Perlstein, Ethan; Korostyshevsky, Daniel (2021). CIL:40431, Saccharomyces cerevisiae, derived from S288c. In Cell Image Library. UC San Diego Library Digital Collections. Dataset. https://doi.org/10.6075/J0JD4VNX

Transmision electron micrograph of a representative sertraline-treated wildtype prototrophic cell (derived from S288c). A mature autophagosome is located in the upper-left. (6,300X). Untreated control image is avaialble as CIL 40432.

• 2021

• Korostyshevsky, Daniel
• Perlstein, Ethan

This group of images contains representative whole-cell images and high-magnification zooms of organelle structures of interest. All cells were grown in liquid rich media (YPD pH6.5) at 30C with aerated shaking, and cultures were sampled in mid-logarithmic phase. Treated cells were exposed to 60µM antidepressant sertraline (Zoloft®) for 45 minutes.

Preparation: glutaraldehyde fixed tissue; tissue in plastic embedment
Relation to intact cell: sectioned tissue
Item type: recorded image
Imaging mode: transmission electron microscopy (TEM)
Parameter imaged: electron density
Source of contrast: differences in adsorption or binding of stain
Visualization methods: osmium tetroxide
Processing history: unprocessed raw data

• Cell Image Library Group ID: 11316

• Saccharomyces cerevisiae

• Autophagic vacuole
• Derived from S288c
• Nucleus

• Organelle organization
• Sertraline treatment

• data
• image

• No linguistic content; Not applicable

Samplenumber: 40431

Doi: https://doi.org/10.6075/J0JD4VNX

Source data

• Source Record in the Cell Image Library: https://doi.org/10.7295/W9CIL40431

Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International Public License

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2022-08-12