Microscopy product ID: 3946
Single computed slice through a tomographic reconstruction of a virological synapse formed between naturally HTLV-1 infected CD4+ T cells and autologous uninfected CD4+ target cells. HTLV-1 particles in the synaptic cleft were identified by immunolabeling using anti-Gag p19 labeling and peroxidase-DAB detection.
Full resolution data file
Serial tomographic 3D volume composed of tomograms obtained from five serial sections in MRC format. The tomogram represents a volume with an area of 1.55╫2.66 ╡m2 and a thickness of 343 nm. Filename is map_3946.ccp4
Animation through computed slices of a serial tomographic reconstruction of a virological synapse formed between naturally HTLV-1 infected CD4+ T cells and autologous uninfected CD4+ target cells. HTLV-1 particles in the synaptic cleft were identified by immunolabeling using anti-Gag p19 labelling and peroxidase-DAB detection.
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- Project: 2004-02-02 to 2007-06-30.
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- Technical Details
Product type: SINGLE TILT. Microscopy type: TEM. Instrument: FEI Tecnai F30 FEG
- Related Publications
Majorovits E, Nejmeddine M, Tanaka Y, Taylor GP, Fuller SD, Bangham CRM (2008). Human T-lymphotropic virus-1 visualized at the virological synapse by electron tomography. PLoS ONE 3(5):e2251. doi: 10.1371/journal.pone.0002251 PMCID: PMC2386264
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- UC Regents
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