Microscopy product ID: 9525
Reconstruction
Description | Transmission electron microscopic (TEM) overview of a glomerular section. Shown section is a consecutive section to the RCM section (MP9526). Specific RCM reflection is correlated with staining of albumin in this TEM overview. Chronic infusion of hyaluronidase leads to degradation of the glycocalyx. This results in the presence of albumin (dark black spots) bound to podocyte foot processes and on podocyte body and parietal epithelial cells. The sample has been imaged at 1.2 nm pixel-1 resolution over an area of 124 x 170 ╡m2. |
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Description | Tiff file of a transmission electron microscopic (TEM) overview of a glomerular section from the HA treatment group. Shown section is a consecutive section to the RCM section (MP9526). Specific RCM reflection is correlated with staining of albumin in this TEM overview. The sample has been imaged at 1.2 nm pixel-1 resolution over an area of 124 x 170 ╡m2. |
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van den Berg, Bernard M.; Rabelink, Ton J.; Dane, Martijn J. C.; van den Berg, Bernard M.; Avramut, M. Cristina; Faas, Frank G. A.; van der Vlag, Johan; Rops, Angelique L. W. M. M.; Ravelli, Raimond R. G.; Koster, Abraham J.; van Zonneveld, Anton Jan; Vink, Hans; Rabelink, Ton J. (2017). Microscopy product ID: 9525. In Cell Centered Database. UC San Diego Library Digital Collections. https://doi.org/10.6075/J0MP533D
- Creation Date
- Experiment: 2011-01-01. Project: 2009-09-01 to 2013-09-01.
- Date Issued
- 2017
- Research Team Heads
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- Technical Details
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Male. Strain: C57BL/6
Product type: MOSAIC. Microscopy type: TEM. Instrument: Transmission Electron Microscope
- Funding
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Dutch Kidney Foundation
- Series
- Scientific Name
- Anatomy
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- No linguistic content; Not applicable
- Related Resources
- Dane MJC, van den Berg BM, Avramut MC, Faas FGA, van der Vlag J, Rops ALWMM, Ravelli RBG, Koster BJ, van Zonneveld AJ, Vink H, Rabelink TJ (2013). Glomerular endothelial surface layer acts as a barrier against albumin filtration. Am J Pathol, 182(5):1532-1540. PubMed: https://www.ncbi.nlm.nih.gov/pubmed/23518410; American Journal of Patholology. https://doi.org/10.1016/j.ajpath.2013.01.049
- Microscopy product 9525 at the Cell Centered Database: https://doi.org/10.7295/W9CCDB9525
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Creative Commons Attribution 4.0 International Public License
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- UC Regents
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Under copyright (US)
Use: This work is available from the UC San Diego Library. This digital copy of the work is intended to support research, teaching, and private study.
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Research Data Curation Program, UC San Diego, La Jolla, 92093-0175 (https://lib.ucsd.edu/rdcp)
- Last Modified
2023-05-22