Fawcett, Don W. (2021). CIL:10948, Rattus, myelinating Schwann cell, peripheral neuron. In Cell Image Library. UC San Diego Library Digital Collections. Dataset. https://doi.org/10.6075/J0PG1QJQ

Electron micrograph of a nerve from the mesentery of a rat shows groups of unmyelinated axons wrapped by deeply invaginating Schwann cells in cross section. Surrounding the Schwann cell wrapping is a secreted basement membrane (known as the lamina externa, or boundary layer), similar to the basal lamina produced by epithelial cells. Figure 25 from Chapter 1 (The Cell Surface) of 'The Cell, 2nd Ed.' by Don W. Fawcett M.D. A PDF copy of the accompanying chapter is available on the ASCB's BioEDUCATE website.

• 2021

• Fawcett, Don W.

Preparation: crosslinking-fixative fixed tissue
Relation to intact cell: microtome-sectioned tissue
Item type: transmission electron microscopy (TEM)
Imaging mode: illumination by electrons; detection of electrons
Parameter imaged: electron density
Source of contrast: stain with broad specificity
Visualization methods: electron-dense stain
Data qualification: Processed

• Cell Image Library Group ID: 10550

• Rattus

• Axon
• Basement membrane
• Extracellular region part
• Myelinating Schwann cell
• Peripheral neuron
• Plasma membrane

• Basement membrane organization
• Cell-substrate adhesion
• Extracellular structure organization

• data
• image

• No linguistic content; Not applicable

Samplenumber: 10948

Doi: https://doi.org/10.6075/J0PG1QJQ

Source data

• Source Record in the Cell Image Library: https://doi.org/10.7295/W9CIL10948

Other resource

• Fawcett, Don W. "The Cell." 2nd ed., W.B. Saunders, 1981, ISBN 0721635849. https://www.ascb.org/career-development/teaching/don-fawcetts-the-cell/

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2025-01-30