BindingDB: Measured Binding Data for Protein-Ligand and Other Molecular Systems
BindingDB: Measured Binding Data for Protein-Ligand and Other Molecular Systems
About this collection
- Extent
-
5 digital objects.
- Cite This Work
-
Gilson, Michael K.; Liu, Tiqing (2023). BindingDB: Measured Binding Data for Protein-Ligand and Other Molecular Systems. UC San Diego Library Digital Collections. https://doi.org/10.6075/J0HD7VVF
- Description
-
This collection contains the data in BindingDB, a large database launched in 2000 that supports research, education and practice in drug discovery, pharmacology, computer-aided drug design, machine-learning and artificial intelligence, and related fields by collecting experimentally measured protein-small molecule binding data, as well as selected collections of other types of binding data, such as host-guest and protein-protein, chiefly from scientific articles and patents.
- Date Collected
- 2000 to present
- Date Issued
- 2023
- Principal Investigator
- Research Team Member
- Topics
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- Affinity
- Antibody
- Artificial intelligence
- Binding
- Computational chemistry
- Database
- Dissociation constant (Kd)
- Drug
- Drug discovery
- Free energy
- Half maximal inhibitory concentration (IC50)
- Host-guest
- Ligand
- Machine learning
- Medicinal chemistry
- Medicine
- Protein
- Protein-protein
- Simplified Molecular Input Line Entry System (SMILES)
- Small molecule
- UniProt
Formats
View formats within this collection
- Language
- English
- Identifier
-
Identifier: Michael K. Gilson: https://orcid.org/0000-0002-3375-1738
Identifier: Tiqing Liu: https://orcid.org/0000-0002-3429-9333
- Related Resources
- 2001: Chen, X., Liu, M., and Gilson, M.K. Binding DB: A web-accessible molecular recognition database J. Combi. Chem. High-Throughput Screen 4:719-725(2001). https://doi.org/10.2174/1386207013330670
- 2007: Liu, T., Lin, Y., Wen, X., Jorrisen, R.N. and Gilson, M.K. BindingDB: a web-accessible database of experimentally determined protein-ligand binding affinities Nucleic Acids Research 35:D198-D201 (2007). https://doi.org/10.1093/nar/gkl999
- 2016: Gilson, M.K., Liu, T., Baitaluk, M., Nicola, G., Hwang, L. and Chong, J. BindingDB in 2015: A public database for medicinal chemistry, computational chemistry and systems pharmacology. Nucleic Acids Research 44:D1045-D1053 (2016). https://doi.org/10.1093/nar/gkv1072
- ChEMBL: https://www.ebi.ac.uk/chembl/
- Chemical Entities of Biological Interest (ChEBI): https://www.ebi.ac.uk/chebi/
- Community Structure-Activity Resource (CSAR): http://www.csardock.org/
- Drug Design Data Resource (D3R): https://drugdesigndata.org/
- DrugBank: https://go.drugbank.com/
- International Union of Basic and Clinical Pharmacology / British Pharmacological Society Guide to Pharmacology: https://www.guidetopharmacology.org/
- KEGG: Kyoto Encyclopedia of Genes and Genomes: https://www.genome.jp/kegg/
- PDSP Ki: https://pdsp.unc.edu/databases/kidb.php
- Protein Data Bank archive (PDB): https://www.wwpdb.org/
- PubChem: https://pubchem.ncbi.nlm.nih.gov/
- PubMed: https://pubmed.ncbi.nlm.nih.gov/
- UniProt Knowledgebase (UniProtKB): https://www.uniprot.org/
- ZINC: https://zinc.docking.org/
Primary associated publication
Interactive viewer
Reference