Farquhar, Marilyn G. (2021). CIL:37180, Rattus, kidney cell, glomerular capillary endothelial cell, podocyte. In Cell Image Library. UC San Diego Library Digital Collections. Dataset. https://doi.org/10.6075/J0QN65D7

Transmission electron micrograph of rat kidney filtration barrier. Micrograph illustrates the basement membrane between fenestrated capillary endothelium and podocyte foot processes at intermediate magnification. The series of images in this group have particular historic and cell biologic importance for determining the role of the glomerular basement membrane in urinary filtration, especially the charge properties and size selectivity in retention of proteins in the circulation. The images here clearly show the glomerular filtration barrier. The study also elucidated the role of the basement membrane in some forms of nephrosis. Image made available by James D. Jamieson and the Department of Cell Biology, Yale University School of Medicine.

• 1963-07-01

• 2021

• Farquhar, Marilyn G.

Relevant citations:
Kanwar, Y.S. and M.G. Farquhar. 1979. J. Cell Biol. 81:137-153.
Farquhar, M.G., S.L. Wisssig and G.E. Palade. 1961 . J. Exp. Med. 113:47-66.

Original 3.25 in. x 4 in. lantern slides were scanned at 600dpi. Original magnification X19,000.

Preparation: osmium tetroxide fixed tissue
Relation to intact cell: sectioned tissue
Item type: recorded image
Imaging mode: transmission electron microscopy (TEM)
Parameter imaged: electron density
Source of contrast: differences in adsorption or binding of stain

• Cell Image Library Group ID: 10005

• Rattus

• Basement membrane
• Glomerular capillary endothelial cell
• Kidney cell
• Podocyte

• Glomerular filtration

• data
• image

• No linguistic content; Not applicable

Samplenumber: 37180

Doi: https://doi.org/10.6075/J0QN65D7

Source data

• Source Record in the Cell Image Library: https://doi.org/10.7295/W9CIL37180

Other resource

• George E. Palade EM Slide Collection: https://library.medicine.yale.edu/find/palade

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2023-08-17