Palay, Sanford (2021). CIL:37228, neuron. In Cell Image Library. UC San Diego Library Digital Collections. Dataset. https://doi.org/10.6075/J0C24V29

Transmission electron micrograph of a nerve cell synapsing on a dendrite. The synapse contains many synaptic vesicles and a cluster of mitochondria.
Note that this very early (1953) micrograph is primarily of historical interest since it pre-dates glutaraldehye fixation which was introduced in the early 60's and is considered essential for adequate nerve tissue preservation. Examples of nerve tissue micrographs prepared in 1965 are CIL:37218, CIL:37219 and CIL:37220.
Image made available by James D. Jamieson and the Department of Cell Biology, Yale University School of Medicine.

• 1953-10-27

• 2021

• Palay, Sanford

Original 3.25 in. x 4 in. lantern slides were scanned at 600dpi. Original magnification x35,000.

Preparation: chemically fixed tissue
Relation to intact cell: sectioned tissue
Item type: recorded image
Imaging mode: transmission electron microscopy (TEM)
Parameter imaged: electron density
Source of contrast: differences in adsorption or binding of stain
Visualization methods: osmium tetroxide
Processing history: unprocessed raw data

• Cell Image Library Group ID: 11327

• Dendrite
• Neuron
• Synapse
• Synaptic vesicle

• Transmission of nerve impulse

• data
• image

• No linguistic content; Not applicable

Samplenumber: 37228

Doi: https://doi.org/10.6075/J0C24V29

Source data

• Source Record in the Cell Image Library: https://doi.org/10.7295/W9CIL37228

Other resource

• George E. Palade EM Slide Collection: http://cushing.med.yale.edu/gsdl/cgi-bin/library?c=palade&a=d&d=DpaladeNerI

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2023-08-17