Microscopy product ID: 9525
Transmission electron microscopic (TEM) overview of a glomerular section. Shown section is a consecutive section to the RCM section (MP9526). Specific RCM reflection is correlated with staining of albumin in this TEM overview. Chronic infusion of hyaluronidase leads to degradation of the glycocalyx. This results in the presence of albumin (dark black spots) bound to podocyte foot processes and on podocyte body and parietal epithelial cells. The sample has been imaged at 1.2 nm pixel-1 resolution over an area of 124 x 170 ╡m2.
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Tiff file of a transmission electron microscopic (TEM) overview of a glomerular section from the HA treatment group. Shown section is a consecutive section to the RCM section (MP9526). Specific RCM reflection is correlated with staining of albumin in this TEM overview. The sample has been imaged at 1.2 nm pixel-1 resolution over an area of 124 x 170 ╡m2.
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- Creation Date
- Experiment: 2011-01-01. Project: 2009-09-01 to 2013-09-01.
- Scientific Name
- Technical Details
Male. Strain: C57BL/6
Product type: MOSAIC. Microscopy type: TEM. Instrument: Transmission Electron Microscope
- Related Publications
Dane MJC, van den Berg BM, Avramut MC, Faas FGA, van der Vlag J, Rops ALWMM, Ravelli RBG, Koster BJ, van Zonneveld AJ, Vink H, Rabelink TJ (2013). Glomerular endothelial surface layer acts as a barrier against albumin filtration. Am J Pathol, 182(5):1532-1540. doi: 10.1016/j.ajpath.2013.01.049 PMID: 23518410
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Research Data Curation Program, UC San Diego, La Jolla, 92093-0175 (https://lib.ucsd.edu/rdcp)
Dutch Kidney Foundation
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