Fawcett, Don W.; Gilula, Norton; Karnovsky, Morris; Aoki, A.; Wade, J.B.; Dym, Martin (2021). CIL:11193, Rattus, Ovis aries, Sertoli cell. In Cell Image Library. UC San Diego Library Digital Collections. Dataset. https://doi.org/10.6075/J05M64J9

Occluding junctions in Sertoli cells of ram and rat testis. Multiple focal sites of membrane fusion are indicated by arrows in each panel. Underlying these sites, associated bundles of filaments and typical subsurface cisternae are apparent in panels A, B and D. A, B, C from Gilula, Fawcett and Aoki, Dev. Biol. 50: 142068, 1976; D, Dym and Fawcett, Biol. Reprod. 3: 308-26, 1970; Inset from Wade and Karnovsky, J. Cell Biol., 60:168-91 illustrates two models regarding the relationship between the two cell membranes at these junctions. Regions indicated by asterisks in the micrograph in panel C support model "A." Micrographs reprinted with permission as Figure 69 from Chapter 3 (Junctional Specializations) of 'The Cell, 2nd Ed.' by Don W. Fawcett M.D. A PDF copy of the accompanying chapter is available on the ASCB's BioEDUCATE website.

• 2021

• Aoki, A.
• Dym, Martin
• Fawcett, Don W.
• Gilula, Norton
• Karnovsky, Morris
• Wade, J.B.

Preparation: crosslinking-fixative fixed tissue; tissue in plastic embedment
Relation to intact cell: microtome-sectioned tissue
Item type: transmission electron microscopy (TEM)
Imaging mode: illumination by electrons; detection of electrons
Parameter imaged: electron density
Source of contrast: stain with broad specificity
Visualization methods: osmium tetroxide
Data qualification: Processed

• Cell Image Library Group ID: 11071

• Ovis aries
• Rattus

• Occluding junction
• Sertoli cell

• Cell junction organization

• data
• image

• No linguistic content; Not applicable

Samplenumber: 11193

Doi: https://doi.org/10.6075/J05M64J9

Source data

• Source Record in the Cell Image Library: https://doi.org/10.7295/W9CIL11193

Reference

• Dym & Fawcett (1970) Biol. Reprod. 3:308-326. http://www.biolreprod.org/content/3/3/308.long
• Dym M, Fawcett DW. The blood-testis barrier in the rat and the physiological compartmentation of the seminiferous epithelium. Biol Reprod. 1970 Dec;3(3):308-26. https://doi.org/10.1093/biolreprod/3.3.308
• Gilula NB, Fawcett DW, Aoki A. The Sertoli cell occluding junctions and gap junctions in mature and developing mammalian testis. Dev Biol. 1976 May;50(1):142-68. https://doi.org/10.1016/0012-1606(76)90074-9
• James B. Wade, Morris J. Karnovsky; Fracture faces of osmotically disrupted zonulae occludentes . J Cell Biol 1 August 1974; 62 (2): 344–350. doi: https://doi.org/10.1083/jcb.62.2.344
• PubMed article: <@ https://www.ncbi.nlm.nih.gov/pubmed/?term=269826
• PubMed article: <@ https://www.ncbi.nlm.nih.gov/pubmed/?term=4108372
• PubMed article: <@ https://www.ncbi.nlm.nih.gov/pubmed/?term=4473455

Other resource

• Fawcett, Don W. "The Cell." 2nd ed., W.B. Saunders, 1981, ISBN 0721635849. https://www.ascb.org/career-development/teaching/don-fawcetts-the-cell/

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2022-08-12