Fawcett, Don W.; Heuser, John; Reese, Tom (2021). CIL:36012, Anura, peripheral neuron, muscle cell, myelinating Schwann cell. In Cell Image Library. UC San Diego Library Digital Collections. Dataset. https://doi.org/10.6075/J03J3BR1

Figure 394 from Chapter 15 (Cytoplasmic Inclusions) of 'The Cell, 2nd Ed.' by Don W. Fawcett M.D. "Omega figures" capturing synaptic vesicle exocytosis at the synaptic junction. This event was observed during chemical stimulation of the frog neuromuscular junction, prepared by rapid freezing with liquid helium followed by freeze substition. 4-aminopyridine was used to trigger release of the neurotransmitter acetylcholine.Image by John Heuser and Tom Reese. A PDF copy of the accompanying chapter is available on the ASCB’s BioEDUCATE website.

• 2021

• Fawcett, Don W.
• Heuser, John
• Reese, Tom

Preparation: crosslinking-fixative fixed tissue; tissue in plastic embedment
Relation to intact cell: microtome-sectioned tissue
Item type: transmission electron microscopy (TEM)
Imaging mode: illumination by electrons; detection of electrons
Parameter imaged: electron density
Source of contrast: stain with broad specificity
Visualization methods: osmium tetroxide
Data qualification: Processed

• Cell Image Library Group ID: 9896

• Anura

• Muscle cell
• Myelinating Schwann cell
• Neuromuscular junction
• Peripheral neuron
• Synapse
• Synaptic vesicle

• Synapse organization
• Synaptic vesicle exocytosis

• data
• image

• No linguistic content; Not applicable

Samplenumber: 36012

Doi: https://doi.org/10.6075/J03J3BR1

Source data

• Source Record in the Cell Image Library: https://doi.org/10.7295/W9CIL36012

Other resource

• Fawcett, Don W. "The Cell." 2nd ed., W.B. Saunders, 1981, ISBN 0721635849. https://www.ascb.org/career-development/teaching/don-fawcetts-the-cell/

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2022-08-12