Russell Doolittle Biochemistry Laboratory Records, 1971 - 1998 (MSS 77)

Extent: 87.4 Linear feet (83 records cartons, 8 archives boxes, 16 oversize folders and 1 art bin item)

The records of Dr. Russell F. Doolittle's (1931-2019) biochemistry laboratory at the University of California, San Diego include notebooks related to the first determination of the complete sequence of amino acids in the human fibrinogen molecule, paper files for the amino acid sequences contained in the protein sequence data bank called NEWAT, as well as other research, correspondence and Protein Society files.

Dr. Russell F. Doolittle, professor of chemistry at the University of California, San Diego, headed a campus science laboratory that conducts research in the evolutionary and structural aspects of proteins. In 1979, Doolittle's laboratory successfully analyzed the structure of the amino acid sequence for the human fibrinogen molecule.

During that study, ten to twenty postdoctoral, graduate and undergraduate researchers worked to pull apart and analyze the amino acid sequences in the alpha, beta and gamma chains of fibrinogen. Doolittle adapted a peptide synthesizing machine to break apart peptides and employed an amino acid analyzer to identify the sequences.

The peptide synthesizer, which was the second peptide synthesizer ever constructed, was modeled on the prototype designed by Bruce Merrifield, then of Rockefeller University. Merrifield was later awarded the Nobel Prize for the design of the machine.

The UCSD machine was constructed in 1964 at the instigation of Martin Kamen, a member of the Chemistry faculty. Professor Kamen had seen Merrifield's machine and, on his return to UCSD, asked Arthur Robinson, a graduate student in the Chemistry Department, to oversee construction of the machine. Robinson journeyed back to New York to examine Merrifield's machine more closely and then, after returning to UCSD, began constructing the UCSD machine.

After a period of time, the machine was converted into a peptide sequencer. Instead of building up peptides one amino acid at a time, it would take them apart one amino acid at a time. In 1979, the machine was used to make the first determination of the complete amino acid sequence for the human fibrinogen molecule, which is composed of 2,934 amino acids.

Doolittle also constructed a protein sequence data bank called NEWAT. Sequences identified in the published literature were entered into an electronic database and new sequences were searched against known sequences. In 1983, Doolittle used the data bank to link separate research efforts at the Center for Blood Research in Boston and the National Cancer Institute in Washington, D. C. He related a known cancer gene to a gene with a known function in human cells.

Doolittle participated in the Protein Society as a member and as one of the editorial board that oversaw the society publication, Protein Science.

The Russell Doolittle Biochemistry Laboratory Records document the activities of a UCSD science laboratory engaged in research on the structure of the human fibrinogen molecule.

Accession Processed in 1997

Arranged in three series: 1) NEWAT, 2) LABORATORY NOTEBOOKS and 3) AMINO ACID SEQUENCER.

Accession Processed in 2006

Arranged in eight series: 4) CORRESPONDENCE, 5) LAB NOTEBOOKS, 6) RESEARCH, 7) NEWAT, 8) PROTEIN SOCIETY, 9) PUBLICATIONS, 10) GRANTS/BUDGETS and 11) TEACHING FILES.

This collection has additional unprocessed materials not described in this finding aid. See the UC San Diego Library catalog record to view the acquisition dates and extent of unprocessed additions.

Container List

Accession Processed in 1997

NEWAT

Scope and Content of Series

Series 1) NEWAT: Journal articles, printouts and summary data reports for individual amino acid sequences that were entered into the protein sequence data bank. The series begins with a list that relates the folder title acronym to the name and the journal citation for each amino acid sequence. The materials are arranged alphabetically by acronym.

Box 1 Folder 1
Index to acronyms
Box 1 Folder 2
2GPH to ATHT
Box 2
ATPC1, -2, -3, -4, -5 to CHEY
Box 3
CHEZ to DEGC
Box 4
DGI7 to FBCH1
Box 5
F7BO to GYPD 1 and 2
Box 6
HICT to IF2B
Box 7
IF3E to LYMH
Box 8
M3RD to ORDN
Box 9
OREC to PSPB
Box 10
PSI1 to PYRP
Box 11
SIRV to TFWS
Box 12
TFT4 to VP2S
Box 13
VPIM to ZUKE

LABORATORY NOTEBOOKS

Scope and Content of Series

Series 2) LABORATORY NOTEBOOKS: Notebooks by individual postdoctoral, graduate and undergraduate researchers who worked on the project. Also included are notebooks that contain amino acid analysis charts and high performance liquid chromatography charts. The notebooks are arranged by name of researcher, subproject and type of chart as follows: 2A) Watt, Ken; 2B) Bouma, H.; 2C) Takagi, T.; 2D) Miscellaneous Researchers; 2E) Electric Birefringence; 2F) Peptide Synthesis; 2G) Analysis Charts; and 2H) High Performance Liquid Chromatography Charts.

Watt, Ken

Box 14 Folder 1-2
Book 1 - Beta Chain CNBr / Lysozyme HSer Coupling, 10/1/76 - 9/30/78
Box 14 Folder 3-5
Book 2 - H Beta 0 CN I, 11/1/76 - 8/31/78
Box 14 Folder 6
Book 3 - H Beta 0 CN V, 11/1/76 - 6/30/77
Box 14 Folder 7
Book 4 - H Beta 0 CN VII, 11/1/76 - 7/31/77
Box 14 Folder 8-9
Book 5 - H Beta 0 CN II, 11/1/76 - 9/30/78
Box 14 Folder 10-11
Book 6 - H Beta 0 CN VI, 11/1/76 - 12/31/77
Box 14 Folder 12
Book 7 - Sequence H Beta CN VId, 12/2/76 - 3/31/78
Box 14 Folder 13
Book 8 - H Beta CN II, Glu Cleavage, 1/1/77 - 11/30/77
Box 14 Folder 14
Book 9 - H Beta CN IV, 1/1/77 - 12/31/77
Box 15 Folder 1
Book 10 - H Beta CN III, 1/1/77 - 8/31/77
Box 15 Folder 2-3
Book 11 - Citraconylation, Triptic Digestion of Human 0 Beta Chain, 3/1/77 - 6/1/77
Box 15 Folder 4
Book 12 - H Beta CN Vb, 3/1/77 - 8/31/77
Box 15 Folder 5
Book 13 - CN VI C-2, CN VIf, H Beta CVI VI C-3, CN VI b-1, CN VIC-4, CN VI C-1, CN VIa, 3/1/77 - 5/31/77
Box 15 Folder 6
Book 14 - H Beta CN IVb, 3/1/77 - 7/31/77
Box 15 Folder 7-8
Book 15 - H Beta CN IIIa from Re-chromatog, 05/01/77 - 10/31/77
Box 15 Folder 9
Book 16 - H Beta CN IIIb, CN IVa, 07/01/77 - 08/31/77
Box 15 Folder 10-11
Book 17 - H Beta CN V TR, 07/01/77 - 12/31/77
Box 15 Folder 12
Book 18 - H Beta CN IV TR, Glu, 07/01/77 - 09/31/77
Box 15 Folder 13-14
Book 19 - H Beta CN IVe, 07/01/77 - 10/31/77
Box 15 Folder 15-16
Book 20 - H Beta CN III CT and TR, 07/01/77 - 08/31/77
Box 15 Folder 17
Book 21 - H Alpha 6d Ch, TR, 08/01/77 - 06/30/79
Box 15 Folder 18
Book 22 - H Beta CN V Glu-, 10/01/77 - 01/31/78
Box 16 Folder 1
Book 23 - H Beta CN III TR, 10/1/77 - 10/31/77
Box 16 Folder 2-3
Book 24 - H Beta CT, 11/01/77 - 01/31/78
Box 16 Folder 4
Book 25 - H Beta CN Ne CT, and Sequence, 12/01/77 - 12/31/77
Box 16 Folder 5-7
Book 26 - H Beta Glu, 12/01/77 - 2/28/78
Box 16 Folder 8-9
Book 27 - H Beta CN II Glu EDC Sequence, 01/01/78 - 01/31/78
Box 16 Folder 10-11
Book 28 - Alpha Chain CNI Sequence Summary, H Beta Glu Sequence, 02/01/78 - 05/31/78
Box 16 Folder 12
Book 29 - H Beta CNI GEE DITC Bends, 09/01/78 - 09/31/78
Box 16 Folder 13-14
Book 30 - H Alpha CN1 PL1 SP1 Ch, 10/01/78 - 03/31/79
Box 16 Folder 15-16
Book 31 - H Alpha CNI SPI Ch 2nd, 11/01/78 - 02/28/79
Box 16 Folder 17
Book 32 - PLI SP2 Ch to SGSFRP...E, ENI SP Pool 2, 01/01/79 - 02/28/79
Box 16 Folder 18
Book 33 - H Alpha CN1 SP2 Ch SP2dnp to Ng, 02/01/79 - 03/31/79
Box 16 Folder 19
Book 34 - H Alpha CN1 SP1 Ch, 02/01/79 - 03/31/79
Box 16 Folder 20
Book 35 - H Alpha Chain, 04/01/79 - 06/30/79
Box 17 Folder 1-2
Book 35, cont. - H Alpha Chain, 04/01/79 - 06/30/79
Box 17 Folder 3-4
Book 36 - H Alpha, Glu Digest Continuation of 1/78 Prep (70mg), 05/01/79 - 05/31/79
Box 17 Folder 5-6
Book 37 - H Alpha Glu (sequence) 71mg prep, 05/01/79 - 06/30/79
Box 17 Folder 7-10
Book 38 - H Alpha - Subscript 2 - SP 72 6 mg G50, 06/01/79 - 06/30/79
Box 17 Folder 11
Book 39 - Ch H Alpha CNI PLII, 03/01/78 - 07/31/78
Box 17 Folder 12-14
Book 40 - H Alpha - Subscript 2 - CNI Ch-, 03/01/78 - 03/31/78
Box 17 Folder 15-17
Book 41 - H Alpha CNI Ch Sequence, 04/01/78 - 08/31/78
Box 17 Folder 18
Book 42 - H Alpha, CNI Tryptophan, 04/01/78 - 06/30/78
Box 17 Folder 19-20
Book 43 - H Beta Chain Trypson, 04/01/78 - 05/31/78
Box 17 Folder 21
Book 44 - Frag. D, CN III C, TR, 05/01/78 - 07/31/78
Box 18 Folder 1-3
Book 45 - H Beta (CN Br), HD Beta Tryptic, 05/01/78 - 09/30/78
Box 18 Folder 4
Book 46 - H Alpha CNI PLI Ch, 06/01/78 - 06/30/78
Box 18 Folder 5
Book 47 - H Alpha CNI PLI Ch (EDC), 04/01/78 - 08/31/78
Box 18 Folder 6
Book 48 - H Alpha CNI PL2, Ch2, Ch1, 07/01/78 - 07/31/78
Box 18 Folder 7
Book 49 - II H Alpha CNI Trytophan, 08/01/78 - 03/31/78
Box 18 Folder 8-10
Book 50 - H Alpha CN1 PL1 Ch 2hrs, 37 degrees 1/50 ration, partially GEE, 08/01/78 - 01/31/79

Bouma, H

Box 18 Folder 11-13
Book 1 - I. Human Fibrinogen; Gamma Chain; Citraconyl - Trypsin, G-50; Peaks V, VI, VII, VIII, 9/1/75 - 3/31/76
Box 18 Folder 14-16
Book 2 - Human Fibrinogen; Gamma Chain; Citraconyl - Trypsin, G-50; Peaks II, III, IV, 9/1/75 - 12/31/76
Box 18 Folder 17
Book 3 - Miscellaneous: Anti-human Fibrinogen; 4, 4'-diaminobenzil; TATG synthesis, 9/1/75- 9/30/76
Box 18 Folder 18
Book 4 - Human Fibrinogen; Gamma Chain; Citraconyl - Trypsin, G-50; Peaks II, III, VIII, 1/1/76 - 6/30/76
Box 19 Folder 1-2
Book 4, cont. - Human Fibrinogen; Gamma Chain; Citraconyl - Trypsin, G-50; Peaks II, III, VIII, 1/1/76 - 6/30/76
Box 19 Folder 3
Book 5 - Human Fibrinogen; Gamma Chain; Citraconyl-Trypsin, G-50; Peaks V and VI, 1/1/76 - 8/31/76
Box 19 Folder 4-5
Book 6 - Human Fibrinogen; Gamma Chain; Citraconyl-Tripsin; G-50; Peak II; Deblocked, Trypsin, G-25, 1/1/76 - 3/31/76
Box 19 Folder 6-7
Book 7 - Human Fibrinogen; Gamma Chain; Succinylated, Aminoethylated; Trypsin, G-25; Peaks 1, 4, 5, and 6, 10/1/76 - 1/31/77
Box 19 Folder 8-9
Book 8 - Human Fibrinogen; Gamma Chain; Succinylated, 14 C-aminoethylated; Trypsin, G-25; Peaks 1, 4, 5, and 6 (synthesis: 14 C-bromoethylamine), 12/1/76 - 8/31/77
Box 19 Folder 10-11
Book 9 - Fibrinogen Sulfitolysis; S-sulfo Human Fibrinogen Separations; Gamma Chain Modifications (aminoethylation, cyclohexanedione, tryptic cleavages), 8/1/76 - 11/31/76
Box 19 Folder 12-13
Book 10 - HG, CT2 (HG, CT2, AT3) (HG, CT2, AT4 and AT5); HG CT5; HG CT6; HG CT7, 3/1/77 - 4/30/77
Box 19 Folder 14-15
Book 11 - HG, CT 3B; TRa-2; TRb-2, 4/1/77 - 6/30/77
Box 19 Folder 16-17
Book 12 - Plasmin - 0ib DE-52; CNBr-G-100 Columns; TR-G-25 Columns, 8/1/77 - 1/31/78
Box 19 Folder 18
Book 13 - HF, PLD, CN III B; HF, PLD, CN III C, 12/1/77 - 12/31/77
Box 20 Folder 1
Book 13, cont. - HF, PLD, CN III B; HF, PLD, CN III C, 12/1/77 - 12/31/77
Box 20 Folder 2
Book 14 - HF, PLD, CN II; HF, PLD, CN III, 2/1/78 - 5/31/78
Box 20 Folder 3-4
Book 15 - G - 37 1/2; HF, PLD, CN I, TRA-2; ... A-3; ... A-4, 12/1/77 - 1/31/78
Box 20 Folder 5-8
Book 16 - HF, PLD, CN I, TRA; HF, PLD, CN I, TRB, 12/1/77 - 3/31/78
Box 20 Folder 9-10
Book 17 - Frag D; CN I, TR pH 7.0; Peak B-D, 3/1/78 - 6/30/78
Box 20 Folder 11
Book 18 - Tryptic-digest; Human Fibrinogen; Gamma Chain, 6/1/78 - 7/31/78
Box 20 Folder 12
Book 19 - Fragment D; CN I, TRA; pH 7.0 Trypsin; G-25, 4/1/78 - 7/31/78

Takagi, T

Box 20 Folder 13-14
Book 1 - H Gamma CT Pools I, II, III, DNS; CT I, II, III TATG (electrophoresis, CNBr), 11/1/73 - 7/31/74
Box 20 Folder 15-17
Book 2 - H Gamma CT IV - VIII (gel filtration, paper el., ion exchange - Aminex A5), 11/1/73 - 7/31/74
Box 20 Folder 18
Book 3 - H Gamma CNB R and A; Trypsin I - IV (gel filtration, paper el.), 5/1/74 - 8/31/74
Box 21 Folder 1
Book 3, cont. - H Gamma CNB R and A; Trypsin I - IV (gel filtration, paper el.), 5/1/74 - 8/31/74
Box 21 Folder 2
Book 4 - H Gamma chain; AAA 24, 48,72 hr.; Tryptophan Det with Methane Sulfonic Acid; H Gamma CNI AAA 3/75, 07, 1/73 - 12/31/73
Box 21 Folder 3-4
Book 5 - H Gamma CNI Chymotrypsin Gel Filtration G-25 Paper El, 09/1/74 - 11/30/74
Box 21 Folder 5
Book 6 - H Gamma CNI Pepsin Gel Filtration G-25 Paper El, 10/1/74 - 11/30/74
Box 21 Folder 6-8
Book 7 - H Gamma CNI Pepsin Gel Filtration G-25 Paper El, 10/1/74 - 11/30/74
Box 21 Folder 9
Book 8 - Gamma CN III, IV, V, 9/1/73 - 10/31/74
Box 21 Folder 10-13
Book 9 - 11/73
Box 21 Folder 14
Book 10 - Collagenase Digestion of H0, 3/74 - 4/74
Box 21 Folder 15-18
Book 11 - Plasmin Digestion, 4/74 - 5/74
Box 21 Folder 19
Book 12 - HD, CNBr G-100 Purification, Enzyme Digestions, 1/75 - 3/75
Box 22 Folder 1
Book 12, cont. - HD, CNBr G-100 Purification, Enzyme Digestions, 1/75 - 3/75
Box 22 Folder 2
Book 13 - Separation of D and E on Biogel A 1.5 M, 4 m Guanidine, 2/74 - 7/74
Box 22 Folder 3
Book 14 - HDII: Separation, R and A, Purification, Enzyme Digestion, 8/74 - 12/74
Box 22 Folder 4-5
Book 15 - HE R and A -- G-25, Paper El, 7/74
Box 22 Folder 6-7
Book 16 - Gel Filtration of D and E, HE CNBr -- G-50, Paper El of Peptides, 5/74- 7/74
Box 22 Folder 8-9
Book 17 - HE CNBr (S-S) in E, Purification of CNBr Peptides, 8/74 - 1/75
Box 22 Folder 10-11
Book 18 - FIIB-2, FIIB-3, FIIB-4, FIIB-5, D-D3, 2/74 - 2/75
Box 22 Folder 12-13
Book 19 - CNBr Digestion of H Fibrin, 10/74 - 2/75
Box 22 Folder 14-15
Book 20 - TATG of H Fragments D, E, 2/74
Box 22 Folder 16
Book 21 - H0 CNBR, H Gamma CNBr, 2/74 - 5/74
Box 22 Folder 17
Book 22 - H 14C GEE Labelled Gamma Chain, Fragments from Plasmin Digestion of H GEE Fibrins, 2/74 - 5/74
Box 22 Folder 18
Book 23 - TATG of H Fragment D, E (see envelope), 5/74 - 8/74
Box 22 Folder 19
Book 24 - Human Gamma G-50, Purfication of Pools 4.5 and 6, Enzyme Digestion of Cyanogen Bromide Pools, 12/74 - 02/75
Box 23 Folder 1-2
Book 25 - Beta chain CNBr, G-100 10% HAc Purfication, 08/74 - 12/75
Box 23 Folder 3-4
Book 26 - Separation of H Gamma, Beta Chains CM52, Beta Chain CNBr Peptides AAA, 03/74
Box 23 Folder 5
Book 27 - Bov Gamma CNBr A,B,C, AAA (Bovine)
Box 23 Folder 6
Book 28 - Oxidized Bov Gamma Chain and Its CNBr Fragments, Separation Biogel 1.5 Purification by Paper El, 01/74 - 02/74
Box 23 Folder 7
Book 29 - H Fragment A from Plasmin, digest 10', 90', 15 hrs, Enzyme Digestion, 05/72
Box 23 Folder 8-11
Book A - HF XIII: H "X" Trypsin ( Thermolysin, Chymotrypsin ); PCAase, Pronase, CPase; HX for TATG; P - Ser; Pepsin; Platelet "X", 12/01/72 - 10/31/73
Box 23 Folder 12-13
Book B - Preparation of BF XIII, HF XIII (Biogel A1.5, Platelet F XIII, DE-52 SOS gels); Activation of F XIII; Trypsin Dig. of 14C GEE F XIII; Sulfitolysis of F XIII *; Separation of A and B Chains of F XIII *, 09/01/72 - 09/30/73
Box 23 Folder 14-16
Book C - TATG: H, B FXIII, FXIII *; ClG; Platelet F XIII *; Seattle F XIII *, 11/01/72 - 11/31/73
Box 23 Folder 17-18
Book D - Bov P "X" F XIII; Preparation; Trypsin Digestion; Chymotrypsin; PCA to Th; Trypsin to Th, 10/01/72 - 10/31/73
Box 23 Folder 19
Book E - Bov Gamma ( plasmin, trypsin SDS gels ); GEE B Gamma - Plasmin; B 0 plasmin, 08/01/72 - 03/31/73

Miscellaneous researchers

Box 24 Folder 1-2
Friezner, S. - H Gamma CNI Trypsin, 06/75

Lin, Y

Box 24 Folder 3
H 14C GEE Alpha Electrophoresis; T-boc Reactions T-boc-EA, 02/01/71 - 05/31/71
Box 24 Folder 4-5
Synthesis of HFpA; A-D-S-G-E-G-D-F-A-A-0; Preparation of Bovine Insulin; A and B Chains, 02/01/71 - 05/31/74
Box 24 Folder 6
Maffly, B. and Goldbaum, D. - HPLC, 04/76 - 01/78

Electric Birefringence

Cottrell, B

Box 24 Folder 7-8
Book 1, 1973
Box 24 Folder 9-11
Book 2 - Photographs, computer programs and basic user manual, 1973 - 1974
Box 24 Folder 12-13
Book 3, 1974
Box 24 Folder 14-15
Book 4, 1975
Box 24 Folder 16-17
Book 5, 1975
Box 24 Folder 18
Computer Graphs B/C
Box 25 Folder 1
Computation Book, Oct 22, 1973
Box 25 Folder 2-3
Computer Graphs, Upsilon, Theta
Box 25 Folder 4-5
Data Output. Elbra
Box 25 Folder 6-7
Log Book
Box 25 Folder 8-9
Troll, M. - System logic of the laser birefringence machine, reprints, technical information, equipment specifications

Analysis Charts

Box 27 Folder 4
2 VB Sequence
Box 27 Folder 5
AAA of Gamma Chains Trp Det
Box 27 Folder 6-8
Bead Data SP Digest of PLI
Box 27 Folder 9
Bov Gamma Chains, 1973
Box 27 Folder 10
Bov Gamma Chains II
Box 27 Folder 11
CN I, PL I, SP I, PL II, Tryptic Data, Chymo, SP Peptides, 1979
Box 27 Folder 12
CN - V B, C, and D - B Gamma CN from pH2, SC - pH 9.5, CN5B - pH 9.5, SD - pH 4.5
Box 27 Folder 13
CNBr, Cyanogen Bremide G-75 Runs
Box 27 Folder 14-15
Cys from PL2, SP PLI Parp #6, SP Digest CNI #3, SP Digest CNI #4
Box 27 Folder 16
D1 Binder D1 Non Binder 12/80 R and A Trypsin
Box 28 Folder 1
D2 Alpha - Trypsin
Box 28 Folder 2
D2 Rho Glass Beads
Box 28 Folder 3-4
H Alpha 2, CNI, TFA, CN IB, Trypsin
Box 28 Folder 5-6
H2 CN I PL I Se #2, S rho I TR - G-25
Box 28 Folder 7
H Alpha CNI CNBr = 70% TFA, H0CNI Pl I Glu, Pl 2 Glu
Box 28 Folder 8
H and CNI PL 3
Box 28 Folder 9-10
H Alpha 2, 1977
Box 28 Folder 11
H Alpha CN, 1976
Box 28 Folder 12-14
H Alpha CN III, 1976 - 1978
Box 28 Folder 15-16
H Alpha CN IV, 1975
Box 28 Folder 17
H Alpha CN4A
Box 28 Folder 18
H Alpha CN IV B
Box 29 Folder 1
H Alpha CN31
Box 29 Folder 2
H Alpha CN5B
Box 29 Folder 3
H Gamma Chain CN IV, 1975
Box 29 Folder 4
H Alpha CN CN -VII, 1977 (1 of 2)
Box 29 Folder 5
H Gamma Chain CN V-VII, 1977 (2 of 2)
Box 29 Folder 6
HD R and A BC 1980 D1 Gamma D3 Gamma Trypsin
Box 29 Folder 7-9
H Gamma chain, 1971-1972
Box 29 Folder 10
Gamma Chains Preps CN III, CNIV
Box 29 Folder 11
HXLF CEE 7177 CN I Tal 23
Box 29 Folder 12
Machine H Alpha CN III "G7B", 1976
Box 29 Folder 13
Mellitin Sequence Run, 07/18/80
Box 29 Folder 14
Sequence Guide 1969-70
Box 29 Folder 15
Sequenator log sheet
Box 30 Folder 1-2
SP Digest #4 PLI, TR Digest Over G.50
Box 30 Folder 3
SP Digest CNI #6, SP Digest CNI #9 (8/79), SP Digest CNI #11 (4/79)
Box 30 Folder 4
SP of PLI #3, SP of PLI #5, 11/15/78
Box 30 Folder 5
Trypsin Digest
Box 30 Folder 6-15
Untitled

High Performance Liquid Chromatography Charts

Box 31 Folder 1-3
Untitled
Box 31 Folder 4
Acylase, N-Ac-Ab-C-Sar
Box 31 Folder 5
CMC
Box 31 Folder 6
Electrofocusing
Box 31 Folder 7
Funatsu Peptide
Box 31 Folder 8
HPLC Anion Exchange

Peptide Synthesis

Box 25 Folder 10
- Vol. 2 Number 3, 1985
Box 25 Folder 11
Book 9
Box 25 Folder 12
Book 10

Computation Notebooks

Box 25 Folder 13-18
Notebooks 1-6
Box 26 Folder 1-6
Notebooks 7-12
Box 26 Folder 7
Deoxynucleotide Synthesis, Phosphonylations, Monomer Synthesis, Dimer Synthesis
Box 26 Folder 8
DNA Sequencing 3:728-3D, 1985
Box 26 Folder 9
D.T. Peptide Synthesis
Box 26 Folder 10
Evans, Barbara - Untitled notebook
Box 26 Folder 11
Gel Sequencing
Box 26 Folder 12
Helices
Box 26 Folder 13
Lab Reports

Lamprey Transferrin

Evans, Barbara

Box 26 Folder 14-15
Untitled, 1983
Box 26 Folder 16
DNA Sequencing 463-1B, 1985 - 1986
Box 26 Folder 17
Plasmid Preps, 1984
Box 26 Folder 18
Sequence 1 Molecular Biology, 1984 - 1985
Box 26 Folder 19
Sequencing 2: 613-3B, 463-1B, 1985
Box 26 Folder 20
Nucleotide Synthesis - Ologonucleotide Probes, 1982
Box 26 Folder 21
Peptide Synthesis - James Kobut/R. Doolittle
Box 27 Folder 1-2
Pontes, Manuel
Box 27 Folder 3
RD and MTNICB0

AMINO ACID SEQUENCER

Scope and Content of Series

Series 3) AMINO ACID SEQUENCER: This is the machine adapted by laboratory staff to pull apart amino acids.

Oversize AB-00-01
Sequencer

Accession Processed in 2006

CORRESPONDENCE

Scope and Content of Series

Series 4) CORRESPONDENCE: Arranged in three subseries: A) General, B) Incoming Email and C) Outgoing Email. The General Correspondence dates from 1964 to 1998 and includes correspondence from researchers and research institutions. The Incoming Email dates from 1988 to 1997. The Outgoing Email dates from 1989 to 1997.

General

Box 33 Folder 1
Canadian Institute for Advanced Research correspondence
Box 33 Folder 2
Correspondence (Fitch, Hampton, Laursen and Mawe), 1969 - 1970
Box 33 Folder 3
Correspondence with Dr. David Waxman, 1981
Box 33 Folder 4
Correspondence with Dr. Hawiger, 1980
Box 33 Folder 5
Correspondence with Dr. Walter
Box 33 Folder 6-19
1964 - 1977, June
Box 34 Folder 1-13
1977, July - 1983
Box 35 Folder 1-11
1984 - 1987
Box 36 Folder 1-13
1987 - 1991, September
Box 37 Folder 1-9
1991, October - 1994
Box 38 Folder 1-10
1995 - 1998
Box 39 Folder 1-8
1999 - 2003
Box 39 Folder 9
Ivan Rayment (collaboration)
Box 39 Folder 10
Letters from Russell F. Doolittle
Box 39 Folder 11
Old correspondence
Box 39 Folder 12
Patent Application, 1981
Box 39 Folder 13
Protein Folding Discussion Group, March-May, 1991
Box 39 Folder 14
Russell F. Doolittle mail and general instructions
Box 39 Folder 15
Sabbatical correspondence
Box 39 Folder 16
"Synthetic Peptide Antipolymerants of Fibrin" patent, March, 1982
Box 39 Folder 17
Uppsala University- Bioinformatics
Box 39 Folder 18
Virgil Woods' HIV Project: Detection and Characterization of Human Germline Incorporation of HIV-1
Box 39 Folder 19
Wei Duan's Thesis Exam

Incoming Email

Box 40 Folder 1-19
1988, January - 1993, April
Box 41 Folder 1-20
1993, May - 1995, January
Box 42 Folder 1-18
1995, February - 1996, May
Box 43 Folder 1-15
1996, June - 1997, August
Box 44 Folder 1-3
1997, September - 1997, November , 1997

Outgoing Email

Box 44 Folder 4
Human Genome Project newsletters, December, 1989-March, 1990
Box 44 Folder 5
1985 - 1988
Box 44 Folder 6-24
1988, May - 1996, March
Box 45 Folder 1-8
1996, April - 1997, December

LABORATORY NOTEBOOKS

Scope and Content of Series

Series 5) LABORATORY NOTEBOOKS: Arranged in two subseries: A) By Researcher and B) By Subject. The By Researcher subseries contains research notes by Doolittle's assistants and are arranged alphabetically. The By Subject subseries is arranged alphabetically by the topic being researched, for example, Peptide Synthesis, Biochemistry and Molecular Genetics.

By Researcher

Box 46 Folder 1
Abanes, De Mello, Angelica - Bio Rotation - FReP, September 23 - November 1, 1996
Box 46 Folder 2
Aldaz, Hector, July 1 - September 1, 1992
Box 46 Folder 3
Bouma, Bud - Daily Log, September 15 - December, 1975
Box 46 Folder 4
Bystroff, Chris - "Doolittle Lab" Summer Rotations, July - September, 1983

Cairns, Jim

Box 46 Folder 5
Book 1. Clotting Experiments-Peptide Purification, August 3 - November 30, 1993
Box 46 Folder 6
Book 2. Project PGPRV-Reagent Preparation, 1993 - 1994
Box 47 Folder 1
Book 3.The Continuing Saga of the Disulfide Ring Peptide (796), December 2, 1993 - June 22, 1994
Box 47 Folder 2
Book 4. Fragment E. Digestion/Disulfides, May 18, 1994 - January 11, 1995
Box 47 Folder 3
Book 5. Disulfide Ring Peptide, June 22-September 27, 1994

Chen, R

Box 47 Folder 4-5
Book 1: Chromatography of S-SO3 chains of BOV Phi F.XLF G-200 (6M urea) CM52, December-Feb., Dec. 1968 - Feb. 1970
Box 47 Folder 6
Book 2: Rabbit Light Chain Enzyme digestions and chromatography S-Sulfo Phi Chromatography and AAA, 1968
Box 47 Folder 7
Book 3: C14-Gee-"gamma" Bovine AAA, June 1969 - August 1971
Box 47 Folder 8
Book 4: B gamma C-14 GEE gamma Enzyme digestions Chromatograms Electrophoresis, June 1969 - December 1970
Box 47 Folder 9
Book 5: Bov crosslinking expts. Amino Acids Analysis, January 1969 - February 1970
Box 47 Folder 10
Book 6: Bov gamma-gamma TypeI trypsin Chromatography CM 52 G-100, July 1969 - July 1970
Box 47 Folder 11
Book 7: AAA of 14C HgammaGee peptides from chromatography & el. 14C Halpha peptides from chromatography & el., 1970
Box 47 Folder 12
Book 8: Human 14C GEE fibrin CM52 Trypsin digestion of H "gamma" G-25 electrophoresis, December 1969 - July 1970
Box 47 Folder 13
Book 9: HXLF GEE CM52 H&B XLphi Oklahoma F on CM52, 1970
Box 47 Folder 14
Book 10: Paper el. of: 14C Hgamma Th exp. mix control mis tryptic bovine gamma Oklahoma Pool 5 and bt glu-ala, 1970
Box 47 Folder 15
Book 11: Crosslinking experiments EDMANS, December 1969 - December 1970
Box 47 Folder 16
Book 12: Uvicon Scans of various Sephadex Columns Data from scintillation counters, 1970
Box 48 Folder 1-3
Cho, Glen - Preparation of phi and metal derivatives, 1995 - 1996
Box 48 Folder 4
Clason, G.W., and M.E. Riley - Enzymology, 1969 - 1970
Box 48 Folder 5
Clinton, Gail - Rotator, Phosphorylated Serine in Fibrinogen, 1969

Cottrell, B

Box 48 Folder 6
February, 1973 - December, 1974
Box 48 Folder 7
Hgamma CN3, Hgamma CNBC, Hgamma SC digest, December 1980
Box 48 Folder 8
February 1980 - January 1983
Box 48 Folder 9
Book 1. Project DNA Sequencing, October 29 - November 29, 1984
Box 48 Folder 10
Evans, Barbara R. - Lamprey Molecular Biology: Northerns and Southerns, September - October 1986

Everse, Stephen

Crystal Book

Box 48 Folder 11-14
Books 1-4, 1990 - 1994
Box 49 Folder 1-3
Books 5-7, 1994 - 1997
Box 49 Folder 4-6
Project 0 - Books 2-4, 1990 - 1991
Box 49 Folder 7-15
Project H0 - Books 5-13, 1991 - 1998
Box 49 Folder 16
Book 1. Rotation, January 5 - June 23, 1990
Box 50 Folder 1
Models, July 23, 1994 - July 11, 1998
Box 50 Folder 2
Fann, Wen-Pang

Feng, Da Fei

Box 50 Folder 3
August 1982 - July 1983
Box 50 Folder 4
April - October 1991
Box 50 Folder 5-6
CRB 233 UCSD, 1983 - 1985
Box 50 Folder 7-8
CRB 319 UCSD, 1985 - 1988
Box 50 Folder 9
Divergence, May 1994 - November 1999
Box 50 Folder 10
Gas Project, July 7, 1988 - December 1989
Box 50 Folder 11
Foreman/Freunal, Laura, November 1999 - May 2000

Gray, Jeff

Box 50 Folder 12
Book 1. Project Research, April 15, 1986 - February 2, 1987
Box 50 Folder 13
Book 2. Project Research, February 5 - October 20, 1987
Box 50 Folder 14
Book 3. Project 7n/3 535-5D, October 26, 1987 - October 6, 1988
Box 50 Folder 15
Book 4. Project LMPP/LFerritin/AlphaChains, September 1988 - October 27, 1989
Box 50 Folder 16
Book 5. Project Zamprey Album, November 1, 1989 - October 5, 1990
Box 51 Folder 1
Peptide Solubility versus composition/size, August 13 - October 22, 1986
Box 51 Folder 2
Book 1. Retroviral Gag Proteins and Related Sequences, October 15, 1985 - January 14, 1986
Box 51 Folder 3
October 1990 - March 1991
Box 51 Folder 4-6
Handy, Jacob, 1997 - 1999
Box 51 Folder 7
Haschemeyer, A. Visiting Scientist - Fibrinogen, March 1975

Healey, Carol

Box 51 Folder 8
Lipocalins/Fatty Acid Binding Proteins, April 9 - July 30, 1993
Box 51 Folder 9
Protinase Inhibitors PSTI Basic, August 2, 1993
Box 51 Folder 10
Hiroyuki, Tom, Winter 1992
Box 51 Folder 11
Huang, Mai, 1998 - 2000
Box 51 Folder 12
Hucko, Judy, 1974 - 1975
Box 51 Folder 13
Jacque, Jean - ATA, 1980 - 1981
Box 51 Folder 14-15
Johnson, Aaron, 1989 - 1990
Box 51 Folder 16
Kamps, Mark - (Rotator), Rotation 1, October - November, 1981
Box 51 Folder 17
Keil, Andrea - DNA/RNA Extraction, 1982
Box 51 Folder 18
Kuei, Debbie and Jung Wang - Biochemistry , May 5 - September 30, 1986
Box 51 Folder 19
Lane, Ray, Fall 1978
Box 51 Folder 20
Lau, Francis - Master's Lecture UCSD, April - September, 1970

Laudano, Andrew

Box 51 Folder 21
Book 1. Research, May 23 - September 13, 1977
Box 52 Folder 1
Book 2. Project Chemistry Research, September 14 - November 11, 1977
Box 52 Folder 2
Book 3. Project Chem Research, December 11, 1977 - June 22, 1978
Box 52 Folder 3
Book 4. Project Chemistry Research, June 24 - November 5, 1978
Box 52 Folder 4
Book 5. Project Chemistry Research, January 5 - January 27, 1978
Box 52 Folder 5
Book 6. Biochemistry Research, January 29 - March 26, 1979
Box 52 Folder 6
Book 7. Biochemistry Research, March 27 - June 20, 1979
Box 52 Folder 7
Book 8. Project Biochemistry Research, June 20 - October 15, 1979
Box 52 Folder 8
Book 9. Project: Chemistry Research, May 15 - December 23, 1979
Box 52 Folder 9
Book 10. Project Chemistry Research, December 22, 1979 - February 25, 1980
Box 52 Folder 10
Book 11. Biochemistry Research, February 25 - April 23, 1980
Box 52 Folder 11
Book 12. Project Biochemistry Research, April 24 - July 20, 1980
Box 52 Folder 12
Book 13. Biochemistry Research, July 21, 1980 - May 22, 1982
Box 52 Folder 13
Leong, Jane - Rotation, May 5 - June 7, 1989

Little, Elizabeth

Box 52 Folder 14
Book 1. Project Alpha-XL, October 1993 - February, 1994
Box 52 Folder 15
Book 1. Project Gels, November 29, 1993 - May 26, 1994
Box 52 Folder 16
Book 2. Project Alpha XL-2, February - June 1994
Box 52 Folder 17
Maffly, Bob, 1977 - 1978
Box 52 Folder 18
Maher, David - Rotation, May 1986
Box 52 Folder 19
Malden, Marx, December 26, 1991
Box 53 Folder 1
McAllister, Ryan - Percent identity/percent similarity data, Summer 1999
Box 53 Folder 2
Mross, George, 1975 - 1976

Nagel, Glenn

Box 53 Folder 3
#1, August 16 - May 30, 1990
Box 53 Folder 4
#2, June 4, 1990
Box 53 Folder 5
Nicewander, Penelope H., March 28 - July 1990

Subject: Sequences

Pan, Yang

Box 53 Folder 6
Book 1, April 29 - December 11, 1987
Box 53 Folder 7
Book 2, December 14, 1987 - October 29, 1988
Box 53 Folder 8
Book 3, November 1, 1988 - September 12, 1989
Box 53 Folder 9
Book 4, September 14, 1989 - April 27, 1990
Box 53 Folder 10
Book 5, May 1 - December 5, 1990
Box 53 Folder 11
Book 6, December 17, 1990 - August 28, 1991
Box 53 Folder 12
Book 7, August 30, 1991 - October 16, 1992
Box 53 Folder 13
Pankratz, Dan - Rotator, 1997 - 1998
Box 53 Folder 14
Patterson, John - Sequencing Alpha Chain Fibrinogen, 1987 - 1988
Box 53 Folder 15
Picknar, Kathy - Book 1. Rotation, September 26 - December 17, 1986

Pontes, Manuel

Box 53 Folder 16
Oligonucleotide Chemistry, January 16, 1981 - February 23, 1983
Box 53 Folder 17
April 16, 1981 - May 13, 1982
Box 54 Folder 1
Book 3. Molecular Biology, March 1, 1983 - January 3, 1984
Box 54 Folder 2
Book 4. Molecular Biology, January 9 - July 4, 1984
Box 54 Folder 3
Book 5. Molecular Biology, July 4, 1984 - June 5, 1985
Box 54 Folder 4
Book 6. Molecular Biology, June 11, 1985 - March 19, 1986
Box 54 Folder 5
Book 7. Molecular Biology, March 19 - May 28, 1986
Box 54 Folder 6
315 CRB, April 8 - December 2, 1985
Box 54 Folder 7
Project LMP 2, February 13 - July 19, 1986
Box 54 Folder 8
Rabbit Book - Immunocogy, 1974 - 1976
Box 54 Folder 9
Rhoades, Chris, June - July 1993

Riley, Marcia

Box 54 Folder 10
Human Genetics Program Project "Cost" Book, 1975 - 1979
Box 54 Folder 11
Human Genetics Program, 1975 - 1979
Box 54 Folder 12
Project E-Coli, March 1 - October 11, 1983
Box 54 Folder 13
Riley, M. and R. Doolittle, 1999 - 2000
Box 54 Folder 14-16
Rojas, Ana, 2000 - 2002
Box 54 Folder 17
Ryckewhert, 1983 - 1986

Shimizu, Akira

Box 55 Folder 1-3
Books 1-3. Photo Affinity Labeling, 1987 - 1989
Box 55 Folder 4
Peptide Synthesis, 1987 - 1989

Shipwash, Ed

Box 55 Folder 5
August 2, 1994 - April 19, 1995
Box 55 Folder 6
Book 1, August 2 - December 27, 1993
Box 55 Folder 7
Book 2. Project Alpha 2, 1993 - 1994
Box 55 Folder 8
Book 3, April 15 - May 16, 1994
Box 55 Folder 9
Project Tissue Factor, August 2 - September 8, 1993
Box 55 Folder 10
Thompson, Katie. Russell Doolittle lab, April 5 - July 1988
Box 55 Folder 11
Wetzel, Glenn, October 4 - December 16, 1978
Box 55 Folder 12
Wilson, Carolyn Anne. Project Brad Nolen, September 24 - December 11, 1992
Box 55 Folder 13
Wooding, Gretchen, June 1970

Xu, Xun

Box 55 Folder 14
February 22 - June 12, 1990
Box 55 Folder 15
Book 2, 1989 - 1990
Box 55 Folder 16
Project Sequence, 1985 - 1986

Yamazumi, Kensuke

Box 55 Folder 17
Book 1, 1990 - 1991
Box 56 Folder 1-3
Books 2-4. Photoaffinity labeling of frag. D1 with GPRK, 1991 - 1992
Box 56 Folder 4
Book 5. Photoaffinity labeling of frag. D1 with GPRC and GPRPK, 1991 - 1992
Box 56 Folder 5
Book 6. Photoaffinity labeling of frag. D1 with GHRPK and GHRK, 1992
Box 56 Folder 6
Book 7. Project GHRPx and GPRPnh2, May 26 - August 30, 1992

By Subject

Box 56 Folder 7
Phi CNI, PL1 TR AA Analyses, Peptides, GEE, A1 I - B. Cottrell, May - September 1978

Auto Solid Phase Peptide Synthesis

Box 56 Folder 8
No. 1, November 1983
Box 56 Folder 9
No. 2, April 4 - September 19, 1984
Box 56 Folder 10
No. 3, September 19, 1984 - February 14, 1985
Box 56 Folder 11
No. 4, February 15, 1985
Box 56 Folder 12
No. 5, undated
Box 57 Folder 1
No. 6, May 12, 1986
Box 57 Folder 2-5
Nos. 7-10, undated
Box 57 Folder 6
No. 11, August 1990 - July 1991
Box 57 Folder 7
No. 12, July 1991
Box 57 Folder 8-9
Nos. 13-14, undated
Box 57 Folder 10
Biology, Doolittle lab rotation - Rex Kerr, February - March 1997

Bohanus

Box 57 Folder 11
V.1, December 5, 1983 - April 17, 1984
Box 57 Folder 12
V.2, April 23 - September 23, 1984
Box 57 Folder 13
V.3, September 24, 1984
Box 57 Folder 14
V.4 - Beta Chain 2C 610, February 25, 1985
Box 58 Folder 1
cDNA Library - Book #5- Yu, Caroline, September - November 1986

Includes gel pictures and graphs

Box 58 Folder 2
cDNA Library - Book #6- Yu, Caroline, December 1986 - February 1987

Includes gel pictures and graphs

Box 58 Folder 3
Circular Dichrolsm Machine Log, May 1980 - February 1987
Box 58 Folder 4
Center for Molecular Genetics - Peptide Synthesizer 990, Igor Mochalkin
Box 58 Folder 5
CMG 213, GHRP-NH2 HPLC - Colin Aston, August 2, 2000
Box 58 Folder 6
Colony Hyb with Syn. Probes - Strong, D., March 1983

Includes X-Rays

Box 58 Folder 7
Computer Aided Protein Evolution Studies - Woodbury, Neil, June 1978
Box 58 Folder 8
Computer Guide - Woodbury, Neil
Box 58 Folder 9
Computer Maintenance - Woodbury, Neil, October 28, 1978
Box 58 Folder 10-13
DNA Sequence L Alpha 713-3D - Yu, Caroline, 1985 - 1986

Includes gel pictures

Box 58 Folder 14
E1 E2 E3 - Bgamma, Trypsin

Folder 2 of 2

Box 58 Folder 15
Electric Birefringence, E.B. Summary, EDTA EXPT - R. Doolittle & B. Cottrell, Summer 1974
Box 58 Folder 16
Fibrinogen Preparations, Human, Lamprey, Mule, Opossum, Boxine, Rabbit, Rat, Mouse, Sheep. Includes graphs - Riley, Marcia, Russell Doolittle and Barbara Cottrell et. al., September 1972 - December 1976
Box 58 Folder 17
Fibrinopeptides-Part 1-Doolittle, Russell, et. al., 1968 - 1969

March-September. Mandrill, Chimpanzee, Collared Peccary, Mouflon, White Fallow Deer, Golden Jackal, South American Tapir. Including C. Glasgow. Contains graphs.

Box 59 Folder 1
Fibrinopeptides-Part 2-Doolittle, Russell, et. al., 1968 - 1969

March-September. Mandrill, Chimpanzee, Collared Peccary, Mouflon, White fallow Deer, Golden Jackal, South American Tapir. Including C. Glasgow. Contains graphs.

Box 59 Folder 2
Fragment E, R and A, E1E2E3, RD/SD/BC, September, 1978

Folder 1 of 2

Box 59 Folder 3
Gel Book #2- Riley, Marcia, 1987 - 1988

November-September. Includes gel photos.

Genomic Library L Alpha B1

Box 59 Folder 4
Book #7- Yu, Caroline, 1987

March-July. Includes gel pictures.

Box 59 Folder 5
Book #8- Yu, Caroline, 1987

July-August. Includes gel pictures.

Box 59 Folder 6
Hgamma, HgammaCN3+4, Trypsin, January, 1981
Box 59 Folder 7
H alpha CNI, GLU Beads, Pools 4-7, 4-7
Box 59 Folder 8
HPLC
Box 59 Folder 9
Human Cross- Link Fibrin - Doolittle, R. F. and Barbara Cottrell., 1978 - 1979

June-January. Includes graphs.

Box 59 Folder 10
Human Fibrinogen, Alpha Chain CNBr, April-January, 1975 - 1979

Cottrell, Barbara and Marcia Riley, et. al. and Human Fibrinogen Alpha Chain CNBr, 1976 July- Cottrell, Barbara. Includes graphs.

Box 59 Folder 11
Human Fibrinogen Sequences, Alpha Chain CNBR-Cottrell, Barbara., 1975 - 1978

December-March. Includes graphs.

Box 59 Folder 12
Human Fibrinogen, Alpha Chain CN-5-Part 1- Cottrell, Barbara, 1975 - 1976

July-March. Includes graphs

Box 59 Folder 13
Human Fibrinogen, Alpha Chain CN-5-Part 2- Cottrell, Barbara, 1975 - 1976

July-March. Includes graphs.

Box 59 Folder 14
Human Fibrinogen, Alpha Chain CNBr GEE- Strong, Donna and Cottrell, Barbara, 1978 - 1979

October-June. Includes graphs.

Box 60 Folder 1
Human Fibrinogen, Alpha Chain, CNBr, PL - Strong, Donna., 1978

May-October. Includes graphs.

Box 60 Folder 2
Human Fibrinogen, Alpha Chain CNBr, Staph Protease - Cottrell, Barbara., 1978 - 1979

November-February. Includes graphs.

Box 60 Folder 3
Insert Gel Book- Riley, Marcia, 1985 - 1987

February-October. Includes gel pictures.

Box 60 Folder 4
JJR, June, 1982

Lab Notebook

Box 60 Folder 5-9
Cooke, Tracy, 1988

September-December

Box 60 Folder 10
Graham, David, 1987

Includes gel pictures

Box 60 Folder 11
Yu, Caroline, April 1, 1985
Box 60 Folder 12-13
Yu-then, Wang

Undated. Includes gel pictures.

Box 60 Folder 14-15
Lamprey Albumin, cDNA - Gray, Jeff, 1988 - 1990

December-May

Box 60 Folder 16
Lamprey Liver, c-DNA Screening, June-July, 1984 - 1986

Doolittle Lab

Box 60 Folder 17
LEECH Hirudin Prep. - Doolittle, R. F., et. al., 1977 - 1978

October-May. Includes graphs.

Box 61 Folder 1
Lobster and Fibrinogen, July-May, 1972 - 1973

B. Cottrell, K. Cassman

Box 61 Folder 2
Log-Manoj-George, Summer, 1987
Box 61 Folder 3
'Matt' Rotation, February, 1993
Box 61 Folder 4
Molecular Genetics HPLC THUC TO
Box 61 Folder 5
More Programs for the PDP 11/04- Woodbury, Neil, March, 1979
Box 61 Folder 6
New Juno, February 19, 1993
Box 61 Folder 7
Nicewander, Penelope N., January 8, 1990
Box 61 Folder 8
Notes on Computer 1- Goyal, Manoj, April 24, 1987
Box 61 Folder 9-10
Oligonucleotide Synthesis, 1982 - 1983

Lab methods and summary

Box 61 Folder 11
PDP 11/04 Notes and Programs- Woodbury, Neil, March-March, 1978 - 1979
Box 61 Folder 12
Restriction Enzyme and Plasmid Inventories- Ellis, Carmen and Lisa Phanton, 1984 - 1986

October-December

Box 61 Folder 13
Rotations Fall, 1996
Box 61 Folder 14
Setting up Mini-Unix-Sixth Addition
Box 61 Folder 15
Smith, Mike, Spring, 1991
Box 61 Folder 16
Smith, M.W.

Staph Clumping Factor

Box 61 Folder 17
Strong, D., 1980

February-May. Includes graphs and pictures.

Box 61 Folder 18
Fragment D, etc. - Part 1- Strong, D., et. al., 1981

March-June. Includes graphs.

Box 62 Folder 1
Fragment D, etc. - Part 2- Strong, D., et. al., 1981

March-June. Includes graphs.

Box 62 Folder 2
TATG Lob phi, 1980
Box 62 Folder 3
TATG Synthesis- Woods, Virgil and Russell Doolittle, George Moss, and John Sharp., 1973 - 1975

July-March

Box 62 Folder 4
Variant Human Fibrinogen ("D.MARR"), Thrombin-Inhibitors-Weinstein, Mark and Russell Doolittle., 1971 - 1972

May-May. Contains graphs.

Box 62 Folder 5
Vax Log-Zeus, Johnson, M., June 17, 1985
Box 62 Folder 6
Webb, Jenn, April 1, 2002
Box 62 Folder 7
Weigh Book, Doolittle, August-December, 1965 - 1973

Xun Xu

Box 62 Folder 8
cDNA Sequencing (1) LMPI, June 3-October 1, 1985
Box 62 Folder 9
M13 Sequence (3), 1986
Box 63 Folder 1
M.D., 1989
Box 63 Folder 2
Sequence 4, 1986
Box 63 Folder 3
Zeus Backup Log, mag-Tape Cleaning Log- Doolittle and Johnson, July 23, 1985