Hu, Jiaxin; Dodd, David; Hudson, Robert (2021). CIL:220, Mus musculus, neuron. In Cell Image Library. UC San Diego Library Digital Collections. Dataset. https://doi.org/10.6075/J0JM28VW

Molecules designed to block the expanded CAG repeats characteristic of Huntington's disease fluoresce blue in these cultured cells and prevent the expression of the mutant proteins that cause the disease.

• 2021

• Dodd, David
• Hu, Jiaxin
• Hudson, Robert

See: J. Hu et al.(2009) Allele-specific silencing of mutant huntintin and ataxin-3 genes by targeting expanded CAG repeats in mRNAs. Nat Biotechnol 27:478-484.

Relation to intact cell: whole mounted tissue
Item type: recorded image
Imaging mode: fluorescence microscopy
Parameter imaged: fluorescence emission
Data qualification: Processed

• Mus musculus

• Neuron

• Huntington's disease

• data
• image

• No linguistic content; Not applicable

Samplenumber: 220

Doi: https://doi.org/10.6075/J0JM28VW

Source data

• Source Record in the Cell Image Library: https://doi.org/10.7295/W9CIL220

Other resource

• NIGMS Biomedical Beat (2018-09-06): https://biobeat.nigms.nih.gov

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2022-08-12