Young, Rob (2021). CIL:38996, Homo sapiens. In Cell Image Library. UC San Diego Library Digital Collections. Dataset. https://doi.org/10.6075/J0Z89B7K

Transmission electron micrograph showing collagen fibrils exhibiting focal swelling and loss of periodic cross banding in the trabecular meshwork of a person with glaucoma. The trabecular meshwork is the structure through which the aqueous humor in the anterior chamber drains into Schlemm's canal. The obstruction of this process may represent a mechanism by which the intraocullar pressure is raised in glaucoma. The proteoglycans that are normally attached to the collagen fibrils have become detached and are seen as small short filaments. The intact fibrils are approximately 120 nm in diameter.

• 2021

• Young, Rob

B0001823 Degenerating collagen fibrils in glaucoma. Wellcome Images available under the following creative commons usage http://creativecommons.org/licenses/by-nc-nd/2.0/uk/

Preparation: chemically fixed tissue
Relation to intact cell: sectioned tissue
Item type: recorded image
Imaging mode: transmission electron microscopy (TEM)
Parameter imaged: electron density
Source of contrast: differences in adsorption or binding of stain
Visualization methods: uranyl salt; cationic dye
Processing history: unprocessed raw data

• Cell Image Library Group ID: 11757

• Homo sapiens

• Collagen
• Extracellular matrix
• Trabecular meshwork

• Collagen fibril organization
• Glaucoma

• data
• image

• No linguistic content; Not applicable

Samplenumber: 38996

Doi: https://doi.org/10.6075/J0Z89B7K

Source data

• Source Record in the Cell Image Library: https://doi.org/10.7295/W9CIL38996

Other resource

• Wellcome Images: http://images.wellcome.ac.uk/

Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International Public License

• UC Regents

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2022-08-12