Microscopy product ID: 3948
Reconstruction
Description | Virological synapse formed between HTLV-1 infected CD4+ T-cell (PBMC) and an autologous uninfected CD4+ T-cell as a target cell. These cells were stained against HTLV-1 Gag p19 matrix protein with a specific monoclonal antibody (GIN7). A large immunolabeled HTLV-1 particle is visible between the two cell membranes. See Figure 4D of Majorovits et al., 2008. |
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Description | Tomographic reconstruction in MRC format. Filename = map_3948.ccp4 |
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Description | Animation through computed slices of tomographic reconstruction of a virilogical synapse formed between HTLV-1 infected CD4+ T-cell (PBMC) and an autologous uninfected CD4+ T-cell as a target cell. These cells were stained against HTLV-1 Gag p19 matrix protein with a specific monoclonal antibody (GIN7). A large immunolabeled HTLV-1 particle is visible between the two cell membranes. |
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- Cite This Work
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Majorovits, Endre; Bangham, Charles; Fuller, Stephen; Nejmeddine, Mohamed (2017). Microscopy product ID: 3948. In Cell Centered Database. UC San Diego Library Digital Collections. https://doi.org/10.6075/J0QJ7H3P
- Creation Date
- Microscopy product: 2007-02-27. Project: 2004-02-02 to 2007-06-30.
- Date Issued
- 2017
- Research Team Head
- Researchers
- Technical Details
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Product type: SINGLE TILT. Microscopy type: TEM. Instrument: FEI Tecnai F30 FEG
- Funding
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Wellcome Trust
- Series
- Scientific Name
- Anatomy
- Topic
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- Language
- No linguistic content; Not applicable
- Related Resources
- Majorovits E, Nejmeddine M, Tanaka Y, Taylor GP, Fuller SD, Bangham CRM (2008). Human T-lymphotropic virus-1 visualized at the virological synapse by electron tomography. PLoS ONE 3(5):e2251. PubMed: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2386264/; PLoS ONE. https://doi.org/10.1371/journal.pone.0002251
- Microscopy product 3948 at the Cell Centered Database: https://doi.org/10.7295/W9CCDB3948
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- License
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Creative Commons Attribution 4.0 International Public License
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- UC Regents
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Under copyright (US)
Use: This work is available from the UC San Diego Library. This digital copy of the work is intended to support research, teaching, and private study.
Constraint(s) on Use: This work is protected by the U.S. Copyright Law (Title 17, U.S.C.). Use of this work beyond that allowed by "fair use" or any license applied to this work requires written permission of the copyright holder(s). Responsibility for obtaining permissions and any use and distribution of this work rests exclusively with the user and not the UC San Diego Library. Inquiries can be made to the UC San Diego Library program having custody of the work.
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Research Data Curation Program, UC San Diego, La Jolla, 92093-0175 (https://lib.ucsd.edu/rdcp)
- Last Modified
2023-05-22