{"CIL_CCDB":{"Status":{"Is_public":true,"Deleted":false,"Publish_time":1294203600},"Data_type":{"Still_image":true,"Z_stack":false,"Video":false,"Time_series":false},"CIL":{"Image_files":[{"File_type":"Jpeg","File_path":"10976.jpg","Size":473025,"Mime_type":"image\/jpeg; charset=utf-8"},{"File_type":"OME_tif","File_path":"10976.tif","Size":1200000,"Mime_type":"image\/tif"},{"File_type":"Zip","File_path":"10976.zip","Size":1407260,"Mime_type":"application\/zip"}],"CORE":{"ATTRIBUTION":{"URLs":[{"Label":"ASCB BioEDUCATE Program","Href":"http:\/\/www.ascb.org\/bioeducate\/FawcettTheCell.htm"}],"PUBLISHED":["ISBN 0721635849","from: Don W. Fawcett M.D  \u2018The Cell\u2019 2nd edition, W.B. Saunders  Chapter 4 (Nucleus)"],"Contributors":["Don W. Fawcett"]},"BIOLOGICALPROCESS":[{"onto_name":"nucleus organization","onto_id":"GO:0006997"},{"onto_name":"nucleolus organization","onto_id":"GO:0007000"},{"onto_name":"chromatin organization","onto_id":"GO:0006325"}],"PROCESSINGHISTORY":{"free_text":"Image extracted from .pdf file of 'The Cell'"},"PARAMETERIMAGED":{"onto_name":"electron density","onto_id":"FBbi:00000315"},"IMAGEDESCRIPTION":{"free_text":"Transmission electron micrograph of nucleus showing the characteristic features of glutaraldehyde fixation introduced as a primary fixative in 1962 and since used routinely. Chromatin appears differentiated into coarse, darkly stained heterochromatin that accumulates near the nuclear periphery and the nucleolus and less darkly staining euchromatin. In contrast, chromatin appears uniformly stained with osmium tetroxide as primary fixative (for example, see CIL image 10974, in this image group).  Figure 113 from Chapter 4 (Nucleus) of 'The Cell, 2nd Ed.' by Don W. Fawcett M.D.  A PDF copy of the corresponding chapter is available on the ASCB's BioEDUCATE website."},"ITEMTYPE":{"onto_name":"film","onto_id":"FBbi:00000303"},"CELLULARCOMPONENT":[{"onto_name":"nucleus","onto_id":"GO:0005634"},{"onto_name":"nucleolus","onto_id":"GO:0005730"},{"onto_name":"chromatin","onto_id":"GO:0000785"},{"onto_name":"rough endoplasmic reticulum","onto_id":"GO:0005791"},{"onto_name":"ribosome","onto_id":"GO:0005840"},{"onto_name":"nuclear heterochromatin","onto_id":"GO:0005720"},{"onto_name":"nuclear envelope","onto_id":"GO:0005635"}],"RELATIONTOINTACTCELL":{"onto_name":"microtome-sectioned tissue","onto_id":"FBbi:00000029"},"SOURCEOFCONTRAST":{"onto_name":"differences in adsorption or binding of stain","onto_id":"FBbi:00000598"},"GROUP_ID":"11224","DATAQUALIFICATION":{"free_text":"PROCESSED"},"TERMSANDCONDITIONS":{"free_text":"attribution_nc_nd"},"IMAGINGMODE":[{"onto_name":"transmission electron microscopy (TEM)","onto_id":"FBbi:00000258"},{"onto_name":"detection of electrons","onto_id":"FBbi:00000375"}],"DIMENSION":[{"Space":{"Image_size":883,"axis":"X"}},{"Space":{"Image_size":1272,"axis":"Y"}}],"NCBIORGANISMALCLASSIFICATION":{"onto_name":"Myotis lucifugus","onto_id":"NCBITaxon:59463"},"PREPARATION":[{"onto_name":"tissue in plastic embedment","onto_id":"FBbi:00000016"},{"onto_name":"osmium tetroxide fixed tissue","onto_id":"FBbi:00000012"},{"onto_name":"glutaraldehyde fixed tissue","onto_id":"FBbi:00000011"}],"VISUALIZATIONMETHODS":[{"onto_name":"uranyl salt","onto_id":"FBbi:00000569"},{"onto_name":"osmium tetroxide","onto_id":"FBbi:00000571"},{"onto_name":"lead salt","onto_id":"FBbi:00000570"}],"CELLTYPE":{"onto_name":"pancreatic acinar cell","onto_id":"CL:0002064"}}},"Citation":{"Title":"Don W. Fawcett (2011) CIL:10976, Myotis lucifugus, pancreatic acinar cell. CIL. Dataset","ARK":"ark:\/b7295\/w9cil10976","DOI":"doi:10.7295\/W9CIL10976"}}}