Autopsy Review of HSCT recipients, UCSD, 2001-2010

• Restricted to UC San Diego use only

• 2011

• Thirakul, Phoutthasone

Patients undergoing hematopoietic stem cell transplant (HSCT) face potentially life-threatening complications related to chemotherapy cytotoxicity, graft versus host disease (GVHD), and bacterial, viral, and fungal infections. Autopsy studies on post-HSCT patients are limited, and when available, serve to confirm ante-mortem diagnoses, as well as to reveal occult processes that were clinically unsuspected. We undertook a 10-year (2001-2010) retrospective review of autopsy reports of HSCT recipients within the University of California, San Diego Department of Medicine/Bone Marrow Transplant division to relate ante -mortem to post-mortem cause of mortality. The most common cause of death in the allogeneic group was fungal infections (8/30, 26.7%) followed by sepsis (7/30, 23%), disease progression (4/30, 13%), GVHD (4/10, 10%), CMV (3/ 10, 10%), VOD (2/30, 6.7%), septic emboli (1/30, 3.3%), pneumonia of unknown organism (1/30, 3.3%), and DAD (1/30, 3.3%). The most common cause of death in the auto- transplant group was CMV infection (2/4, 50%), followed by disease progression (1/4, 25%) and subarachnoid hemorrhage (1/2, 25%)

1 online resource ([10] p.)

• Academic Dissertations

• Dissertations, Academic--School of Medicine. (Discipline)--UCSD

• text

Thesis (M.D.)--University of California, San Diego, 2011

Forms part of the UCSD School of Medicine independent study projects, Class of 2011

Includes bibliographical references (p. [9]-[10])

• Phoutthasone Thirakul

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2020-10-22