Osinska, Hanna (2021). CIL:252, Mus musculus, skeletal muscle cell. In Cell Image Library. UC San Diego Library Digital Collections. Dataset. https://doi.org/10.6075/J0S75FMB

Thin section electron microscopy of diaphragm (skeletal) muscle from a wild type mouse.

Sample was viewed with a Hitachi 7600 electron microscope (accelerating voltage 80 KV) and imaged with an AMT digital camera. Image taken at 30,000X magnification.

This image is part of a set of wild type diaphragm muscle images that served as controls for the study of the delta-sarcoglycan knockout mouse. Both the set of wild-type and delta-sarcoglycan knockout mouse images are part of The CELL: an image library.

Reference: Nat Med. 2008 Apr;14(4):442-7.
Genetic and pharmacologic inhibition of mitochondrial-dependent necrosis attenuates muscular dystrophy.
Millay DP, Sargent MA, Osinska H, Baines CP, Barton ER, Vuagniaux G, Sweeney HL, Robbins J, Molkentin JD (tissue preparation described in Fewell JG, et al. A treadmill exercise regimen for identifying cardiovascular phenotypes in transgenic mice. Am J Physiol. 1997;273:H1595–H1605)

• 2021

• Osinska, Hanna

Preparation: glutaraldehyde fixed tissue; osmium tetroxide fixed tissue
Relation to intact cell: microtome-sectioned tissue
Item type: recorded image
Imaging mode: transmission electron microscopy (TEM)
Parameter imaged: electron density
Source of contrast: uranyl salt; lead salt
Visualization methods: detection of electrons
Processing history: unprocessed raw data

• Cell Image Library Group ID: 7750

• Mus musculus

• Dystroglycan complex
• Skeletal muscle cell

• Plasma membrane organization
• Structural molecule activity

• data
• image

• No linguistic content; Not applicable

Samplenumber: 252

Doi: https://doi.org/10.6075/J0S75FMB

Source data

• Source Record in the Cell Image Library: https://doi.org/10.7295/W9CIL252

Reference

• PubMed article: https://www.ncbi.nlm.nih.gov/pubmed/?term=18345011

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2022-08-12