Palade, George E. (2021). CIL:37186, Rattus, hepatocyte. In Cell Image Library. UC San Diego Library Digital Collections. Dataset. https://doi.org/10.6075/J0HT2MZ4

Transmission electron micrograph of thin section of rat liver with prominent Golgi and smooth ER associated vesicles. At lower right, the junction between hepatocytes harbors a bile canaliculus. The image illustrates the ethanol-stimulated accumulation of low density lipoprotein (LDL) in Golgi of the liver in rats fed ethanol (equivalent to 1 quart of single malt whisky) by gastric tube. This observation was the impetus for the strategy of purifying Golgi factions by allowing them to rise the surface of dense sucrose columns. Image made available by James D. Jamieson and the Department of Cell Biology, Yale University School of Medicine.

• 2021

• Palade, George E.

Original 3.25 in. x 4 in. lantern slides were scanned at 600dpi. Original Magnification: x19,000.

Preparation: chemically fixed tissue
Relation to intact cell: sectioned tissue
Item type: recorded image
Imaging mode: transmission electron microscopy (TEM)
Parameter imaged: electron density
Source of contrast: differences in adsorption or binding of stain
Visualization methods: osmium tetroxide
Processing history: unprocessed raw data

• Cell Image Library Group ID: 11083

• Rattus

• Cell-cell junction
• Golgi apparatus
• Hepatocyte
• Low-density lipoprotein particle
• Mitochondrion
• Smooth endoplasmic reticulum

• LDL accumulation

• data
• image

• No linguistic content; Not applicable

Samplenumber: 37186

Doi: https://doi.org/10.6075/J0HT2MZ4

Source data

• Source Record in the Cell Image Library: https://doi.org/10.7295/W9CIL37186

Other resource

• George E. Palade EM Slide Collection: https://library.medicine.yale.edu/find/palade

Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International Public License

• UC Regents

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2022-08-12