Schuller, S. (2021). CIL:38936, Shigella, Homo sapiens, intestinal epithelial cell. In Cell Image Library. UC San Diego Library Digital Collections. Dataset. https://doi.org/10.6075/J0H130VS

Confocal micrograph showing Shigella bacteria (pink) invading the intestinal lining. The bacteria infects the cells by high-jacking the cell's internal actin skeleton (green) to facilitate its entry into the cell and spread into adjoining cells, using polymerizing actin comet tails as several can be seen doing here. Shigella intestinal infection causes diarrhea and rapid dehydration typical of bacterial dysentery. FITC-labelled phalloidin highlights the actin of the cytoskeleton in green and propidium iodide (a DNA stain) was used to visualise bacteria in pink.

• 2021

• Schuller, S.

B0006238 Shigella infection. Wellcome Images available under the following creative commons usage http://creativecommons.org/licenses/by-nc-nd/2.0/uk/

Preparation: chemically fixed tissue
Item type: recorded image
Imaging mode: confocal microscopy
Parameter imaged: fluorescence microscopy
Source of contrast: distribution of epitope
Visualization methods: propidium iodide; phalloidin; Fluorescein (FITC)

• Homo sapiens
• Shigella

• Actin cytoskeleton
• DNA
• Intestinal epithelial cell

• Actin polymerization-dependent cell motility
• Bacterial invasion
• Diarrhea
• Shigellosis

• data
• image

• No linguistic content; Not applicable

Samplenumber: 38936

Doi: https://doi.org/10.6075/J0H130VS

Source data

• Source Record in the Cell Image Library: https://doi.org/10.7295/W9CIL38936

Other resource

• Wellcome Images: http://images.wellcome.ac.uk/

Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International Public License

• UC Regents

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2022-08-12