Microscopy product ID: 971268
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Description | Surface rendering of a manual segmentation of contiguous intracellular membrane segments from a tomographic reconstruction of a hippocampal area CA1 stratum radiatum from an adult transgenic mouse over-expressing human wild-type alpha-synuclein. |
Reconstruction
Description | Tomographic reconstruction from hippocampus CA1 of AS-Tg mice revealed large presynaptic nerve terminals filled with tubulovesicular structures. |
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Boassa, Daniela; Berlanga, Monica L.; Yang, Mary Ann; Terada, Masako; Hu, Junru; Bushong, Eric A.; Hwang, Minju; Masliah, Eliezer; George, Julia M.; Ellisman, Mark H. (2017). Microscopy product ID: 971268. In Cell Centered Database. UC San Diego Library Digital Collections. https://doi.org/10.6075/J0W66KKH
- Date Issued
- 2017
- Research Team Head
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- Technical Details
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Male. Strain: Line D, PDGF-human alpha-synuclein
Product type: SERIAL SECTION. Microscopy type: Serial Block Face SEM. Instrument: JEOL JEM4000EX-1
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- Anatomy
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- Related Resources
- Boassa D, Berlanga ML, Yang MA, Terada M, Hu J, Bushong EA, Hwang M, Masliah E, George JM, Ellisman MH (2013). Mapping the subcellular distribution of alpha-synuclein in neurons using genetically encoded probes for correlated light and electron microscopy: Implications for Parkinson's disease pathogenesis. J Neurosci, 33(6):2605-2615. PubMed: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3711410/; Journal of Neuroscience. https://doi.org/10.1523/JNEUROSCI.2898-12.2013
- Microscopy product 971268 at the Cell Centered Database: https://doi.org/10.7295/W9CCDB971268
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Creative Commons Attribution 4.0 International Public License
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Under copyright (US)
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Research Data Curation Program, UC San Diego, La Jolla, 92093-0175 (https://lib.ucsd.edu/rdcp)
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2023-05-22