, 1997 November 19
Box 50 Folder 10
Life on the Rocks - Minerals and the Origin of Life. Gordon Research Conference, Ventura, 1999 February 25
Box 50 Folder 11
The Origin of Information-Containing Living Cells. Gold Medal Symposium on the Origin of Life. UC Los Angeles, 2000 April 7
Box 50 Folder 12
How Did Life Begin on the Earth? American Chemical Society, San Diego Section, 2000 May 16

Orgel was presented the 2000 San Diego Section Outstanding Scientist Award by the American Chemical Society.

Box 50 Folder 13
NSCORT and NAI. National Academies' Committee on the Origins and Evolution of Life. SETI Institute, Mountain View, CA, 2001 November 1
Box 50 Folder 14
GNA. UC Irvine, 2005
Box 50 Folder 15
A Review of Recent Ideas About the Origin of Life. Osher Institute, 2006-2007
Box 50 Folder 16
Origin of Life talks, undated
Box 50 Folder 17
Sequestration. Beijing, undated

WRITINGS

Scope and Content of Series

Series 11) WRITINGS: Drafts, correspondence, notes, illustrations, abstracts, data, outlines, reviews, and publishing agreements regarding Orgel's published and unpublished writings. Arranged in three subseries: A) Articles, B) Books, and C) Notes.

A) Articles: Drafts, correspondence, figures, abstracts, reviews, data, and publishing agreements for Orgel's articles on molecular biology, nucleic acids, replication, origins of life, peptides, and polymerization. A small amount of writings are in French. Arranged alphabetically by title.

B) Books: Drafts, correspondence, illustrations, outlines, notes, reviews, and publishing agreements for Orgel's books on chemistry and molecular biology. Titles include An Introduction to Transition Metal Chemistry: Ligand Field Theory (1960); The Origins of Life: Molecules and Natural Selection (1973); The Origins of Life on the Earth (with Stanley L. Miller, 1974); and a chemistry thesis submitted to Oxford University. Includes partial drafts and illustrations for an unpublished 2007 manuscript on the origins of life. Arranged alphabetically by title.

C) Notes: Orgel's scientific and bibliographic notes on chemistry and molecular biology. Arranged alphabetically by title.

Articles

Box 50 Folder 18
Adaptation to Wide-Spread Disturbance of Enzyme Function, 1964
Box 50 Folder 19
Adenine, 1998-1999
Box 50 Folder 20
Adsorption and Polymerization of Oligonucleotides on Organic Solid Surface. With Kui Gao
Box 50 Folder 21
Albery and Knowles Made Easy, 1985-1986
Box 51 Folder 1
Alternative Genetic Systems
Box 51 Folder 2
Alternatives to Nucleic Acids as Informational Macromolecules. With Stanley L. Miller, 1989
Box 51 Folder 3
An Antidote to PNAS or Cell , 1995
Box 51 Folder 4
Appendix C: Additional Perspectives on Contamination from Space. In Evaluating the Biological Potential in Samples Returned from Planetary Satellites and Small Solar System Bodies (National Academy Press, 1998), 1997
Box 51 Folder 5
Are You Serious Dr. Mitchell?, 1999
Box 51 Folder 6
Base Composition, 1987
Box 51 Folder 7
Blunt-End and Single-Strand Ligase Activities of E. coli Ligase and How These Activities Militate Against an In Vitro, Ligase-Based, Amplification Scheme. With Kevin J. Barringer, et al, 1989
Box 51 Folder 8
Carbonyl Sulfide-Mediated Prebiotic Formation of Peptides. With Luke Leman and M. Reza Ghadiri, 2004
Box 51 Folder 9
Carbonyl Sulfide-Mediated Synthesis of Phosphate Anhydrides and Amino Acid Derivatives in Water. With Luke J. Leman and M. Reza Ghadiri, 2005-2006
Box 51 Folder 10
The Catalysis of Nucleic Acid Replication by Surfaces
Box 51 Folder 11
Catalysis of the Oligomerization of O-Phospho-Serine, Aspartic Acid, or Glutamic Acid by Cationic Micelles. With Christof Böhler and Aubrey R. Hill, Jr., 1994-1995
Box 51 Folder 12
Codes Without Commas. With F.H.C. Crick and J.S. Griffith
Box 51 Folder 13
A Comparison of RNA with DNA in Template-Directed Synthesis. With Magdalene Zielinski and Igor A. Kozlov, 1999-2000
Box 51 Folder 14
A Convenient Synthesis of a Novel Nucleoside Analogue. With Kui Gao, 1999-2000
Box 51 Folder 15
CO Stretching Frequencies of Substituted Metal Carbonyls, 1962
Box 51 Folder 16
Double Layer Hydroxide Minerals as Host Structures for Bioorganic Molecules. With Ton Lee, et al
Box 51 Folder 17
Efficient Oligomerization of Negatively-Charged Amino Acids at -20 degrees C. With Rihe Liu, 1997
Box 51 Folder 18
Efficient Transfer of Information from Hexitol Nucleic Acids to RNA During Nonenzymatic Oligomerization. With Igor A. Kozlov, et al, 1999
Box 51 Folder 19
The Electronic Spectra of Sandwich Molecules. With D.A. Levy, 1964-1966
Box 51 Folder 20
Electron Transport Through Conjugated Systems
Box 51 Folder 21
Enantiomeric Cross-Inhibition Revisited. With Jürgen G. Schmidt and Peter E. Nielsen, 1996
Box 51 Folder 22
Enantiomeric Selection in the Reaction of Proline with an Oligonucleotide Terminated by a 3'-Amino-3'-Deoxy A Residue. With Gerhard Zieboll, 1993-1994
Box 51 Folder 23
Encapsulation, 2002
Box 52 Folder 1
Enzymatic Synthesis of Polymers Containing Nicotinamide Mononucleotide. With Rihe Liu, 1995
Box 52 Folder 2
Foreword. In Origins: Genesis, Evolution and the Biodiversity of Life (Joseph Seckbach, editor, 2003), 2003
Box 52 Folder 3-4
Formation of Oligonucleotide-PNA-Chimeras by Template-Directed Ligation. With Marcus Koppitz and Peter E. Nielsen, 1997-1998
Box 52 Folder 5
Genetic Consequences of a Degenerate Code, ca. 1953
Box 52 Folder 6
Geothermal Synthesis and Metabolism, 2006
Box 52 Folder 7
Haematic Enzymes, 1961
Box 52 Folder 8
Heterogeneous Catalysis of Phosphorylation with Trimetaphosphate. With S. Hui and G. Arrhenius, 1993
Box 52 Folder 9
A Highly Enantio-Selective Hexitol Nucleic Acid Template for Nonenzymatic Oligoguanylate Synthesis. With Igor A. Kozlov, et al, 1998-1999
Box 52 Folder 10
Hydrolysis of tRNAPhe on Suspensions of Amino Acids. With Kui Gao, 2000-2001
Box 52 Folder 11
Information Transfer from DNA to PNA by Template-Directed Synthesis. With Jürgen G. Schmidt, et al, 1997
Box 52 Folder 12
Information Transfer from PNA to RNA by Template-Directed Synthesis. With Jürgen G. Schmidt and Peter E. Nielsen, 1997
Box 53 Folder 1
Inhibition of Oligo(glutamine) Precipitation by Glutamine-Containing Peptides. With B.C.F. Chu, 2001
Box 53 Folder 2
Inhibition of Transcription by Dumbbell DNA Containing the Sp1 or E2F Recognition Sequence. With Barbara C.F. Chu, 1995
Box 53 Folder 3
Intracellular Reagents
Box 53 Folder 4
In vitro Integration of Human Immunodeficiency Virus Type 1 cDNA into Targets Containing Protein-Induced Bends. With Yeou-Cherng Bor and Frederic D. Bushman, 1995
Box 53 Folder 5
Is a Double Helix Really Necessary?
Box 53 Folder 6
Letter to the editors of Science. With Gustaf Arrhenius, et al, 1999 January 20
Box 53 Folder 7
Life, Origin of. Encyclopedia of Philosophy , 2004-2005
Box 53 Folder 8
Life - The Origins Of. An Addendum for the M.R.C. (In Triplicate)
Box 53 Folder 9
L'origine de la vie - faits et spéculations. French translation of "The Origin of Life: A Review of Facts and Speculations," Trends in Biochemical Sciences 23, 1998 for Biofutur , 2002
Box 53 Folder 10
A Method for the 32P Labeling of Peptides or Peptide Nucleic Acid Oligomers. With Igor A. Kozlov and Peter E. Nielsen, 1998
Box 53 Folder 11
Minimalist Genetic Systems, 1992
Box 53 Folder 12-13
Molecular Evolution of Peptide Methionine Sulfoxide Reductases (MsrA and MsrB): On the Early Development of a Mechanism That Protects Against Oxidative Damage. With L. Delaye, et al, 2005-2006
Box 53 Folder 14
Molecular Replication: A Review, 1992-1994
Oversize FB-208 Folder 4
Molecular Replication: A Review - Drafts and proofs, 1994
Box 53 Folder 15
The Need for a Combinatorial Approach to Mineral Catalysis, 2002
Box 53 Folder 16
Nonenzymatic Oligomerization Reactions on Templates Containing Inosinic Acid or Diaminopurine Nucleotide Residues. With Igor A. Kozlov, 1999
Box 53 Folder 17
Non-enzymatic Synthesis of RNA and DNA Oligomers on Hexitol Nucleic Acid Templates: The Importance of the A Structure. With Igor A. Kozlov, et al, 1998-1999
Box 54 Folder 1
Nonenzymatic Template-Directed Reactions on Altritol Oligomers, Pre-organized Analogues of Oligonucleotides. With Igor A. Kozlov, et al, 1999
Box 54 Folder 2
Nonenzymatic Template-Directed Synthesis of RNA from Monomers. With I.A. Kozlov, 2000
Box 54 Folder 3
Non-enzymatic Template-Directed Synthesis on RNA Random Copolymers. With G.F. Joyce
Box 54 Folder 4
Nucleic Acid Duplexes Incorporating a Dissociable Covalent Base Pair. With K. Gao, 1999
Box 54 Folder 5
Oligomerization of α-Thioglutamic Acid. With Marie-Christine Maurel, 1999-2000
Box 54 Folder 6
Oligomerization of 3'-Amino-3'-Deoxynucleotides in Aqueous Solution. With W.S. Zielinski and C.B. Chen
Box 54 Folder 7
Oligomerization of Activated D- and L-Guanosine Mononucleotides on Templates Containing D- and L-Deoxycytidylate Residues. With Igor A. Kozlov and Stefan Pitsch, 1998
Box 54 Folder 8
Oligomerization of Deoxyguanosine 5'-Phosphoro-2-Methylimidazolide on a Polycytidylate Template. With Igor A. Kozlov, 1999
Box 54 Folder 9
Oligomerization of L-Gamma-Carboxyglutamic Acid. With Aubrey R. Hill, Jr., 1998
Box 54 Folder 10
Oligomerization of Negatively-Charged Amino Acids by Carbonyldiimidazole. With Aubrey R. Hill, Jr., 1996
Box 54 Folder 11
Oligonucleotides as Probes for Studying Polymerization Reactions in Dilute Aqueous Solution. With Vera Kolb
Box 54 Folder 12
The Origin of Biological Information, 2000-2001
Box 54 Folder 13
The Origin of Life - A Review of Facts and Speculations, 1998-1999

Includes caricature of Sherlock Holmes inspecting a double helix with a magnifying glass, by artist Jamie Simon.

Box 54 Folder 14
The Origin of Life - How Long Did it Take?, 1997-1998
Box 54 Folder 15
The Origin of Life on the Earth, 1993-1994

Article published in Scientific American, October 1994.

Box 55 Folder 1-2
The Origin of Life on the Earth, 1993-1994

Article published in Scientific American, October 1994.

Box 55 Folder 3
The Origins of Life - A Status Report, 1995-1996
Box 55 Folder 4-5
Oxidative Acylation Using Thioacids. With Rihe Liu, 1997
Box 55 Folder 6
PCR with Detachable Primers. With Michael H. Silveira, 1995
Box 55 Folder 7
Peptide Cycles, 1999
Box 55 Folder 8
Peptide Formation on Cysteine-Containing Peptide Scaffolds. With Barbara C.F. Chu, 1999
Box 55 Folder 9
Phosphoramidate Analogs with CG and GC Alternating Sequences. With W.S. Zielinski
Box 55 Folder 10
Phosphorylation of Glyceric Acid in Aqueous Solution Using Trimetaphosphate. With Vera Kolb, 1995
Box 55 Folder 11
Photochemical Synthesis of Condensed Phosphates. With A. Bech
Box 55 Folder 12
Photo- Steady-State and Pyrimidine Photochemistry
Box 55 Folder 13
Polymerization of Amino Acids in Aqueous Solution. With Rihe Liu, 1997
Box 55 Folder 14
Polymerization on the Rocks: Amino Acids and Arginine. With Rihe Liu, 1997
Box 55 Folder 15
Polymerization on the Rocks: Negatively-Charged Amino Acids. With Aubrey R. Hill, Jr. and Christof Böhler, 1996-1997
Box 55 Folder 16
Polymerization on the Rocks: Theoretical Introduction, 1997
Box 56 Folder 1
Polyphosphorylation and Non-Enzymatic Template-Directed Ligation of Oligonucleotides. With Kui Gao, 1999
Box 56 Folder 2
The Possible Role of Mirror-Image Nucleotides in Molecular Evolution. With G.M. Visser, et al
Box 56 Folder 3-4
Prebiotic Adenine Revisited: Eutectics and Photochemistry, 2002-2003
Box 56 Folder 5
Prebiotic Chemistry and the Origin of the RNA World, 2004
Box 56 Folder 6
Prebiotic Cytosine Synthesis. With James P. Ferris, et al, 1995
Box 56 Folder 7
Prebiotic Formation of Phosphate Anhydrides Mediated by Carbonyl Sulfide. With Luke J. Leman and M. Reza Ghadiri, 2005
Box 56 Folder 8
Presentation of Ligands on Hydroxylapatite. With Barbara C.F. Chu, 1996-1997
Box 56 Folder 9
Preventive Mitochondrial Replacement, 1997
Box 56 Folder 10
Prion Replication and Secondary Nucleation, 1996
Box 56 Folder 11
Prior Results from the CBC Phase I
Box 56 Folder 12
Progress Toward Understanding the Origin of the RNA World. With Gerald F. Joyce. In The RNA World, 3rd edition (Raymond Gesteland, editor, 2004), 2004
Box 56 Folder 13
Prospects for Understanding the Origin of the RNA World. With Gerald F. Joyce. In The RNA World, 2nd edition (Raymond Gesteland, editor, 1997), 1997
Box 56 Folder 14
Protein Disulfide Oxidoreductases and the Evolution of the Thermophily: Was the Last Common Ancestor a Heat-Loving Microbe? With Arturo Becerra, et al, 2006-2007
Box 57 Folder 1
Proteins
Box 57 Folder 2
Remote Enantio Selection Transmitted by an Achiral PNA Backbone. With Igor A. Kozlov and Peter E. Nielsen, 1999-2000
Box 57 Folder 3
Retrospective: Francis Crick, 1916-2004, 2004
Box 57 Folder 4
Review of Francis Crick: Discoverer of the Genetic Code (Matt Ridley, 2006), 2006
Box 57 Folder 5
Review of Genesis: The Scientific Quest for Life's Origin (Robert M. Hazen, 2005), 2005-2006
Box 57 Folder 6
"RNA Analogues" and "Combinational Approach to Mineral Catalysis"
Box 57 Folder 7
Sandwich Molecules
Box 57 Folder 8-10
Self-Organizing Biochemical Cycles (Metabolic Cycles for Pedestrians), 1997-2000
Box 57 Folder 11
A Sensitive Method for Detecting Very Small Numbers of Biopolymers (For Example, Nucleic Acids or Cell-Surface Receptors), 1984
Box 57 Folder 12
Separation of "Uncharged" Oligodeoxynucleotide Analogues by Anion Exchange Chromatography at High pH. With Jürgen G. Schmidt and Peter E. Nielsen, 1995
Box 57 Folder 13
Sequence Dependent N-Terminal Degradation of Peptide Nucleic Acid (PNA) in Aqueous Solution. With Magdalena Eriksson, et al, 1998
Box 57 Folder 14
A Simple Procedure for Constructing 5'-Amino-Terminated Oligodeoxynucleotides in Aqueous Solution. With Richard K. Bruick, et al, 1997
Box 57 Folder 15
A Simpler Nucleic Acid, 2000
Box 57 Folder 16
Some 5'-Azido and 5'-Amino-2'-Deoxyribonucleosides, Their 3'-Phospates, and Their 3'-Phosphoimidazolides. With Don E. Gibbs, 1976
Box 57 Folder 17
Some Consequences of the RNA World Hypothesis, 2002-2003
Box 58 Folder 1
The Sorcerer's Apprentice Model, 1985-1986
Box 58 Folder 2
The Specificity of Peptide Chain Extension by N-Carboxyanhydrides. With Ke Wen, 2000
Box 58 Folder 3
The Synthesis of 2'-Deoxy-L-Cytidine-3'-Phosphate. With Igor A. Kozlov, 1998
Box 58 Folder 4
Synthesis of Adenine from HCN Tetramer and Ammonium Formate. With Aubrey Hill, 2001-2002
Box 58 Folder 5
The Synthesis of Peptides Containing Guanidino Groups. With Ke Wen, et al, 2000-2001
Box 58 Folder 6
Synthesis of Long Prebiotic Oligomers on Mineral Surfaces. With James P. Ferris, et al, 1996
Box 58 Folder 7
Target-Sequence Preferences of HIV-1 Integration Complexes in Vitro. With Yeou-cherng Bor, et al, 1995-1996
Box 58 Folder 8
Template Switching Between PNA and RNA Oligonucleotides. With Christof Böhler and Peter E. Nielson, 1995
Box 58 Folder 9
Thiol-Mediated Degradation of DNA Adsorbed on a Colloidal Gold Surface. With Shalu Mittal and Frederic Bushman, 2002-2003
Box 58 Folder 10
Trimetaphosphate-Induced Addition of Aspartic Acid to Oligo(glutamic Acid)s. With Aubrey Hill, 2001-2002
Box 58 Folder 11
Was RNA the First Genetic Polymer?
Box 58 Folder 12
Young Brenner. Cambridge and the Code, 2002

Articles written with Francis Crick for Sydney Brenner's 75th birthday tribute.

Box 58 Folder 13-14
Untitled manuscripts and notes

Books

Box 58 Folder 15
An Introduction to Transition Metal Chemistry: Ligand Field Theory (1960), 1959-1966
Box 59 Folder 1-2
An Introduction to Transition Metal Chemistry: Ligand Field Theory (1960), 1959-1966
Box 59 Folder 3
The Origins of Life: Molecules and Natural Selection (1973). Chapters I and IV
Box 59 Folder 4-10
The Origins of Life on the Earth (with Stanley L. Miller, 1974), 1969-1972
Box 60 Folder 1-3
The Origins of Life on the Earth (with Stanley L. Miller, 1974), 1969-1972
Box 60 Folder 4-5
The Origins of Life , 2007
Box 60 Folder 6
I. A Study of Electron Distributions in Some Heterocyclic Systems. II. A Study of the Polymerisation of Aliphatic Aldimines. Thesis submitted to Magdalen College, School of Chemistry, Oxford University, ca. 1949

Notes

Box 60 Folder 7
Aminocytidine, 1998
Box 60 Folder 8
Biomineralization
Box 60 Folder 9
Chemistry
Box 60 Folder 10
Chemistry notebook, 1976-1989
Box 60 Folder 11
Heterogeneous nucleation, 1996
Box 60 Folder 12
Lecture notes
Box 60 Folder 13
Minerals/crystals
Box 60 Folder 14
Mitochondria
Box 60 Folder 15-16
Notes
Box 60 Folder 17
Proteins
Box 60 Folder 18
Salk experimental data - Mn++
Box 60 Folder 19
Silk fibroin
Box 60 Folder 20
Speculative evolution
Box 60 Folder 21
Summer School in Theoretical Chemistry Problems, 1960
Box 60 Folder 22
Teichoic acid, 1998

PROJECTS AND RESEARCH

Scope and Content of Series

Series 12) PROJECTS: Correspondence, proposals, patents, notes, reports, and data for research projects conducted by Orgel and his laboratory at the Salk Institute. Arranged in seven subseries: A) Patents, B) Dipenidam, C) Laboratory Notebooks, D) Grant Proposals, E) NSCORT in Exobiology, F) Viking Mars Lander, and G) Film Projects.

A) Patents: Patent applications, disclosures, license agreements, correspondence, notes and data for patents based on research by Orgel and his laboratory at the Salk Institute. Topics include DNA sequencing, nucleic acid amplification, human bone tissue, and the chemotherapy medication cytosine arabinoside. Additional patents can be found in the Dipenidam subseries. Arranged alphabetically by patent title.

B) Dipenidam: Patent applications and amendments, correspondence, data, notes, and reports regarding the disinfectant Dipenidam. Orgel was chairman of the scientific board of Chemical Patents Corporation, a company involved in the research and development of Dipenidam for medical, industrial, and agricultural uses. Francis Crick served as consultant for the English subsidiary of the company.

C) Laboratory Notebooks: Laboratory notebooks kept by Orgel and by research associate Robert Sanchez, who was a member of Orgel's lab. Orgel signed many of the entries in Sanchez's notebooks (RS I-XI). Several of these bound notebooks have loose pages with notes and data inserted. Orgel also kept three-ring binders of notes, data and photographs on tRNA and ptRNA studies (H523 - H743). Arranged chronologically.

D) Grant Proposals: Proposals, correspondence, progress reports and notes for research proposals submitted to agencies such as the National Institutes of Health (NIH), the National Science Foundation (NSF), and the National Aeronautics and Space Administration (NASA). Topics include nucleotides and nucleic acids, prebiotic condensation, biochemical evolution, HIV inhibition, and genetic specificity. Arranged alphabetically by proposal title.

E) NSCORT in Exobiology: Correspondence, minutes, reports, grant proposals, publicity materials, logo illustrations and slides regarding the NASA Specialized Center of Research and Training (NSCORT) in Exobiology. The consortium of UC San Diego, The Salk Institute for Biological Studies, and The Scripps Research Institute was founded 1992 to study exobiology and the origins of life and to train researchers in the field. Orgel was one of the principal investigators. Arranged alphabetically by folder title.

F) Viking Mars Lander: Correspondence, notes, data, minutes, and briefings for the NASA Viking Mars Lander project. Orgel was a member of the Molecular Analysis Team for the Lander I and II missions.

G) Film Projects: A film script, transcript, and correspondence for documentaries for which Orgel was interviewed or served as advisor.

Patents

Box 61 Folder 1
Aminomalononitrile and Method of Preparation Thereof. With James P. Ferris, 1965-1967
Box 61 Folder 2
Aminooxazolines and Products Thereof and Processes for Synthesizing Same. With Robert A. Sanchez, 1992-1993
Box 61 Folder 3-5
Cytosine Arabinoside - The Upjohn Company, 1968-1990
Box 61 Folder 6-7
DNA Sequencing. With James W. Patrick, 1984-1990
Box 61 Folder 8
Facilitated Crystallization Through Intermolecular Disulfide-Bond Formation, 1990-1991
Box 61 Folder 9-10
Genset - License agreement, 1994-2000
Box 61 Folder 11
Human Bone Insulin Derived Growth Factors, 1994-1997
Box 62 Folder 1
Hydrolysis of Carbonyl Sulfide. With Reza Ghadiri, 2003
Box 62 Folder 2-3
Ligase-Based Amplification Method, 1988-1990
Box 62 Folder 4
Method for the Direct Conversion of Methane to Aromatic Hydrocarbons. With Robert A. Sanchez, 1966
Box 62 Folder 5
A Method for Using Single-Column Fluorescent Sequencing Technology to Determine Simultaneously Two or More DNA Sequences, 1991-1994
Box 62 Folder 6
Method of Making Nucleic Acid Dimers. With Barbara Chu, et al, 1988
Box 62 Folder 7
Methods and Compositions for Delivery of Therapeutic Agents to Bone Tissue Employing Conjugates of Negatively Charged Peptide Oligomers with Therapeutic Agents. With Barbara C.F. Chu, 1996-1999
Box 62 Folder 8
A Novel Method of Target Amplification Using DNA Ligase, 1987-1988
Box 62 Folder 9-10
Oligodeoxynucleotides and Oligonucleotides Useful as Decoys for Proteins Which Selectively Bind to Defined DNA Sequences. With Barbara Chen Fei Chu, 1990-1994
Box 62 Folder 11
Patent agreements - Salk Institute and UC San Diego, 1964-1974
Box 62 Folder 12
Promoting the Intracellular Degradation of Proteins by the Ubiquitin Pathway, 1994
Box 62 Folder 13
Pyrrolidine Nucleosides, 1988-1989
Box 63 Folder 1-8
Replicative RNA Reporter Systems. With Barbara Chu, et al - GeneTrak Systems, 1986-1996
Box 63 Folder 9
Reporter Amplification - The Sorcerer's Apprentice, 1988
Box 64 Folder 1-3
Target Nucleic Acid Amplification/Detection Systems. With Barbara C.F. Chu and Gerald F. Joyce, 1988-1996
Box 64 Folder 4
Vysis - License agreements, 1994-1996

Dipenidam

Oversize FB-207 Folder 5
Association of Official Agricultural Chemists (AOAC) sporicidal test data, 1970
Box 64 Folder 5
Chemical Patents Corporation - Prospectus and registration statements, 1969-1970
Box 64 Folder 6-8
Correspondence, notes, and data, 1968-1969
Box 65 Folder 1-4
Correspondence, notes, and data, 1969-1971
Oversize FB-207 Folder 5
Dipenidam data, ca. 1972
Box 65 Folder 5-7
Disinfectant Compositions (Dipenidam) - Patent, 1966-1972
Box 65 Folder 8
Intermediate Report on Scientific Progress, 1971

Laboratory Notebooks

Box 66 Folder 1-4
Laboratory notebook RS I - IV, 1965-1967
Box 67 Folder 1-4
Laboratory notebooks RS V - VIII, 1967-1969
Box 68 Folder 1-3
Laboratory notebooks RS IX - XI, 1969-1972
Box 68 Folder 4
Laboratory notebooks H523 - H547, 1999
Box 69 Folder 1-4
Laboratory notebooks H549 - H743, 1999-2001

Grant Proposals

Box 69 Folder 5-7
Aqueous Solution Derivatization of Unprotected RNA/DNA. With Barbara C.F. Chu. National Institutes of Health (NIH), 1983-1997
Box 69 Folder 8
Center on Biocatalysis. With Edward A. Dennis. National Science Foundation (NSF), 1989
Box 70 Folder 1
Chemical Synthesis of Nucleotides. National Institutes of Health (NIH), 1972-1973
Box 70 Folder 2
Design of Novel Types of ds DNA for Reversible and Irreversible (Cross-Linking) Interaction to Transcription Factors. With Zoe Shabarova. Civilian Research and Development Foundation, 1996
Box 70 Folder 3-5
Evolution of Genetic Specificity. With Libaniel Rodriquez and Kazuo Harada. National Institutes of Health (NIH), 1969-1992
Box 70 Folder 6-7
HIV Inhibition by Cross-Linking Antisense RNA via Pt. With Barbara C.F. Chu. National Institutes of Health (NIH), 1989-1996
Box 70 Folder 8-9
Models for the Generation of Prebiotic Condensing Agents. With Alan W. Schwartz. National Aeronautics and Space Administration (NASA), 1982-1989
Box 71 Folder 1-5
Models for the Generation of Prebiotic Condensing Agents. With Alan W. Schwartz. National Aeronautics and Space Administration (NASA), 1989-1999
Box 71 Folder 6
Novel Molecular Probes That Generate Exponentially Amplified Signals. With Fred Russell Kramer, et al. National Science Foundation (NSF), 1986
Box 71 Folder 7-8
Nucleic Acid Analogs: Synthesis and Chemotherapy. National Institutes of Health (NIH), 1971-1976
Box 71 Folder 9
Peptides grant
Box 72 Folder 1
Prebiotic Activation of Amino Acids and Nucleotide Bases. National Science Foundation (NSF), 1972
Box 72 Folder 2-4
Prebiotic Condensation Reactions. With Alan W. Schwartz. National Aeronautics and Space Administration (NASA), 1989-2002
Box 72 Folder 5-6
RNA Polymerase Models - A Consortium Proposal. With James G. Lawless (NASA) and David H. White (University of Santa Clara). National Aeronautics and Space Administration (NASA), 1982
Box 72 Folder 7
Study of Biochemical Evolution. National Science Foundation (NSF), 1970-1972
Box 72 Folder 8
The Use of Insoluble Aggregates in Template Ligation. With M. Reza Ghadiri. National Aeronautics and Space Administration (NASA) exobiology grant, 2001

NSCORT in Exobiology

Box 72 Folder 9-10
Annual reports - Drafts and final report, 1992-1994
Box 73 Folder 1
Annual report, 2000
Box 73 Folder 2
Budget, 1998-2000
Box 73 Folder 3-4
The Chemistry of Early Self-Replicating Systems - Proposal for a NASA Specialized Center of Research and Training in Exobiology. With Stanley L. Miller, et al, 1991-1998
Box 73 Folder 5
Final report, 2002
Box 73 Folder 6-7
Correspondence, minutes, and reports, 1990-1992
Box 74 Folder 1-9
Correspondence, minutes, and reports, 1991-1995
Box 75 Folder 1-6
Correspondence, minutes, and reports, 1995-2003
Box 75 Folder 7
Exobiology grants, 2002
Box 75 Folder 8
Fellowships, 1991-1992
Box 75 Folder 9
Logos - Illustrations and slide, 1992
Box 75 Folder 10
NASA augmentation grant - With Reza Ghadiri, 2005
Box 75 Folder 11-12
Principal investigator meeting minutes, 1993-1995
Box 76 Folder 1-2
Principal investigator meeting minutes, 1995-1999
Box 76 Folder 3
Publicity materials, 1993-1998
Box 76 Folder 4
Review committee meeting, 1998
Box 76 Folder 5-6
Site visits, 1991-2002
Box 76 Folder 7
Visiting review committee meetings, 1993-1994

Viking Mars Lander

Box 76 Folder 8
Briefing for Mars Lander Scientist Solicitation, 1968
Box 76 Folder 9
Correspondence, 1968-1969
Oversize FB-207 Folder 6
Viking Molecular Analysis Team - Logo, undated
Box 76 Folder 10
Viking soil analyses - Correspondence, notes, data, and minutes, 1971
Oversize FB-205 Folder 12
Viking soil analyses - Data, 1971

Film Projects

Box 76 Folder 11
The Search for the Origins of Life, 1993-1994

Film script and correspondence for a proposed television documentary by Geoff Haines-Stiles Productions. Orgel was an advisor for the film.

Box 76 Folder 12
CineNova, 1997

Correspondence regarding interviews of Orgel and other researchers for the television documentary Aliens: Are We Alone by CineNova Productions, Inc.

Box 76 Folder 13
Francis Crick in Conversation with Leslie Orgel and Soraya de Chadarevian. Medical Research Council (MRC) Laboratory of Molecular Biology, 1997 October 14

Transcript and correspondence. The digital video can be found in the Francis Crick Personal Papers, MSS 660.

ORGANIZATIONS AND COMMITTEES

Scope and Content of Series

Series 13) ORGANIZATIONS AND COMMITTEES: Correspondence, reports, minutes, proposals, photographs, and ephemera regarding Orgel's participation in organizations (including the Salk Institute) and committees, particularly on astrobiology and the origin of life. Arranged alphabetically.

Box 77 Folder 1
Complexity and Intelligence group, 2000-2001
Box 77 Folder 2-3
La Jolla Group for Explaining the Origins of Humans (LOH), 1997-2002
Box 77 Folder 4
National Aeronautics and Space Administration (NASA) Astrobiology Institute, 1997-2005
Box 77 Folder 5-6
National Aeronautics and Space Administration (NASA) Astrobiology Oversight Committee, 2000
Box 77 Folder 7-8
National Aeronautics and Space Administration (NASA) Astrobiology Task Force, 2000-2001
Box 77 Folder 9
National Aeronautics and Space Administration (NASA) Mars Sample Handling Oversight and Review Committee, 1996-2002
Box 77 Folder 10
National Research Council (NRC) Space Studies Board - Task Group on Sample Return from Small Solar System Bodies, 1997-1998
Box 78 Folder 1
Nobel Laureate Dinner committee, 1999-2006

Includes photographs of Francis Crick and other Nobel laureates.

Box 78 Folder 2
RNA Tie Club, 1953-2006

Salk Institute

Box 78 Folder 3
Annual scientific report drafts, by Orgel, 1981-2002

Includes Chemical Evolution Laboratory progress reports.

Oversize FB-207 Folder 6
Card signed by Salk Institute employees
Box 78 Folder 4
Chemical Evolution Laboratory summaries, 1980-2003
Box 78 Folder 5
Salk Institute Plan for the Neurosciences - Background briefing paper
Box 78 Folder 6
SETI (Search for Extraterrestrial Intelligence) Institute, 2000-2005

Includes Strategic Planning Group and Center for the Study of Life in the Universe.

PHOTOGRAPHS

Scope and Content of Series

Series 14) PHOTOGRAPHS: Photographs and slides of Leslie Orgel and his colleagues at the Salk Institute of Biological Studies and the UC San Diego Department of Chemistry and Biochemistry. Includes photographs of Francis Crick, James Watson, Robert Sanchez, the Salk Institute, molecular models, and laboratory equipment.

Box 78 Folder 7-8
Leslie Orgel - Portraits and snapshots, ca. 1960-2000
Oversize FB-207 Folder 7
Leslie Orgel - Oversize portraits and snapshots, 1956-ca. 1975

Includes photos of Orgel in laboratory, with Robert Sanchez, and in group photographs.

Box 78 Folder 9
Leslie Orgel and Robert Sanchez, 1967-1970
Box 78 Folder 10
Leslie Orgel, Francis Crick, and James Watson, ca. 1955-1995

Includes RNA Tie Club photo with Alex Rich, 1955.

Box 78 Folder 11-12
Leslie Orgel - Group photographs, ca. 1960-1990
Box 78 Folder 13
Salk Institute - Staff, buildings and laboratories, ca. 1970-1996

Includes Leslie Orgel and Francis Crick.

Oversize FB-207 Folder 8
Salk Institute - Staff and buildings

Includes Leslie Orgel and Francis Crick.

SOUND AND VIDEO RECORDINGS

Scope and Content of Series

Series 15) SOUND AND VIDEO RECORDINGS: One audio recording on reel-to-reel tape of a lecture by Orgel, and one VHS video recording of a lecture by Orgel on the origins of life. Original media is restricted: researchers may request listening or viewing copies in advance of their visit.

Box 79 Folder 1
Frontiers of Science evening meeting - Reel to reel sound recording

Restrictions Apply

Box 79 Folder 2
Template-Directed Polynucleotide Synthesis on Analogs of DNA and RNA - VHS recording, 1999 March 29

Video of a NASA Origins of Life seminar given by Orgel at the Darrin Fresh Water Institute, Rensselaer Polytechnic.

Restrictions Apply