Hahn, Klaus (2021). CIL:238, Mus musculus, fibroblast. In Cell Image Library. UC San Diego Library Digital Collections. Dataset. https://doi.org/10.6075/J0765DMM

The image depicts a live neutrophil cell showing the level of activation of the signaling protein Cdc42, a member of the Rho family of small guanosine triphosphatase (GTPase) proteins which regulates multiple cell functions, including motility, proliferation, apoptosis, and cell morphology. Here, the fluorescence level is related to protein conformational changes and interactions, with warmer colors indicating higher levels of activation. Cdc42 appears to be activated at cell protrusions.

• 2021

• Hahn, Klaus

See P. Nalbant et al 2004. Activation of endogenous Cdc42 visualized in living cells. Science 305:1615-1619.

Preparation: living tissue
Relation to intact cell: whole mounted tissue
Item type: recorded image
Imaging mode: fluorescence microscopy
Parameter imaged: fluorescence emission
Source of contrast: differences in protein conformation
Data qualification: Processed

• Cell Image Library Group ID: 8976

• Mus musculus

• Cdc2
• Fibroblast

• MEF

• data
• image

• No linguistic content; Not applicable

Samplenumber: 238

Doi: https://doi.org/10.6075/J0765DMM

Source data

• Source Record in the Cell Image Library: https://doi.org/10.7295/W9CIL238

Other resource

• NIGMS Image and Video Gallery: https://images.nigms.nih.gov/

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Research Data Curation Program, UC San Diego, La Jolla, 92093-0175 (https://lib.ucsd.edu/rdcp)

2022-08-12