Natural history of pediatric patients with eosinophilic esophagitis

• Restricted to UC San Diego use only

Eosinophilic esophagitis (EoE) is a chronic immune/antigen mediated disease of the esophagus that presents with inflammatory and fibrotic features. Patients of all ages are afflicted. Affected patients can present with debilitating symptoms such as feeding problems, dysphagia and food impaction. Since its initial characterization in the 1990s, EoE has been increasingly recognized in both adult and pediatric patients. As a result of increasing awareness of the disease, there is a growing body of literature focused on better understanding EoE pathophysiology, clinical presentation, and treatment options. However, due to its recent recognition, few studies have been able to adequately examine the natural history EoE over a substantial period of time. These studies are particularly lacking within the pediatric population. Objectives: 1) further characterize the natural history with respect to treatment response in the EoE pediatric population; 2) identify subtypes within the database population that resond differently to various treatment modalities; 3) ascertain clinical, endoscopic, and histologic similarities and differences between these subtypes

• 2018

• Palmquist, Jacob

1 online resource (4 unnumbered pages) : illustrations (some color)

Description based on online resource; title PDF cover page (viewed May 23, 2019)

Forms part of the UC San Diego School of Medicine independent study projects, Class of 2018

Includes bibliographical references

Title provided by the cataloger

• Academic Dissertations

• Dissertations, Academic--School of Medicine. (Discipline)--UCSD

• text

• English

La Jolla, California: University of California, San Diego

M.D. University of California, San Diego 2018

• Palmquist, Jacob

Under copyright (US)

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2020-10-26