Fawcett, Don W. (2021). CIL:10978, Cavia porcellus, plasma cell. In Cell Image Library. UC San Diego Library Digital Collections. Dataset. https://doi.org/10.6075/J06Q1W14

Transmission electron micrograph illustrating the accumulation of dense heterochromation that accompanies terminal differentiation in may cells. Shown here is a section through a polychromatophilic erythroblast from guinea pig bone marrow. The exclusion of heterochromatin from nuclear pore regions is clearly seen. Figure 115 from Chapter 4 (Nucleus) of 'The Cell, 2nd Ed.' by Don W. Fawcett M.D. A PDF copy of the corresponding chapter is available on the ASCB's BioEDUCATE website.

• 2021

• Fawcett, Don W.

Preparation: tissue in plastic embedment; osmium tetroxide fixed tissue; glutaraldehyde fixed tissue
Relation to intact cell: microtome-sectioned tissue
Item type: film
Imaging mode: transmission electron microscopy (TEM); detection of electrons
Parameter imaged: electron density
Source of contrast: differences in adsorption or binding of stain
Visualization methods: uranyl salt; osmium tetroxide; lead salt
Processing history: Image extracted from .pdf file of 'The Cell'
Data qualification: Processed

• Cell Image Library Group ID: 11224

• Cavia porcellus

• Chromatin
• Heterochromatin
• Nuclear envelope
• Nuclear pore
• Nucleus
• Plasma cell

• Adaptive immune response
• Chromatin organization
• Immunoglobulin secretion involved in immune response
• Nucleus organization

• data
• image

• No linguistic content; Not applicable

Samplenumber: 10978

Doi: https://doi.org/10.6075/J06Q1W14

Source data

• Source Record in the Cell Image Library: https://doi.org/10.7295/W9CIL10978

Other resource

• Fawcett, Don W. "The Cell." 2nd ed., W.B. Saunders, 1981, ISBN 0721635849. https://www.ascb.org/career-development/teaching/don-fawcetts-the-cell/

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2022-08-12