Rudinska, M. (2021). CIL:37193, Plasmodium. In Cell Image Library. UC San Diego Library Digital Collections. Dataset. https://doi.org/10.6075/J0MG7N45

Transmission electron micrograph of a mitochondria from the protist Plasmodium. The use of osmium tetroxide as a fixative for electron microscopy was first described by Dr. Palade at the Rockefeller. Another major advance in fixation for electron microscopy was done at Yale by David Sabatini who described the use of glutaraldehyde which not only preserved ultrastructure, but enzymatic activities which opened up the possibility of EM localization of enzymatic function in cells. Image made available by James D. Jamieson and the Department of Cell Biology, Yale University School of Medicine.

• 1958-02-05

• 2021

• Rudinska, M.

References:
Palade, G.E. 1952. J. Exp. Med. 95:285-298.
Palade, G.E. 1952. Anat. Rec. 114:427-451.
Sabatini, D.D, K. Bensch and R.J. Barrnett. 1963. J. Cell. Bio. 17:19-58.
Original 3.25 in. x 4 in. lantern slides were scanned at 600dpi. Original magnification X15,000.

Preparation: osmium tetroxide fixed tissue
Relation to intact cell: sectioned tissue
Item type: recorded image
Imaging mode: transmission electron microscopy (TEM)
Parameter imaged: electron density
Source of contrast: differences in adsorption or binding of stain

• Cell Image Library Group ID: 10000

• Plasmodium

• Mitochondrial crista
• Mitochondrial membrane
• Mitochondrion

• data
• image

• No linguistic content; Not applicable

Samplenumber: 37193

Doi: https://doi.org/10.6075/J0MG7N45

Source data

• Source Record in the Cell Image Library: https://doi.org/10.7295/W9CIL37193

Other resource

• George E. Palade EM Slide Collection: http://cushing.med.yale.edu/gsdl/cgi-bin/library?c=palade&a=d&d=DpaladeLivJ

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2023-08-17