Shelton, Emma; Orenstein, Jan (2021). CIL:13091, Mus musculus, macrophage, lymphocyte. In Cell Image Library. UC San Diego Library Digital Collections. Dataset. https://doi.org/10.6075/J0NZ86FB

This image shows two different types of white blood cells from a mouse which are essential for mammalian immune response to protect from infection. The larger cell is a macrophage and the smaller two are leukocytes such as t-cells. Here, the cell types differ in surface texture (or morphology); the macrophage has surface folds and dense microvilli, whereas the surface of the lymphocytes is comparatively smooth with sparse microvilli. Both cell types respond to neighboring cells by extending longer microvilli (arrows). The folds and microvilli protrude due to f-actin networks under the cell membrane. Image courtesy of Emma Shelton and Jan Orenstein appears as Figure 34 from Chapter 2 (Specializations Of The Free Surface) of 'The Cell, 2nd Ed.' by Don W. Fawcett M.D. A PDF copy of the accompanying chapter is available on the ASCB's BioEDUCATE website.

• 2021

• Orenstein, Jan
• Shelton, Emma

Scanning electron micrograph.

Preparation: critical_point dried specimen
Relation to intact cell: dispersed cells in vitro
Item type: scanning electron microscopy (SEM)
Imaging mode: illumination by electrons; secondary_electron imaging
Parameter imaged: secondary electron generation
Processing history: chemically fixed tissue
Data qualification: Processed

• Cell Image Library Group ID: 11228

• Mus musculus

• Lymphocyte
• Macrophage
• Microvillus
• Plasma membrane

• Cell projection organization
• Immune system process

• data
• image

• No linguistic content; Not applicable

Samplenumber: 13091

Doi: https://doi.org/10.6075/J0NZ86FB

Source data

• Source Record in the Cell Image Library: https://doi.org/10.7295/W9CIL13091

Other resource

• Fawcett, Don W. "The Cell." 2nd ed., W.B. Saunders, 1981, ISBN 0721635849. https://www.ascb.org/career-development/teaching/don-fawcetts-the-cell/

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2022-08-12