Autopsy Review of HSCT recipients, UCSD, 2001-2010
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- Restricted to UC San Diego use only
- Collection
- Creation Date
- 2011
- Creator
- Abstract
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Patients undergoing hematopoietic stem cell transplant (HSCT) face potentially life-threatening complications related to chemotherapy cytotoxicity, graft versus host disease (GVHD), and bacterial, viral, and fungal infections. Autopsy studies on post-HSCT patients are limited, and when available, serve to confirm ante-mortem diagnoses, as well as to reveal occult processes that were clinically unsuspected. We undertook a 10-year (2001-2010) retrospective review of autopsy reports of HSCT recipients within the University of California, San Diego Department of Medicine/Bone Marrow Transplant division to relate ante -mortem to post-mortem cause of mortality. The most common cause of death in the allogeneic group was fungal infections (8/30, 26.7%) followed by sepsis (7/30, 23%), disease progression (4/30, 13%), GVHD (4/10, 10%), CMV (3/ 10, 10%), VOD (2/30, 6.7%), septic emboli (1/30, 3.3%), pneumonia of unknown organism (1/30, 3.3%), and DAD (1/30, 3.3%). The most common cause of death in the auto- transplant group was CMV infection (2/4, 50%), followed by disease progression (1/4, 25%) and subarachnoid hemorrhage (1/2, 25%)
- Physical Description
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1 online resource ([10] p.)
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- Thesis
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Thesis (M.D.)--University of California, San Diego, 2011
- General Note
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Forms part of the UCSD School of Medicine independent study projects, Class of 2011
Includes bibliographical references (p. [9]-[10])
- Rights Holder
- Phoutthasone Thirakul
- Copyright
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Under copyright (US)
Use: This work is available from the UC San Diego Libraries. This digital copy of the work is intended to support research, teaching, and private study.
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Academic Liaison Program, University of California, San Diego, La Jolla, 92093-0175 (http://ucsd.libguides.com/c.php?g=91092&p=584168)
- Last Modified
2020-10-22